Results 111 to 120 of about 112,073 (304)

FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis

Advanced Science, EarlyView.
ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li, Junjian Hu, Suping Hai, Peng Hu, Wenhui Wu, Qiang Gao, Binghui Yu, Feiyang Xu, Xizhe Zheng, Qianting Guan, Huiling Xiang, Dong Xi, Weiming Yan, Peng Wang, Bin‐hao Zhang, Qin Ning, Xiaojing Wang   +16 more
wiley   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

nut intake and Non-alcoholic fatty liver disease risk

, 2019
nut intake and Non-alcoholic fatty liver disease ...
Pan Xinting (8029853), Xu, Lin, Xinting, Pan, Yan Jianhui (8029856), Ying, Han, Bingbing, Chen, Li Yangfan (8029862), Peng Xian-e (8029868), Shanghua, Xu, Chen Bingbing (8029847), Lin Xu (94491), Xu Shanghua (8029865), Yangfan, Li, Wenjuan, Liu, Xian-e, Peng, Jianhui, Yan, Han Ying (8029850), Liu Wenjuan (8029859)   +17 more
core   +1 more source

Human‐Centered Innovation: Precision Nutrition and the Future of Food

Advanced Science, EarlyView.
ABSTRACT Nutritional science is moving beyond one‐size‐fits‐all recommendations toward more precise and personalized approaches, yet its implementation pathway remains unclear. This paper proposes a human‐centered precision nutrition framework that highlights the central roles of artificial intelligence (AI), food innovation, and human agency.
Shanshan Zhang, Yonggan Sun, Jiaqi Jiang, Shaoping Nie   +3 more
wiley   +1 more source

Why treat non-alcoholic fatty liver disease?

, 2013
The article considers the problem of non-alcoholic fatty liver disease, analyzes the main etiopathogenic aspects and risk factors such as obesity, insulin resistance and other.
Y. P. Uspenskiy, I. G. Pakhomova
core   +1 more source

Sex-specific effect of dietary fatty acids on non-alcoholic fatty liver disease

Frontiers in Nutrition
BackgroundNon-alcoholic fatty liver disease is the most common chronic hepatic disease worldwide. Dietary fatty acid is tightly associated with the development of non-alcoholic fatty liver disease but few large-scale and in-depth clinical researches have
Jianhua Chen, Zeqin Zhang, Yuning Pan, Jiejun Shi   +3 more
doaj   +1 more source

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

Glycosyltransferases and non-alcoholic fatty liver disease

World Journal of Gastroenterology, 2016
Non-alcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease and its incidence is increasing worldwide. However, the underlying mechanisms leading to the development of NAFLD are still not fully understood. Glycosyltransferases (GTs) are a diverse class of enzymes involved in catalyzing the transfer of one or multiple ...
Yu-Tao, Zhan, Hai-Ying, Su, Wei, An
openaire   +2 more sources

Application of artificial intelligence techniques for non-alcoholic fatty liver disease diagnosis: A systematic review (2005–2023)

Background and objectives Non-alcoholic fatty liver disease (NAFLD) is a common liver disease with a rapidly growing incidence worldwide. For prognostication and therapeutic decisions, it is important to distinguish the pathological stages of NAFLD ...
Tabesh, M., Hatami, B., Dehghan, P., Acharya, U. Rajendra, Zamanian, H., Shalbaf, A., Zali, M.R., Khalaj, A.R., Tan, Ru-San, Alizadehsani, R.   +9 more
core   +1 more source

Characterization of the gut mycobiome in patients with non-alcoholic fatty liver disease and correlations with serum metabolome

BMC Microbiology
Background Emerging evidence suggests that the gut microbiome plays a key role in metabolic diseases such as non-alcoholic fatty liver disease, yet the contribution of the gut mycobiome remains largely overlooked.
Ning Zheng, Dangrang Wang, Guorui Xing, Yidan Gao, Shenghui Li, Jin Liu, Jian Kang, Shanshan Sha, Lin Cheng, Shao Fan, Jian Yu, Qiulong Yan, Chunmeng Jiang   +12 more
doaj   +1 more source