Results 241 to 250 of about 24,186,788 (290)
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Resistance to Antiretroviral Agents in Individuals with HIV-1 Non-B Subtypes
HIV Clinical Trials, 2002Naturally occurring polymorphisms at positions involved in resistance to antiretroviral agents are frequently seen in HIV-1 non-B subtypes. Although they do not seem to affect significantly the susceptibility to antiretroviral drugs in vitro, they may facilitate the selection of different pathways and/or a more rapid emergence of drug resistance and ...
Africa, Holguín, Vincent, Soriano
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Susceptibility of HIV-1 non-B subtypes and recombinant variants to Enfuvirtide
Journal of Clinical Virology, 2007Data on susceptibility of HIV-1 non-B subtypes to Enfuvirtide (ENF) is rather limited.To determine if ENF could be active in vitro against HIV-1 non-B subtypes and how the gp41 genetic variability across variants may influence ENF susceptibility.Using PHENOSCRIPT Env, a recombinant envelope virus assay, ENF susceptibility was investigated in isolates ...
Africa, Holguín +3 more
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Non-B HIV-1 subtypes in sub-Saharan Africa: impact of subtype on protease inhibitor efficacy
Biological Chemistry, 2014Abstract In 2012, 25 million people [71% of global human immunodeficiency virus (HIV) infection] were estimated to be living with HIV in sub-Saharan Africa. Of these, approximately 1.6 million were new infections and 1.2 million deaths occurred. South Africa alone accounted for 31% of HIV/acquired immunodeficiency syndrome (AIDS) deaths in sub-Saharan ...
Previn, Naicker, Yasien, Sayed
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Rising Prevalence of HIV-1 Non-B Subtypes in Belgium: 1983???2001
JAIDS Journal of Acquired Immune Deficiency Syndromes, 2004This study documented the HIV-1 subtype distribution in 2 Belgian hospitals and determined predictive demographics for non-B subtypes. Overall, subtype B was the most prevalent subtype in this population, followed by subtypes A and C. Several recombinants were detected, circulating recombinants as well as new ones.
Snoeck, Joke +9 more
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Protease Gene Analysis of HIV Type 1 Non-B Subtypes in Spain
AIDS Research and Human Retroviruses, 2000The protease gene of human immunodeficiency virus type 1 (HIV-1) clinical isolates found in 15 immigrants (most of African origin) living in Spain was examined. Phylogenetic analyses were performed, taking as reference a panel of 26 HIV protease gene sequences deposited with GenBank.
A, Holguín, B, Rodés, V, Soriano
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Evidence for Onward Transmission of HIV-1 Non-B Subtype Strains in the United Kingdom
JAIDS Journal of Acquired Immune Deficiency Syndromes, 2006An increasing proportion of new HIV diagnoses in the United Kingdom and other European countries are attributable to non-B subtype infections, mainly among black Africans with infections heterosexually acquired in sub-Saharan Africa. We examined whether there was evidence for onward transmission of non-B subtypes within an ethnically diverse HIV-1 ...
Aggarwal, I. +6 more
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