Results 11 to 20 of about 160,346 (305)

The Anti-Melanoma Effect of Betulinic Acid Functionalized Gold Nanoparticles: A Mechanistic In Vitro Approach

open access: yesPharmaceuticals, 2022
Implementing metallic nanoparticles as research instruments for the transport of therapeutically active compounds remains a fundamentally vital work direction that can still potentially generate novelties in the field of drug formulation development ...
Roxana Ghiulai   +11 more
doaj   +1 more source

Evaluation of the Skin Sensitization Potential of Carbon Nanotubes Using Alternative In Vitro and In Vivo Assays

open access: yesToxics, 2020
Carbon nanotubes (CNTs) are one of the major types of nanomaterials that have various industrial and biomedical applications. However, there is a risk of accidental exposure to CNTs in individuals involved in their large-scale production and in ...
Sung-Hyun Kim   +9 more
doaj   +1 more source

Sugarcane bagasse biochar pellets for removal of caffeine, norfloxacin, and ciprofloxacin in aqueous samples

open access: yesEclética Química, 2022
This work investigates the physicochemical properties of a biochar obtained from sugarcane bagasse by torrefaction at four different temperatures (260, 270, 280, and 290 °C), without chemical or physical activation.
Mateus Cottorello Fonsêca   +7 more
doaj   +1 more source

Orally Administered 6:2 Chlorinated Polyfluorinated Ether Sulfonate (F-53B) Causes Thyroid Dysfunction in Rats

open access: yesToxics, 2020
The compound 6:2 chlorinated polyfluorinated ether sulfonate (F-53B), a replacement for perfluorooctanesulfonate (PFOS) in the electroplating industry, has been widely detected in numerous environmental matrices, human sera, and organisms.
So-Hye Hong   +10 more
doaj   +1 more source

Deep Learning Models for Predicting Gas Adsorption Capacity of Nanomaterials

open access: yesNanomaterials, 2022
Metal–organic frameworks (MOFs), a class of porous nanomaterials, have been widely used in gas adsorption-based applications due to their high porosities and chemical tunability.
Wenjing Guo   +7 more
doaj   +1 more source

Comparison of commonly used ICR stocks and the characterization of Korl:ICR

open access: yesLaboratory Animal Research, 2017
Mouse is a commonly used animal in life science studies and is classified as outbred if genetically diverse and inbred if genetically homogeneous. Outbred mouse stocks, are used in toxicology, oncology, infection and pharmacology research.
Hye-Jun Shin   +7 more
doaj   +1 more source

Non-alcoholic fatty liver disease-associated DNA methylation and gene expression alterations in the livers of Collaborative Cross mice fed an obesogenic high-fat and high-sucrose diet

open access: yesEpigenetics, 2022
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent chronic liver disease, and patient susceptibility to its onset and progression is influenced by several factors.
Volodymyr P. Tryndyak   +6 more
doaj   +1 more source

Genotoxicity assessment of piperitenone oxide: an in vitro and in silico evaluation [PDF]

open access: yes, 2017
Piperitenone oxide, a natural flavouring agent also known as rotundifolone, has been studied for the genotoxicity assessment by an integrated in vitro and in silico experimental approach, including the bacterial reverse mutation assay, the micronucleus ...
Abete, Lorena   +9 more
core   +1 more source

Post-mortem toxicology: A pilot study to evaluate the use of a Bayesian network to assess the likelihood of fatality [PDF]

open access: yes, 2015
The challenge of interpreting post-mortem drug concentrations is well documented and relies on appropriate sample collection, knowledge of case circumstances as well as reference to published tables of data, whilst taking into account the known issues of
Bolton, Jennifer   +3 more
core   +1 more source

A Systematic Review on the Role of SIRT1 in Duchenne Muscular Dystrophy

open access: yesCells, 2021
Duchenne muscular dystrophy (DMD) is a muscular disease characterized by progressive muscle degeneration. Life expectancy is between 30 and 50 years, and death is correlated with cardiac or respiratory complications. Currently, there is no cure, so there
Elisa Domi   +3 more
doaj   +1 more source

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