Results 111 to 120 of about 1,537,666 (360)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Generalized additive models to analyze non-linear trends in biomedical longitudinal data using R: Beyond repeated measures ANOVA and Linear Mixed Models [PDF]
, 2021 Ariel I. Mundo +2 more
openalex +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Revista Brasileira de Zootecnia, 2010 Records of Large White breed animals were used to estimate variance components, genetic parameters and trends for the character total number of born piglets (TNBP) as measure of litter size.
Leandro Barbosa +5 more
doaj +1 more source
Methodology of measuring performance in alternative investment [PDF]
The development of alternative investment has highlighted the limitations of standard performance measures like the Sharpe ratio, primarily because alternative strategies yield returns distributions which can be far from gaussian.
Alexis Bonnet, Isabelle Nagot
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
International Journal of Bio-Resource and Stress ManagementThe study was conducted during kharif (July, 2022–January, 2023) at the Instructional Agricultural Farm, Uttar Banga Krishi Vishwavidhyalaya, Cooch Behar, West Bengal, India to measure gene action and inheritance of yield and its attributing ...
S. Vishnupriya +8 more
doaj +1 more source
Association of SLC2A9 genotype with phenotypic variability of serum urate in pre-menopausal women
Frontiers in Genetics, 2015 The SLC2A9 gene, that encodes a renal uric acid reuptake transporter, has genetic variants that explain ~3% of variance in urate levels. There are previous reports of non-additive interaction between SLC2A9 genotype and environmental factors which ...
Ruth eTopless +6 more
doaj +1 more source
On Hoeffding and Bernstein type inequalities for sums of random variables in non-additive measure spaces and complete convergence [PDF]
, 2016 Hamzeh Agahi +2 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source