Results 131 to 140 of about 64,153 (235)
Low‐Irradiance Antimicrobial Blue Light‐Bathing Therapy for Wound Infection Control
Advanced Science, EarlyView.Antimicrobial blue light has been shown as an appealing non‐pharmacological antimicrobial alternative. However, its clinical applications have been hindered by high irradiance‐associated photothermal risks. In this work, a low‐irradiance blue light‐bathing concept and a wearable photonic wound patch are established to address this challenge in terms of
Jie Hui +12 more
wiley +1 more source
Angewandte Chemie International Edition, Volume 61, Issue 51, December 19, 2022., 2022 Corramycin is a novel natural product produced by the myxobacterium Corallococcus coralloides. The structure, extraordinary total synthesis and biosynthesis of the antibiotic is described for the first time. Its promise as an in vivo septicemia model, the absence of cross‐resistance with commonly used antibiotic classes, and the lack of cytotoxicity ...
Cédric Couturier +32 more
wiley +1 more source
Advanced Science, EarlyView.A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim +6 more
wiley +1 more source
The Role of Cytochrome P450 AbyV in the Final Stages of Abyssomicin C Biosynthesis
Angewandte Chemie International Edition, Volume 62, Issue 3, January 16, 2023., 2023 The cytochrome P450 enzyme AbyV catalyses a key epoxidation in the final stages of the biosynthesis of the spirotetronate antibiotic abyssomicin C. Combining structural and computational data with a 13C labelling strategy was found to be a powerful approach to interrogate the biotransformation and determine the precise function of the enzyme.
Andrew J. Devine +13 more
wiley +1 more source
Non-aureus staphylococci and mammaliicocci isolated from dairy cow milk and their relationships with the presence of mastitis: a retrospective investigation [PDF]
, 2023 Maria Filippa Addis +10 more
openalex +1 more source
Advanced Science, EarlyView.The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He +6 more
wiley +1 more source
Etiological Agents of Health-care associated Surgical Site Infections [PDF]
Bioautomation, 2007 Surgical site infection is the second most common nosocomial (health-care associated) infection among hospitalized patients and is a significant public health problem worldwide.
Rita Treimane +2 more
doaj
Investigating the metabolism of non-aureus staphylococci relevant to prosthetic joint infection
, 2020 Prosthetic joint infection (PJI) is a complication of joint replacement that occurs when bacteria adhere to the surface of a prosthetic joint and form a biofilm (Becker et al. 2014; Tande et al. 2014). Treatment is expensive and aggressive, constituting a major burden to the healthcare system and to the patients (Becker et al. 2014; Tande et al. 2014).
openaire +1 more source
Advanced Science, EarlyView.This study demonstrates that the atypical dehydrogenase/isomerase FabX in Type‐II fatty acid biosynthesis pathway is essential for H. pylori infection by retaining unsaturated fatty acid synthesis and producing superoxide (ROS). A small molecule FBX‐1991 that specifically targets FabX to inhibit H.
Lin Zhang +9 more
wiley +1 more source
Advanced Science, EarlyView.Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang +10 more
wiley +1 more source