Results 11 to 20 of about 53,939 (264)

Skin Sensitization Potential and Cellular ROS-Induced Cytotoxicity of Silica Nanoparticles

open access: yesNanomaterials, 2021
Nowadays, various industries using nanomaterials are growing rapidly, and in particular, as the commercialization and use of nanomaterials increase in the cosmetic field, the possibility of exposure of nanomaterials to the skin of product producers and ...
Sung-Hyun Kim   +7 more
doaj   +1 more source

Effect of Pulmonary Inflammation by Surface Functionalization of Zinc Oxide Nanoparticles

open access: yesToxics, 2021
Zinc oxide nanoparticles (ZnO NPs) are used in various industries such as food additives, cosmetics, and biomedical applications. In this study, we evaluated lung damage over time by three types of ZnO NPs (L-serine, citrate, and pristine) following the ...
Ayoung Jung   +6 more
doaj   +1 more source

Colony-Forming Efficiency Assay to Assess Nanotoxicity of Graphene Nanomaterials

open access: yesToxics, 2022
The nano-market has grown rapidly over the past decades and a wide variety of products are now being manufactured, including those for biomedical applications.
Hansol Won   +6 more
doaj   +1 more source

Evaluation of skin phototoxicity of transdermally administered pharmaceuticals in Sprague-Dawley rats

open access: yesLaboratory Animal Research, 2020
Some drugs cause phototoxicity in humans when exposed to light, thus there is a need for an in vivo phototoxicity test to evaluate them. However, an in vivo phototoxicity test method to evaluate this has not been established.
Nam Hee Youn   +7 more
doaj   +1 more source

In Vivo Evaluation of the Oral Toxicity of the Chlorobutanol

open access: yesToxics, 2022
Chlorobutanol (CB) is used as a preservative in cosmetics and has antibacterial activity. This study investigated the single- and repeated-dose 28-day oral toxicity of a CB solvent in Sprague Dawley (SD) rats.
Dahye Jeong   +7 more
doaj   +1 more source

Informing selection of drugs for COVID-19 treatment through adverse events analysis

open access: yesScientific Reports, 2021
Coronavirus disease 2019 (COVID-19) is an ongoing pandemic and there is an urgent need for safe and effective drugs for COVID-19 treatment. Since developing a new drug is time consuming, many approved or investigational drugs have been repurposed for ...
Wenjing Guo   +10 more
doaj   +1 more source

Effects of Oviductus Ranae on Follicular Developmental Dysfunction by Tripterygium in Rats

open access: yesShipin gongye ke-ji, 2023
Objective: To study the effect of oviductus ranae (OR) on follicle development and phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt) signaling pathway in the ovaries of follicular developmental dysfunction rats.
Xueyuan SUN   +6 more
doaj   +1 more source

Evaluation of the Skin Sensitization Potential of Carbon Nanotubes Using Alternative In Vitro and In Vivo Assays

open access: yesToxics, 2020
Carbon nanotubes (CNTs) are one of the major types of nanomaterials that have various industrial and biomedical applications. However, there is a risk of accidental exposure to CNTs in individuals involved in their large-scale production and in ...
Sung-Hyun Kim   +9 more
doaj   +1 more source

The Anti-Melanoma Effect of Betulinic Acid Functionalized Gold Nanoparticles: A Mechanistic In Vitro Approach

open access: yesPharmaceuticals, 2022
Implementing metallic nanoparticles as research instruments for the transport of therapeutically active compounds remains a fundamentally vital work direction that can still potentially generate novelties in the field of drug formulation development ...
Roxana Ghiulai   +11 more
doaj   +1 more source

Orally Administered 6:2 Chlorinated Polyfluorinated Ether Sulfonate (F-53B) Causes Thyroid Dysfunction in Rats

open access: yesToxics, 2020
The compound 6:2 chlorinated polyfluorinated ether sulfonate (F-53B), a replacement for perfluorooctanesulfonate (PFOS) in the electroplating industry, has been widely detected in numerous environmental matrices, human sera, and organisms.
So-Hye Hong   +10 more
doaj   +1 more source

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