Results 71 to 80 of about 187,113 (345)

Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment

Aging and Cancer, EarlyView.
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey, Murilo Ramos Rocha, Cheyenne Palm, Vania Wang, Denys Balandin, Ethan Black, Kevin Y. Zhang, Fan Huang, Daniel J. Zabransky, Yash Chhabra, Mareike Peters, Gabriel Ghiaur, Ashani Weeraratna   +12 more
wiley   +1 more source

Non-alcoholic fatty liver disease connections with fat-free tissues: A focus on bone and skeletal muscle [PDF]

, 2017
The estimates of global incidence and prevalence of non-alcoholic fatty liver disease (NAFLD) are worrisome, due to the parallel burden of obesity and its metabolic complications. Indeed, excess adiposity and insulin resistance represent two of the major
Chiesa, Claudio, Donini, Lorenzo Maria, Lenzi, Andrea, Pacifico, Lucia, Poggiogalle, Eleonora   +4 more
core   +2 more sources

Clinical Conditions Associated With a High Antinuclear Antibody Titer in Individuals Without Autoimmune Disease

Arthritis Care &Research, EarlyView.
Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung, John P. Shelley, Gul Karakoc, John Still, Xiaodi Ruan, Jonathan Mosley, C. Michael Stein, Vivian K. Kawai   +7 more
wiley   +1 more source

Association between smoking and non-alcoholic fatty liver disease: A systematic review and meta-analysis

SAGE Open Medicine, 2018
Background/aims: Non-alcoholic fatty liver disease is one of the most common chronic liver diseases. Some risk factors are known to influence the development of non-alcoholic fatty liver disease, but the effect of tobacco smoking on the progression of ...
Arash Akhavan Rezayat, Malihe Dadgar Moghadam, Mohammad Ghasemi Nour, Matin Shirazinia, Hamidreza Ghodsi, Mohammad Reza Rouhbakhsh Zahmatkesh, Mitra Tavakolizadeh Noghabi, Benyamin Hoseini, Kambiz Akhavan Rezayat   +8 more
doaj   +1 more source

Frequency and risk factors of non-alcoholic fatty liver disease in -infected dyspeptic patients: A cross-sectional study

SAGE Open Medicine, 2021
Background: In dyspeptic patients with Helicobacter pylori contributes to non-alcoholic fatty liver disease. However, little evidence available from Pakistan.
Basit Siddiqui, Muhammad Kamran, Shiyam Sunder Tikmani, Rabeea Azmat, Zain Mushtaq, Saad Bin Zafar, Muhammad Tahir Khan, Javed Yakoob, Zaigham Abbas   +8 more
doaj   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

The cytochrome p450 epoxygenase pathway regulates the hepatic inflammatory response in fatty liver disease [PDF]

, 2014
Fatty liver disease is an emerging public health problem without effective therapies, and chronic hepatic inflammation is a key pathologic mediator in its progression.
DeGraff, LM, Edin, ML, Gruzdev, A, Huang, L, Jones, HM, Lee, CR, Lih, FB, Makowski, L, Miller, TM, Poloyac, SM, Schuck, RN, Tomer, KB, Vendrov, KC, Xu, Z, Zeldin, DC, Zha, W   +15 more
core   +4 more sources

Smart, Bio‐Inspired Polymers and Bio‐Based Molecules Modified by Zwitterionic Motifs to Design Next‐Generation Materials for Medical Applications

Advanced Functional Materials, EarlyView.
Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz, Jonas De Breuck, Sahar Salehi, Meike N. Leiske   +3 more
wiley   +1 more source

Non-alcoholic fatty liver disease: a heterogeneous phenotype. Pleiotropic effects of ursodeoxycholic acid

Лечащий Врач, 2023
Background. Non-alcoholic fatty liver disease occupies a leading position among the causes of diffuse liver diseases, both in Russia and in the world, while there is a steady upward trend in the incidence, especially in the cohort of patients with ...
E. A. Ljaljukova
doaj   +1 more source

Pediatric Non-Alcoholic Fatty Liver Disease.

Journal of medical biochemistry, 2015
The rapidly increasing prevalence of childhood obesity and its associated co-morbidities such as hypertriglyceridemia, hyper-insulinemia, hypertension, early atherosclerosis, metabolic syndrome, and non-alcoholic fatty liver disease are major public health concerns in many countries.
Delvin Edgard, Patey Natasha, Dubois Josée, Henderson Melanie, Lévy Émile   +4 more
openaire   +3 more sources