Results 1 to 10 of about 14,204,415 (185)

Intermediate-dose cytarabine is an effective therapy for adults with non-Langerhans cell histiocytosis [PDF]

Orphanet Journal of Rare Diseases, 2022
Background Non-Langerhans cell histiocytosis, including Erdheim–Chester disease (ECD), Rosai–Dorfman disease (RDD), indeterminate cell histiocytosis (ICH), and unclassified histiocytosis, is a rare disorder lacking a standard treatment strategy.
Ting Liu, Hua-cong Cai, Hao Cai, Miao Chen, Wei Zhang, Jian Li, Dao-bin Zhou, Xin-xin Cao   +7 more
doaj   +2 more sources

Case of Non-Langerhans Cell Histiocytosis in a Person Living with HIV - Clinical and Therapeutic Challenge [PDF]

Journal of the International Association of Providers of AIDS Care, 2022
Non-Langerhans cell histiocytosis is a rare disease which seldom affects adults. We report a case of a 32-year-old Bulgarian woman living with HIV. She developed severe anemia, extreme splenomegaly, requiring splenectomy and vertebral tumor formations ...
Nina Yancheva, Dimitar Strashimirov, Dragomir Dardanov, Bojidar Kamenov, Atanas Radinoff   +4 more
doaj   +2 more sources

Successful Treatment of Non-Langerhans Cell Histiocytosis With Topical Rapamycin in Two Pediatric Cases [PDF]

Clinical, Cosmetic and Investigational Dermatology, 2022
Raden Mohamad Rendy Ariezal Effendi, Trustia Rizqandaru, Renata Yuliasari, Srie Prihianti Gondokaryono, Inne Arline Diana, Reiva Farah Dwiyana Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr.
Effendi RMRA, Rizqandaru T, Yuliasari R, Gondokaryono SP, Diana IA, Dwiyana RF   +5 more
doaj   +2 more sources

Targeted proteomics reveal histiocytosis-associated neurodegeneration signatures. [PDF]

Hemasphere
Abstract Neurodegeneration (ND) is a severe complication of Langerhans cell histiocytosis (LCH), yet its underlying biology and reliable biomarkers remain poorly defined. The aim of this study was to (1) gain insight into neuroimmunological mechanisms governing ND and (2) assess the clinical value of established and novel biomarkers for ND‐LCH.
Kvedaraite E, Lourda M, Munting JB, Papo M, Jädersten M, Shioda Y, Sakamoto K, Muñoz DM, Andriopoulos P, Pegoraro F, Laurencikas E, Kühnle I, Wille J, Naeije L, Olkinuora H, Sinha I, Hagey DW, Olsson-Åkefeldt S, Cohen-Aubart F, Österlundh G, Svensson M, Idbaih A, Piehl F, Blennow K, Zetterberg H, von Bahr TG, Gavhed D, Morimoto A, Haroche J, Henter JI.   +29 more
europepmc   +2 more sources

Histiocytosis development and clinical variation through the lens of genomics. [PDF]

J Pathol
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Kemps PG, van Halteren AG, van Wezel T, Hogendoorn PC.   +3 more
europepmc   +2 more sources

Langerhans Cell Histiocytosis in Adults: A Canadian Multicenter Case Series. [PDF]

Hematol Oncol
ABSTRACT Langerhans cell histiocytosis (LCH) is a rare clonal myeloid neoplasm. Canadian data on clinical characteristics, molecular profile, and treatment outcomes is limited. This study aims to report the initial experience of a Canadian rare diseases program, reflecting “real‐world” diagnostic pathways, referral patterns, and treatment heterogeneity
Quon S, Gummadi Y, Elsharawi I, Dobson J, Goubran M, Stubbins RJ, Diamond EL, Chen LYC.   +7 more
europepmc   +2 more sources

Longitudinal Monocyte Subset Dynamics as Biomarker in Adult Histiocytosis: Association With Mutational Status, Kinase Inhibitor Exposure and Relapse Risk. [PDF]

Hematol Oncol
Hematological Oncology, Volume 44, Issue 5, September 2026.
Razanamahery J, Raymond C, Papo M, Pegoraro F, Guy J, Aho LS, Emile JF, Samson M, Audia S, Haroche J, Bonnotte B.   +10 more
europepmc   +2 more sources

Renovascular Hypertension: Unraveling a Case of Mixed Histiocytosis

Annals of Internal Medicine: Clinical Cases, 2023
Renovascular hypertension is a cause of secondary hypertension. Atherosclerotic renal artery stenosis and fibromuscular dysplasia are the main causes, but other rare entities can involve the renal arteries.
Pedro Marques, Joana Tender Vieira, Inês M. de Sá, André Carvalho, João Rocha-Neves, Irene Gullo, Edite Pereira, José Manuel Lopes, Jorge Almeida   +8 more
doaj   +1 more source

Adult-onset of Langerhans cell histiocytosis: a clinical case

Alʹmanah Kliničeskoj Mediciny, 2021
Langerhans cell histiocytosis is mainly diagnosed in children, and its manifestation in adult age is quite uncommon. Skin rashes may be non-specific and mimic a number of dermatoses.
Olga V. Chernysheva, Olga V. Dorokhina, Albina N. Khlebnikova, Elena V. Selezneva   +3 more
doaj   +1 more source

Adult Langerhans cell histiocytosis with a rare BRAF V600E and V600D mutation, diagnosed through oral manifestations

Advances in Oral and Maxillofacial Surgery, 2022
Langerhans cell histiocytosis, is a rare disorder characterized by an aberrant proliferation of Langerhans-type cells that infiltrates and replaces the involved tissues.
Soukaïna Oujdad, Saadia Zafad, Hicham El Attar, Ihsane Ben Yahya   +3 more
doaj   +1 more source