Results 111 to 120 of about 36,545 (260)

Evolutionary trade-offs underlie the multi-faceted virulence of Staphylococcus aureus

, 2015
Date of Acceptance: 20/07/2015Bacterial virulence is a multifaceted trait where the interactions between pathogen and host factors affect the severity and outcome of the infection. Toxin secretion is central to the biology of many bacterial pathogens and
Williams, Barnabas, Uhlemann, Anne-Catrin, Edward Feil, Recker, Mario, Maisem Laabei (311431), Lowy, FD, Clarke, SR, Janina Dordel (250569), Janina Dordel, Votintseva, Antonina A., Lowy, Franklin D., Votintseva, AA, Austin, ED, Wilson, Daniel J, Bowden, Rory, Wilson, Daniel J., Daniel J. Wilson (194149), Matthew Holden, Crook, Derrick W., Dordel, Janina, Derrick W Crook, Maho Yokoyama (791513), Thorpe, Harry A, Holden, Matthew, Matthew Holden (791517), Sharon J. Peacock (35782), Derrick W. Crook (145636), Austin, Eloise D, Williams, B, Mario Recker (88496), Sharon J Peacock, Eloise D Austin, Perkins, Mark, Votintseva, Antonina A, Barnabas Williams (791515), Recker, M, Mario Recker, Franklin D Lowy, Young, Bernadette C, Khadija Ouadi, Ouadi, Khadija, Eloise D. Austin (791512), Rory Bowden (179995), Crook, Derrick, Wilson, DJ, Barnabas Williams, Bernadette C Young, Maho Yokoyama, Yokoyama, Maho, Clark, Stephen Robert, Harry A Thorpe, Franklin D. Lowy (299074), Uhlemann, AC, Feil, E, Edward Feil (270047), Anne-Catrin Uhlemann, Stephen R Clarke, Ouadi, K, Antonina A Votintseva, Clarke, Stephen R, Peacock, Sharon J., Mark Perkins, Peacock, SJ, Laabei, M, Ruth C. Massey (174217), Maisem Laabei, Antonina A. Votintseva (791518), Harry A. Thorpe (791514), Austin, Eloise D., Young, BC, Peacock, Sharon J, Massey, Ruth C., Mark Perkins (254177), Bernadette C. Young (408943), Massey, RC, Crook, DW, Thorpe, HA, Clarke, Stephen R., Feil, Edward, Anne-Catrin Uhlemann (299063), Wilson, Daniel, Crook, Derrick W, Laabei, Maisem, Khadija Ouadi (598087), Perkins, M, Lowy, Franklin D, Daniel J Wilson, Rory Bowden, Stephen R. Clarke (791516), Bowden, R, Dordel, J, Massey, Ruth C, Young, Bernadette C., Thorpe, Harry A., Yokoyama, M, Holden, M, Ruth C Massey   +96 more
core   +1 more source

Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse

Advanced Science, EarlyView.
We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang, Yali Chang, Zibin Chu, Linghao Zhang, Tengfang Zhang, Dai Erhei, Xin Su, Zhe Yin   +7 more
wiley   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source

Oral Motion‐Powered Smart Dental Implant Abutment for In Situ Antibacterial and Cell Adhesion Through Piezoelectric Effect

Advanced Science, EarlyView.
We proposed a method based on the piezoelectric effect and fabricated an implant abutment on the basis of piezoelectric ceramic. Under physiological occlusal pressure, the oral motion‐powered smart dental implant abutments interacted with water and oxygen, promoting the formation of reactive oxygen species and achieving a synergistic and highly ...
Xiyu Shi, Xiaoyu Han, Yanhui Lu, Yuan Chai, Baiyan Xiao, Shuo Liu, Boon Chin Heng, Tingting Wu, Tingjun Li, Qiaomei Ren, Ting Song, Le Chen, Dong Han, Yaru Guo, Xuliang Deng, Xuehui Zhang   +15 more
wiley   +1 more source

Antibiotic Resistance Pattern of Isolated Strains of Staphylococcus Aureus from Personnel Nasal Specimens in Meshgin Shahr Valiasr Hospita [PDF]

Background & Objectives: Staphylococcus aureus is known as an important pathogen causing a variety of bacterial infections. Treatment of this bacterium with antibiotics has led to antibiotic-resistancy, especially against methicillin (MRSA) and more ...
کریم وند, نسیم, نيك بخت, مجتبي, حسن نژاد, سيامك, فرجي, فاطمه, رضازاده, بابك, قرباني, فياض, نقی زاده باقی, عباس   +6 more
core  

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

The identification and characterization of a clinical isolate of a methicillin susceptible Staphylococcus aureus ST612

, 2012
Includes bibliographical references.A previous study of 100 methicillin-resistant Staphylococcus aureus (MRSA) isolates, collected between January 2007 and December 2008 from five Cape Town hospitals, identified ST612-MRSA-IV as the predominant MRSA ...
Moleleki, Malefu
core  

Crystal Facet‐Polysaccharide Matching in CFS‐P Nanocrystals Drives Fungal Uptake, Vacuole Destruction, and Selective Antifungal Activity

Advanced Science, EarlyView.
Facet‐engineered PVP‐capped CuFeSe2 nanocrystals exhibit potent, selective antifungal activity by strongly binding cell‐wall mannan, enabling vacuolar entry and organelle disruption. High‐index facets show superior mannan affinity, validated by theoretical calculations and experiments. CFS‐P induces vacuolar cavitation, mitochondrial abnormalities, and
Zhaohui Wang, Xiaojin Deng, Xujuan Huang, Yuhang Pan, Yao Qin, Lu Zhang, Le Xu, Tianyi Qin, Deteng Zhang, Yi Ma, Yalong Wang   +10 more
wiley   +1 more source

A Biomimetic Lubricant Captures Hyaluronic Acid In Situ to Regenerate Cartilage: From Bench to Bedside

Advanced Science, EarlyView.
(a) The outstanding lubricative properties of natural articular cartilage arise from a composite coating composed of HA, lubricin, and phospholipids at its surface. Notably, lubricin facilitates the enrichment of synovial HA onto cartilage surfaces, and HA complexes with phospholipids, a key component to maintain extremely low friction under high ...
Yongan Lin, Zijian Yan, Jiayi Chen, Xiaochao Wang, Ruibin Lin, Yunqi Fu, Zhaoying Lv, Bohui Wu, Xuewei Cao, Renjian Xie, Ming Dong, Chenxiao Zheng, Li Ren   +12 more
wiley   +1 more source

Detection of icaA, icaD genes and biofilm production by Staphylococcus aureus and Staphylococcus epidermidis isolated from urinary tract catheterized patients

Journal of Infection in Developing Countries, 2009
Background: Staphylococci are a common cause of catheter-associated urinary tract infections. The present study evaluated biofilm forming capacity and the presence of both icaA and icaD genes among staphylococci strains isolated from patients undergoing ...
Gamal Fadl Mahmoud Gad, Mohamed Ali El-Feky, Mostafa Said El-Rehewy, Mona Amin Hassan, Hassan Abolella, Rehab Mahmoud Abd El-Baky   +5 more
doaj   +1 more source