Results 121 to 130 of about 140,847 (256)

A Review of the Effects of Omega-3 and Omega-6 on Alcoholic and Non-Alcoholic Fatty Liver [PDF]

Non-alcoholic fatty liver disease is a type of fatty fat that causes an increase in alcohol consumption. Excessive alcohol consumption causes inflammation, and liver damage. The certain fatty acids (FAs) may be involved in this liver damage.
Adeli, Omid-Ali, Alaa Toama, Mariam, Darvishi, Mohammad, F. Ramadan, Montather, K. Hadrawi, Salema, Majid Alsaraf, Khulood, Pirhadi, Mohadeseh   +6 more
core   +1 more source

Molecular and genetic predisposing factors of comorbidity of fatty liver disease and diseases of the colon [PDF]

, 2017
The literature review is devoted to the universal molecular markers and predictors of forming non-alcoholic fatty liver disease and pathology of the colon, the role of insulin resistance as one of the factors of the pathogenesis of non-alcoholic fatty ...
Kozlova I.V., Lapteva Е.А.
core  

Ultrasound‐Responsive Piezoelectric Membrane Promotes Osteoporotic Bone Regeneration via the “Two‐Way Regulation” Bone Homeostasis Strategy

Advanced Science, EarlyView.
Patients with osteoporosis face a higher risk of bone injury, mainly due to weakened osteogenic differentiation and bone formation, along with increased osteoclast differentiation and bone resorption activity, leading to bone homeostasis imbalance.
Xinhui Wu, Tianlong Wang, Jinhui Zhao, Lei Zhang, Zhiqing Liu, Yixing Chen, Yiping Luo, Yaqi Liu, Yan Chen, Hui Jiang, Dilixiati Duolikun, Junjian Liu, Wentao Cao, Longpo Zheng   +13 more
wiley   +1 more source

Functionalized Biomimetic Nanoparticles Targeting the IL‐10/IL‐10Rα/Glycolytic Axis in Synovial Macrophages Alleviate Cartilage Degeneration in Osteoarthritis

Advanced Science, EarlyView.
The MOF material UIO‐66‐NH2 is functionalized with DBCO groups on its surface, encapsulating NO‐prednisolone and conjugating it with azide‐modified IL‐10. Finally, the complex is extruded with MM to form biomimetic functional nanoparticles. Upon intra‐articular injection, MI@UN, enveloped by the MM, specifically targets synovial macrophages, is ...
Wenwei Li, Yang Liu, Ming Wei, Zhichao Yang, Zhaoyu Li, Zezhong Guo, Liang Yan, Yang Lu, Hao Tang, Bofeng Li, Wei Huang   +10 more
wiley   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

Non alcoholic fatty liver disease and its relationship with hsCRP in type 2 diabetes mellitus [PDF]

, 2017
Background: Diabetes mellitus is assuming an epidemic form in India. Non-alcoholic fatty liver disease worldwide is increasing too and is a major cause of liver transplant in the west.
Bhuyan, Naina, Das, Anup K., Gogoi, Mridupawan, Pegu, Ajit, Todi, Vineet   +4 more
core   +1 more source

Chinese Expert Consensus on Standardized Outpatient Management of Sarcopenia in the Elderly (2024)

AGING MEDICINE, EarlyView.
In China, specific sarcopenia clinics are not sufficient for outpatients. This consensus combines the professional advice of domestic geriatrics experts, summarizes the existing domestic experience in the establishment of sarcopenia clinics, and provides guidance for the management of sarcopenia clinics.
Zhang Qin, Kang Lin, Wang Jianye, Xi Huan, Yu Pulin, Zhang Cuntai, Hidenori Arai, Tuo Xiping, Yang Yunmei, Liu Xiaohong, Chen Chan, Chen Huaihong, Chen Xujiao, Cheng Lijuan, Deng Linzi, Ding Yi, Dong Birong, Dong Juan, Gao Yue, Gu Haifeng, Guo Yan, Han Hui, Hidenori Arai, Hu Fang, Shangcheng District, Hu Jian, Hu Yao‐min, Hu Yixin, Huang Gairong, Jian Zaijin, Jiang Wenjing, Kang Lin, Li Fuchao, Li Jian, Li Jing, Li Tianlang, Lin Fan, Liu Juan, Liu Xiaohong, Liu Xuejun, Lou Huiling, Luo Lan, Luo Man, Ma Lina, Mao Yongjun, Nie Jing, Ouyang Xiaojun, Qi Guoxian, Qiao Wei, Shi Hong, Tian Tao, Tuo Xiping, Wang Chaohui, Wang Jiaqiu, Wang Jianye, Wang Peng, Wang Quan, Wang Xiaonan, Wang Yuan, Wang Zhaodi, Wei Yanan, Wu Jun, Wu Shuhua, Wu Xiaohe, Xi Huan, Xin Xiaofeng, Xu Meiqun, Yang Yunmei, Yin Shi, Yu Plin, Zhang Cuntai, Zhang Qin, Zhang Xiaoyan, Zhang Ying, Zhao Xiaohong, Zhong Yuan, Zhou Baiyu, Zhou Houguang, Zhou Xiaohui   +78 more
wiley   +1 more source

LC‐MS and High‐Throughput Data Processing Solutions for Lipid Metabolic Tracing Using Bioorthogonal Click Chemistry

Angewandte Chemie, EarlyView.
This study introduces an integrated analytical and bioinformatics platform for high‐throughput tracing of lipid metabolism using bioorthogonal alkyne fatty acids and optimized LC‐MS workflow. Applied to human fibrosarcoma cells, the method traced fatty acid metabolism, revealing nuances in sphingolipid routing and metabolic bottlenecks, highlighting ...
Palina Nepachalovich, Stefano Bonciarelli, Gabriele Lombardi Bendoula, Jenny Desantis, Michela Eleuteri, Christoph Thiele, Laura Goracci, Maria Fedorova   +7 more
wiley   +2 more sources

Cell Membrane‐Coated Lipid Nanoparticles for Drug Delivery

Aggregate, EarlyView.
This review highlights recent progress in cell membrane‐coated lipid nanoparticles (CMC‐LNPs), focusing on their design, preparation methods, functional integration, and biomedical applications. It discusses various types of LNPs and coating strategies, characterization techniques, therapeutic functions, and applications.
Moataz B. Zewail, Guangze Yang, Yilong Fan, Yue Hui, Chun‐Xia Zhao, Yun Liu   +5 more
wiley   +1 more source

NASH: Non-Alcoholic Steatohepatitis [PDF]

, 2015
Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease which refers to the presence of hepatic steatosis without significant intake of alcohol.
Heck, Jennifer
core   +1 more source