Results 91 to 100 of about 10,217,790 (260)
Survival of Staphylococcus aureus ST398 in the human nose after artificial inoculation. [PDF]
, 2012 There is evidence that MRSA ST398 of animal origin is only capable of temporarily occupying the human nose, and it is therefore, often considered a poor human colonizer.We inoculated 16 healthy human volunteers with a mixture of the human MSSA strain ...Dep Infectieziekten Immunologie, Tavakol, M. (Mehri), Slingerland, B.C.G.C. (Bibi), Vos, M.C. (Margreet), Jodi A. Lindsay, Lindsay, J.A., Tavakol, Mehri, Slingerland, BC, van Wamel, WJ, Lindsay Jodi A., Wagenaar, J.A., Alex van Belkum (38419), Slingerland, B.C.G.C., Jaap A. Wagenaar (103922), Snijders, S.V. (Susan), Henri A. Verbrugh, Mehri Tavakol (106145), Verbrugh Henri A., Tavakol Mehri, Verbrugh, H.A. (Henri), McCarthy, A.J., Snijders, Susan, McCarthy Alex J., Jodi A. Lindsay (119622), Lindsay, JA, Willem J. B. Van Wamel, Vos, Greet, Vos, M.C., Strategic Infection Biology, Susan V Snijders, Jodi A Lindsay, Vos, Greet; id_orcid, Bibi C. G. C. Slingerland (119611), Snijders, SV, Tavakol, M, Verbrugh, H.A., Margreet C Vos, van Wamel, Willem; id_orcid, Jaap A. Wagenaar, Verbrugh, Henri, Snijders, S.V., McCarthy, A.J. (Alex), Wagenaar Jaap A., Advances in Veterinary Medicine, Mehri Tavakol, Slingerland Bibi C. G. C., Verbrugh, HA, Wagenaar, J.A. (Jaap), van Belkum Alex, van Wamel Willem J. B., Alex J. Mccarthy, Susan V. Snijders (106138), Bibi C. G. C. Slingerl, Lindsay, J.A. (Jodi), Henri A Verbrugh, Vos Margreet C., Snijders Susan V., Tavakol, M., Jaap A Wagenaar, Wagenaar, JA, Willem J. B. van Wamel (106154), Margreet C. Vos (119632), Wamel, W.J.B. (Willem) van, van Wamel, W.J., Bibi C G C Slingerland, Susan V. Snijders, Belkum, Alex, van Belkum, A, Mason - Slingerland, Bibi, Willem J B van Wamel, Vos, MC, Belkum, A.F. (Alex) van, McCarthy, AJ, Henri A. Verbrugh (106151), Margreet C. Vos, van Belkum, A., van Wamel, Willem, Alex J McCarthy, Alex van Belkum, Alex J. McCarthy (119618) +79 morecore +5 more sourcesConjugated Porphyrin Polymer With Superior Charge Transfer for Photodynamic‐Immunomodulatory Prevention of CIED Infection in Diabetes
Advanced Healthcare Materials, EarlyView.Under NIR irradiation, PTCPP generates ROS to eliminate MRSA biofilms and promote M1 macrophage polarization for phagocytosis. After bacterial clearance, the material is phagocytosed by macrophages, shifting their polarization to M2 phenotype via metabolic reprogramming, which synergistically enhances anti‐infection therapy and wound healing.Honghao Ma, Jinguo Xu, Rongrong Gu, Chuanhui Dong, Te Chen, Yi Mu, Jing Zhu, Yating Wang, Wen Wang, Yingying Zhang, Hongyu Ma, Xiaochen Wang, Sheng Ye, Cheng Cheng +13 morewiley +1 more sourceEvolutionary trade-offs underlie the multi-faceted virulence of Staphylococcus aureus [PDF]
, 2015 Date of Acceptance: 20/07/2015Bacterial virulence is a multifaceted trait where the interactions between pathogen and host factors affect the severity and outcome of the infection. Toxin secretion is central to the biology of many bacterial pathogens and Williams, Barnabas, Uhlemann, Anne-Catrin, Edward Feil, Recker, Mario, Maisem Laabei (311431), Lowy, FD, Clarke, SR, Janina Dordel (250569), Janina Dordel, Votintseva, Antonina A., Lowy, Franklin D., Votintseva, AA, Austin, ED, Wilson, Daniel J, Bowden, Rory, Wilson, Daniel J., Daniel J. Wilson (194149), Matthew Holden, Crook, Derrick W., Dordel, Janina, Derrick W Crook, Maho Yokoyama (791513), Thorpe, Harry A, Holden, Matthew, Matthew Holden (791517), Sharon J. Peacock (35782), Derrick W. Crook (145636), Austin, Eloise D, Williams, B, Mario Recker (88496), Sharon J Peacock, Eloise D Austin, Perkins, Mark, Votintseva, Antonina A, Barnabas Williams (791515), Recker, M, Mario Recker, Franklin D Lowy, Young, Bernadette C, Khadija Ouadi, Ouadi, Khadija, Eloise D. Austin (791512), Rory Bowden (179995), Crook, Derrick, Wilson, DJ, Barnabas Williams, Bernadette C Young, Maho Yokoyama, Yokoyama, Maho, Clark, Stephen Robert, Harry A Thorpe, Franklin D. Lowy (299074), Uhlemann, AC, Feil, E, Edward Feil (270047), Anne-Catrin Uhlemann, Stephen R Clarke, Ouadi, K, Antonina A Votintseva, Clarke, Stephen R, Peacock, Sharon J., Mark Perkins, Peacock, SJ, Laabei, M, Ruth C. Massey (174217), Maisem Laabei, Antonina A. Votintseva (791518), Harry A. Thorpe (791514), Austin, Eloise D., Young, BC, Peacock, Sharon J, Massey, Ruth C., Mark Perkins (254177), Bernadette C. Young (408943), Massey, RC, Crook, DW, Thorpe, HA, Clarke, Stephen R., Feil, Edward, Anne-Catrin Uhlemann (299063), Wilson, Daniel, Crook, Derrick W, Laabei, Maisem, Khadija Ouadi (598087), Perkins, M, Lowy, Franklin D, Daniel J Wilson, Rory Bowden, Stephen R. Clarke (791516), Bowden, R, Dordel, J, Massey, Ruth C, Young, Bernadette C., Thorpe, Harry A., Yokoyama, M, Holden, M, Ruth C Massey +96 morecore +1 more sourceLiving with an imperfect cell wall: compensation of femAB inactivation in Staphylococcus aureus [PDF]
, 2007 Background: Synthesis of the Staphylococcus aureus peptidoglycan pentaglycine interpeptide bridge is catalyzed by the nonribosomal peptidyl transferases FemX, FemA and FemB.Majcherczyk, Paul A, Andrea Jansen, Harris, Llinos G.,, Berger-Bächi, Brigitte, Gabriele Bierbaum, Bierbaum, Gabriele, Majcherczyk, Paul A.,, Hübscher, Judith,, Schäfer, Juliane,, Jansen Andrea, Schäfer, Juliane, Heinemann, Matthias,, Kotte, Oliver, Bierbaum Gabriele, Heinemann, Matthias; id_orcid, Harris, Llinos G., Hübscher, Judith, Bierbaum, Gabriele,, Judith Hübscher, Majcherczyk Paul A, Oliver Kotte, Jansen, Andrea,, Schäfer Juliane, Berger-Bächi, Brigitte,, Kotte, Oliver,, Jansen, Andrea, Brigitte Berger-Bächi, Llinos Harris, Heinemann, Matthias, Matthias Heinemann, Majcherczyk, Paul A., Heinemann Matthias, Harris, Llinos G, Llinos G Harris, Hübscher Judith, Juliane Schäfer, Kotte Oliver, Paul A Majcherczyk, Harris Llinos G, Berger-Bächi Brigitte +39 morecore +3 more sourcesOptical Detection of Cellular Signals at Material Interfaces
Advanced Healthcare Materials, EarlyView.Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou +5 morewiley +1 more sourcePLL‐g‐HPA Hydrogel Microneedles Loaded With Rhoifolin Target Macrophages to Alleviate Fibroblast Senescence for Diabetic Wound Healing
Advanced Healthcare Materials, EarlyView.Diabetic wound healing is hindered by a pathological crosstalk wherein elevated IL‐11 induces M1 macrophage polarization, leading to IL‐1β/IL‐6 release and subsequent fibroblast senescence via RAS/p38MAPK/p53/E2F1 signaling. Here, we develop a Gel@M‐Rho microneedle patch that delivers rhoifolin‐loaded, macrophage membrane‐coated nanoparticles to target Jiewen Liao, Lin Gan, Li Lu, Lizhi Ouyang, Yuan Xiong, Fawwaz Al‐Smadi, Guandong Dai, Mohammad‐Ali Shahbazi, Bobin Mi, Mengfei Liu, Guohui Liu +10 morewiley +1 more sourceOutcome of Bloodstream Infections Caused by Antibiotic-Resistant Bacteria: A 7-Year Retrospective Study at the University Hospital of Palermo, Italy
AntibioticsBackground: Bloodstream infections (BSIs) are both a primary cause and a severe complication of hospitalization. This retrospective study aims to analyze the epidemiology of BSIs at the University Hospital of Palermo from 2018 to 2024.Luca Pipitò, Eleonora Bono, Chiara Vincenza Mazzola, Raffaella Rubino, Antonio Anastasia, Salvatore Antonino Distefano, Alberto Firenze, Giovanni M. Giammanco, Celestino Bonura, Antonio Cascio +9 moredoaj +1 more sourceWhole-genome sequencing reveals clonal expansion of multiresistant Staphylococcus haemolyticus in European hospitals [PDF]
, 2014 Objectives Staphylococcus haemolyticus is an emerging cause of nosocomial infections, primarily affecting immunocompromised patients. A comparative genomic analysis was performed on clinical S.Kahlke, Tim, Flægstad, Trond, Jorunn Pauline Cavanagh, Matthew T. G. Holden, Tim Kahlke, Johanna U. Ericson Sollid, Holden, Matthew T G, Hjerde, Erik, Parkhill, Julian, Klingenberg, Claus, Claus Klingenberg, Cavanagh, Jorunn Pauline, Stephen D. Bentley, Erik Hjerde, Parkhill, J, Trond Flægstad, Sollid, Johanna U Ericson, Bentley, Stephen D, Julian Parkhill, Holden, Matthew T.G. +19 morecore +1 more source