Results 31 to 40 of about 60,239 (217)

Sex-Related Differences in the Pharmacological Response in SARS-CoV-2 Infection, Dyslipidemia, and Diabetes Mellitus: A Narrative Review

Pharmaceuticals, 2023
Pharmacological responses vary by sex in several illnesses. This narrative review summarizes sex variations in pharmaceutical response in SARS-CoV-2 infection, dyslipidemia, and diabetes mellitus.
Adelina Lombrea, Mirabela Romanescu, Narcisa Jianu, Minodora Andor, Maria Suciu, Dana Emilia Man, Corina Danciu, Cristina Adriana Dehelean, Valentina Buda   +8 more
doaj   +1 more source

Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions

Particle and Fibre Toxicology, 2017
Background As nanoparticles (NPs) become more prevalent in the pharmaceutical industry, questions have arisen from both industry and regulatory stakeholders about the long term effects of these materials. This study was designed to evaluate whether gold (
James L. Weaver, Grainne A. Tobin, Taylor Ingle, Simona Bancos, David Stevens, Rodney Rouse, Kristina E. Howard, David Goodwin, Alan Knapton, Xiaohong Li, Katherine Shea, Sharron Stewart, Lin Xu, Peter L. Goering, Qin Zhang, Paul C. Howard, Jessie Collins, Saeed Khan, Kidon Sung, Katherine M. Tyner   +19 more
doaj   +1 more source

Use of two functional monomers for a new approach to the synthesis of a magnetic molecularly imprinted polymer for ciprofloxacin

Journal of Materials Research and Technology, 2021
Ciprofloxacin is an antibiotic widely used in the treatment of human and animal diseases and can be found as a contaminant in some foods of animal origin, such as milk.
Lucas M. Silva, Marcos V. Foguel, Maria del Pilar T. Sotomayor   +2 more
doaj   +1 more source

Targeted review of maximum residue levels (MRLs) for fenpropathrin

EFSA Journal, 2023
In accordance with Article 43 of Regulation (EC) 396/2005, EFSA received a request from the European Commission to review the existing maximum residue levels (MRLs) for the non‐approved active substance fenpropathrin in view of the possible lowering of ...
European Food Safety Authority (EFSA), Giulia Bellisai, Giovanni Bernasconi, Marco Binaglia, Alba Brancato, Luis Carrasco Cabrera, Irene Castellan, Anna Federica Castoldi, Arianna Chiusolo, Federica Crivellente, Monica Del Aguila, Lucien Ferreira, German Giner Santonja, Luna Greco, Frederique Istace, Samira Jarrah, Anna Lanzoni, Renata Leuschner, Iris Mangas, Ileana Miron, Stefanie Nave, Martina Panzarea, Juan Manuel Parra Morte, Ragnor Pedersen, Hermine Reich, Silvia Ruocco, Miguel Santos, Alessia Pia Scarlato, Andrea Terron, Anne Theobald, Manuela Tiramani, Alessia Verani   +31 more
doaj   +1 more source

Targeted review of maximum residue levels (MRLs) for endosulfan

EFSA Journal, 2023
In accordance with Article 43 of Regulation (EC) 396/2005, EFSA received a request from the European Commission to review the existing maximum residue levels (MRLs) for the non‐approved active substance endosulfan in view of the possible lowering of the ...
European Food Safety Authority (EFSA), Giulia Bellisai, Giovanni Bernasconi, Marco Binaglia, Luis Carrasco Cabrera, Irene Castellan, Anna Federica Castoldi, Arianna Chiusolo, Federica Crivellente, Monica Del Aguila, Lucien Ferreira, German Giner Santonja, Luna Greco, Frederique Istace, Samira Jarrah, Anna Lanzoni, Renata Leuschner, Iris Mangas, Ileana Miron, Stefanie Nave, Martina Panzarea, Juan Manuel Parra Morte, Ragnor Pedersen, Hermine Reich, Silvia Ruocco, Miguel Santos, Alessia Pia Scarlato, Andrea Terron, Anne Theobald, Manuela Tiramani, Alessia Verani   +30 more
doaj   +1 more source

A Propidium Monoazide (PMAxx)-Droplet Digital PCR (ddPCR) for the Detection of Viable Burkholderia cepacia Complex in Nuclease-Free Water and Antiseptics

Microorganisms, 2022
Pharmaceutical products contaminated with Burkholderia cepacia complex (BCC) strains constitute a serious health issue for susceptible individuals. New detection methods to distinguish DNA from viable cells are required to ensure pharmaceutical product ...
Soumana Daddy Gaoh, Ohgew Kweon, Yong-Jin Lee, David Hussong, Bernard Marasa, Youngbeom Ahn   +5 more
doaj   +1 more source

Investigation of microorganisms in cannabis after heating in a commercial vaporizer

Frontiers in Cellular and Infection Microbiology, 2023
IntroductionThere are concerns about microorganisms present on cannabis materials used in clinical settings by individuals whose health status is already compromised and are likely more susceptible to opportunistic infections from microbial populations ...
Danielle S. Sopovski, Jing Han, Marla Stevens-Riley, Qiang Wang, Bruce D. Erickson, Berk Oktem, Michelle Vanlandingham, Cassandra L. Taylor, Steven L. Foley   +8 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The C30-Modulation of Betulinic Acid Using 1,2,4-Triazole: A Promising Strategy for Increasing Its Antimelanoma Cytotoxic Potential

Molecules, 2022
Cancer, in all its types and manifestations, remains one of the most frequent causes of death worldwide; an important number of anticancer drugs have been developed from plants, fungi and animals, starting with natural compounds that were later ...
Gabriela Nistor, Marius Mioc, Alexandra Mioc, Mihaela Balan-Porcarasu, Roxana Racoviceanu, Alexandra Prodea, Andreea Milan, Roxana Ghiulai, Alexandra Semenescu, Cristina Dehelean, Codruța Șoica   +10 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source