Results 11 to 20 of about 15,109,420 (166)

Autophagy in non-alcoholic fatty liver disease and alcoholic liver disease [PDF]

Liver Research, 2018
Autophagy is an evolutionarily conserved intracellular degradative function that is important for liver homeostasis. Accumulating evidence suggests that autophagy is deregulated during the progression and development of alcoholic and non-alcoholic liver ...
Bilon Khambu, Shengmin Yan, Nazmul Huda, Gang Liu, Xiao-Ming Yin   +4 more
doaj   +2 more sources

Non-alcoholic fatty liver disease: Immunological mechanisms and current treatments. [PDF]

, 2023
Non-alcoholic fatty liver disease (NAFLD) causes significant global disease burden and is a leading cause of mortality. NAFLD induces a myriad of aberrant changes in hepatocytes at both the cellular and molecular level.
Petagine, Lucy, Patel, Vinood B, Zariwala, Mohammed Gulrez   +2 more
core   +1 more source

Elevated endotoxin levels in non-alcoholic fatty liver disease [PDF]

, 2010
Background: Emerging data indicate that gut-derived endotoxin may contribute to low-grade systemic inflammation in insulin resistant states. This study aimed to examine the importance of serum endotoxin and inflammatory markers in non-alcoholic fatty ...
Ashour, E., Steven J Creely, Youssef-Elabd, E., Youssef-Elabd, Elham M., Harte, A., Abdalla, M., Creely, S., Ashour Esmat, da Silva, Nancy F., McTernan Philip G, Mohga S Abdalla, Day, C.P., Day, Christopher Paul, Billyard, T., Burt, Alastair D., Burt Alastair D, Philip G McTernan, Kumar, S., Elham M Youssef-Elabd, da Silva, N.F., Alison L Harte, Burt, A.D., Nancy F da Silva, Amin, Ashraf I., Tripathi, Gyanendra, Sharada, H., Burt, A., McTernan, P. G., Billyard, Thomas, da Silva, N., Harte, A.L., Day Christopher P, Youssef-Elabd Elham M, Tripathi Gyanendra, Alastair D Burt, Sharada, Hayat M., Hayat M Sharada, Kumar Sudhesh, Abdalla Mohga S, Sharada, H.M., Day, C., Abdalla, Mohga S., Sudhesh Kumar, Creely, S.J., McGee Kirsty C, Esmat Ashour, McTernan, P., Abdalla, M.S., Tripathi, G., McGee, K.C., Youssef-Elabd, E.M., Kirsty C McGee, Christopher P Day, Ashour, Esmat, McGee, K., Billyard Thomas, Gyanendra Tripathi, Thomas Billyard, Kumar, Sudhesh, Amin Ashraf I, Amin, A., da Silva Nancy F, Harte, A. L., Ashraf I Amin, McTernan, P.G., Creely, Steven J., McGee, K. C., Harte Alison L, Creely Steven J, Sharada Hayat M, Amin, A.I.   +70 more
core   +1 more source

Insulin sensitisers in the treatment of non-alcoholic fatty liver disease : a systematic review [PDF]

, 2011
Non-alcoholic fatty liver disease (NAFLD) is closely linked with obesity and the prevalence of NAFLD is about 17% to 33% in the Western world. There is a strong association of NAFLD with insulin resistance and, hence, insulin sensitisers have been tried.
C Clar, Henderson, R., Gurung, T., N Waugh, N Sattar, N Ghouri, Clar, C., Sattar, Naveed, Sattar, N., Fraser, A., T Gurung, Gurung, T. (Tara), D Shyangdan, A Fraser, Shyangdan, D., D Preiss, Waugh, Norman, Shyangdan, D. (Deepson), R Henderson, Ghouri, N., Preiss, D., Waugh, N.   +21 more
core   +1 more source

Non-alcoholic fatty liver disease: a global concern

, 2022
Liver disease is a worldwide issue with death rates exponentially increasing over the last 50 years. Although there are many underlying aetiologies, one of the top three causes of liver disease is non-alcoholic fatty liver disease (NAFLD), which is an ...
Mortimore, G.
core   +1 more source

The association of vitamin D deficiency with non-alcoholic fatty liver disease

Clinics, 2014
OBJECTIVE: Vitamin D deficiency has been related to diabetes, hypertension, hyperlipidemia and peripheral vascular disease. In this study, we aimed to investigate the role of vitamin D status in non-alcoholic fatty liver disease.
Metin Küçükazman, Naim Ata, Kür?at Dal, Abdullah Özgür Yeniova, Ay?e Kefeli, Sebahat Basyigit, Bora Aktas, Kadir Okhan Akin, Kadir A?ladio?lu, Öznur Sari Üre, Firdes Topal, Ya?ar Nazligül, Esin Beyan, Derun Taner Ertugrul   +13 more
doaj   +1 more source

An Exploration of the Treatment of Non-Alcoholic Fatty Liver Disease Based on Dietary Factors [PDF]

BIO Web of Conferences
Non-alcoholic fatty liver disease is a clinical pathological syndrome characterized by diffuse hepatocellular macrovesicular steatosis caused by other liver-damaging factors except for alcohol.
Yang Wanzhou
doaj   +1 more source

Adipokines and redox signaling: impact on fatty liver disease. [PDF]

, 2011
Adipokines (adipose tissue cytokines) are polypeptide factors secreted by adipose tissue in a highly regulated manner. The 'classical' adipokines (leptin, adiponectin, and resistin) are expressed only by adipocytes, but other adipokines have been shown ...
Marra, Fabio., Parola, Maurizio, Parola, Maurizio.   +2 more
core   +1 more source

Management of non-alcoholic fatty liver disease incidentally detected during other medical assessments

, 2023
Elevated liver enzyme levels are a frequent incidental finding in primary care, and non-alcoholic fatty liver disease is the main cause of incidental elevation of liver enzymes worldwide.
Yeong Yeh Lee, Vincent Tee
core   +1 more source

Primary care and referring physician perspectives on non-alcoholic fatty liver disease management: a nationwide survey

Therapeutic Advances in Gastroenterology, 2021
Introduction: The optimal approach to screening and risk stratification for non-alcoholic fatty liver disease is challenging given disease burden and variable progression. The aim of this study was to assess primary care physician and referring physician
Naba Saeed, Lisa M. Glass, Heba Habbal, Asad Mahmood, David Sengstock, Sameer D. Saini, Monica A. Tincopa   +6 more
doaj   +1 more source