Results 131 to 140 of about 81,538 (273)

Postoperative association between impaired renal function and vascular dysfunction in liver transplant recipients

open access: yes, 2022
Liver Transplantation, EarlyView.
Domenico A. Chavez   +8 more
wiley   +1 more source

[Non-alcoholic steatohepatitis].

open access: yesTidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2001
There is a growing interest in nonalcoholic steatohepatitis (NASH), a disease entity which is quite similar to alcoholic liver disease.We present three patients with nonalcoholic steatohepatitis, and review current opinion on this disease entity.Non-alcoholic steatohepatitis is very often associated with the insulin resistance syndrome.
J W, Haukeland   +3 more
openaire   +3 more sources

Insulin‐like growth factor‐1 is inversely associated with liver fibrotic markers in patients with type 2 diabetes mellitus

open access: yesJournal of Diabetes Investigation, 2019
Aims/Introduction Insulin‐like growth factor‐1 (IGF‐1) regulates mitochondrial function, oxidative stress, inflammation, stellate cells and insulin sensitivity in the liver, and it might be associated with liver fibrosis from non‐alcoholic ...
Shozo Miyauchi   +9 more
doaj   +1 more source

Immunoglobulin A and liver diseases. [PDF]

open access: yes, 2017
Immunoglobulin A (IgA) is a major immunoglobulin isotype in the gut and plays a role in maintenance of gut homeostasis. Secretory IgA (SIgA) has multiple functions in the gut, such as to regulate microbiota composition, to protect intestinal epithelium ...
Inamine, Tatsuo, Schnabl, Bernd
core   +2 more sources

Quantitative Systems Toxicology Modeling with DILIsym to Support Phase 3 Dose Selection for Fezolinetant

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Fezolinetant is a first‐in‐class, selective, non‐hormonal, neurokinin 3 receptor antagonist that is approved for the treatment of moderate to severe vasomotor symptoms due to menopause. In a phase 2b clinical study (n = 352), nine study participants experienced elevations in serum transaminases exceeding three times the upper limit of normal.
Jace C. Nielsen   +11 more
wiley   +1 more source

Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease [PDF]

open access: yes, 2019
Snacks combining different functional ingredients could represent a useful therapeutic strategy against NAFLD. The present study aimed to analyze the effect of two snack formulations based on carob and wakame flour in the treatment for NAFLD in rats. For
Aguirre López, Leixuri   +6 more
core   +2 more sources

Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?

open access: yesJournal of Translational Medicine, 2008
Background Inside the spectrum of non-alcoholic fatty liver disease, simple fatty liver is generally thought of as being "non progressive", differently from non-alcoholic steatohepatitis, which increases in severity due to the presence of apoptosis ...
Contaldo Franco   +9 more
doaj   +1 more source

Hepatic Steatosis and Steatohepatitis Is the Inevitability of Mixed Genesis

open access: yesGastroenterologìa, 2014
The analysis of the etiological and pathogenetic mechanisms of formation steatosis and steatohepatitis of mixed genesis is presented. It is shown that alcohol remains one of the main etiopathogenetic factors in the development of the hepatic steatosis ...
Yu.M. Stepanov
doaj   +1 more source

PARP inhibition protects against alcoholic and non-alcoholic steatohepatitis [PDF]

open access: yes, 2018
K
Auwerx, Johan   +22 more
core  

Genetic and Epigenetic Regulation in Nonalcoholic Fatty Liver Disease (NAFLD) [PDF]

open access: yes, 2018
Genetics and epigenetics play a key role in the development of several diseases, including nonalcoholic fatty liver disease (NAFLD). Family studies demonstrate that first degree relatives of patients with NAFLD are at a much higher risk of the disease ...
Campo, José Antonio del   +3 more
core   +2 more sources

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