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High levels of discordance between sequencing and serological subtyping in a predominantly non-B subtype HIV-1 infected cohort

Journal of Clinical Virology, 2005
Samples from 457 randomly selected HIV-1 infected patients attending King's College Hospital were analysed using a subtype specific enzyme immunoassay. All serotyped non-Bs that provided unambiguous sequence and for which sufficient sample was available (n=100), which included three serotyped subtype B samples were further analysed by env sequencing ...
Smith, M.   +4 more
openaire   +3 more sources

High Prevalence of Non-B HIV-1 Subtypes in Overseas Sailors and Prostitutes in Korea

AIDS Research and Human Retroviruses, 2018
There have been no studies related to groups at the highest risk for HIV-1 infection in Korea before 1993. In this study, for the first time, we report the distribution of HIV subtypes in overseas sailors (OSs) and prostitutes who worked in brothels near U.S. military bases in Korea.
Young-Keol, Cho   +2 more
openaire   +2 more sources

HIV-1 Genetic Diversity in Northeastern Brazil: High Prevalence of Non-B Subtypes

AIDS Research and Human Retroviruses, 2017
The Northeastern Brazilian region has experienced a constant increase in the number of newly reported AIDS cases over the last decade, but the genetic diversity of HIV-1 strains currently disseminated in this region remains poorly explored. HIV-1 pol sequences were obtained from 140 patients followed at outpatient clinics from four Northeastern ...
Edson, Delatorre   +2 more
openaire   +2 more sources

Introduction of HIV type 1 non‐B subtypes into Eastern Andalusia through immigration

Journal of Medical Virology, 2003
AbstractA study of the distribution of HIV‐1 subtypes in the native and immigrant populations of Eastern Andalusia (Southern Spain) was conducted to determine any changes between 1983 and 2001 and to identify antiretroviral resistance mutations in non‐B subtype strains among the immigrant population.
Marta, Alvarez   +7 more
openaire   +2 more sources

Molecular Characterization of Non-B HIV Type 1 Subtypes from Africa in Spain

AIDS Research and Human Retroviruses, 2000
All of the known HIV-1 subtypes are present in sub-Saharan Africa. The B subtype is predominant in the United States and Europe, but previous studies have revealed that other subtypes are also in circulation. We report here on the genetic characterization of eight non-B subtype VIH-1 virus strains detected during 1999 in patients living in Spain and ...
M, Ortiz   +8 more
openaire   +2 more sources

[Diagnosis of HIV-1 non-B subtypes and HIV-2].

Enfermedades infecciosas y microbiologia clinica, 2009
The high genetic diversity of human immunodeficiency virus (HIV) poses a significant challenge to the diagnosis and microbiological characterization of HIV infection. Because of the continual emergence of new variants and the global spread of HIV groups, subtypes and recombinant forms, accurate diagnostic tools are of prime importance.
Carlos, Toro   +2 more
openaire   +1 more source

The impact of immigration on env HIV-1 subtype distribution among heterosexuals in the Netherlands: influx of subtype B and non-B strains

AIDS, 2001
To examine the epidemiological factors influencing the distribution and spread of HIV-1 subtypes among heterosexuals in the Netherlands.A nationwide serosurveillance in 21 HIV/AIDS centres from 1997 to 1999 involved 200 individuals for whom the mode of HIV transmission was heterosexual contact or unknown.
Op de Coul, E. L.   +6 more
openaire   +3 more sources

Evaluation of three rapid tests for detection of antibodies to HIV-1 non-B subtypes

Journal of Virological Methods, 2004
Three rapid tests were evaluated for the detection of antibodies to HIV in 111 plasma specimens (81 HIV-1 non-B subtypes, including 4 coinfections with HIV-2, 30 HIV negative). The Determine HIV-1/2, Equipar HIV, and Multispot HIV-1/2 tests were 100% sensitive and specific for the detection of HIV-1 antibodies.
openaire   +2 more sources

The SnoB study: frequency of baseline raltegravir resistance mutations prevalence in different non-B subtypes

Medical Microbiology and Immunology, 2011
The SnoB study analysed the variability of the integrase (IN) gene of non-B viruses from treatment-naïve patients to determine whether non-B subtypes carry natural resistance mutations to raltegravir (RAL). Plasma viral RNA from 427 patients was gained, and IN sequences were subtyped and screened for subtype-specific highly-variable residues.
Sierra, Saleta   +10 more
openaire   +2 more sources

Genetic and Phylogenetic Characterization of Structural Genes from Non-B HIV-1 Subtypes in Italy

AIDS Research and Human Retroviruses, 2006
A molecular and phylogenetic characterization on env and gag subgenomic regions has been performed in our laboratory on HIV-1 variants identified in seropositive individuals residing in Italy, infected in the 1999-2001 period, and five non-B-subtype HIV-1 isolates have been described.
M, Tagliamonte   +5 more
openaire   +2 more sources

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