Results 81 to 90 of about 12,821,662 (251)
Generalized structured additive regression based on Bayesian P-splines [PDF]
, 2003 Generalized additive models (GAM) for modelling nonlinear effects of continuous covariates are now well established tools for the applied statistician. In this paper we develop Bayesian GAM's and extensions to generalized structured additive regression ...
Lang, S., Brezger, Andreas, Lang, Stefan
core +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Physical Review Research, 2020 We present a spectral-theoretic approach to time-average statistical mechanics for general, nonequilibrium initial conditions. We consider the statistics of bounded, local additive functionals of reversible as well as irreversible ergodic stochastic ...
Alessio Lapolla +2 more
doaj +1 more source
Dependence Measure for non-additive model
, 2013 We proposed a new statistical dependency measure called Copula Dependency Coefficient(CDC) for two sets of variables based on copula. It is robust to outliers, easy to implement, powerful and appropriate to high-dimensional variables. These properties are important in many applications.
Jiang, Hangjin, Ding, Yiming
openaire +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
How Teaching Practices Relate to Early Mathematics Competencies: A Non-Linear Modeling Perspective
Education SciencesThe significance of children’s mathematical competence during the early years is well established; however, the methods for developing such competencies remain less understood.
Yixiao Dong +3 more
doaj +1 more source
Some Fubini theorems on product sigma-algebras for non-additive measures [PDF]
We give some Fubini's theorems (interversion of the order of integration and product capacities) in the framework of the Choquet integral for product sigma-algebras. Following Ghirardato this is performed by considering slice-comonotonic functions.
Jean-Philippe Lefort, Alain Chateauneuf
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Comparison of experts in the non-additive case [PDF]
We adapt the model of comparisons of experts initiated by Lehrer («Comparison of experts JME 98») to a context of uncertainty which cannot be modelised by expected utility. We examine the robustness of Lehrer in this new context. Unlike expected utility,
Jean-Philippe Lefort
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source