Results 191 to 200 of about 963,524 (371)

About Non – Coding Rnas

, 2018
Abstract— The central dogma of molecular biology states that DNA makes RNA and RNA makes protein. Recently, a large number of RNAs have been identified in animal and plants that have little or no protein – coding potential. Such RNA molecules have been discovered by the extensive applications of high – throughput sequencing technology.
openaire   +2 more sources

Non-coding RNAs and exosomal non-coding RNAs in lung cancer: insights into their functions

Frontiers in Cell and Developmental Biology
Lung cancer is the second most common form of cancer worldwide Research points to the pivotal role of non-coding RNAs (ncRNAs) in controlling and managing the pathology by controlling essential pathways. ncRNAs have all been identified as being either up- or downregulated among individuals suffering from lung cancer thus hinting that they may play a ...
Xiaolong Lv, Lei Yang, Yunbo Xie, Mohammad Reza Momeni   +3 more
openaire   +3 more sources

An RNA condensate model for the origin of life [PDF]

arXiv
The RNA World hypothesis predicts that self-replicating RNAs evolved before DNA genomes and coded proteins. Despite widespread support for the RNA World, self-replicating RNAs have yet to be identified in a natural context, leaving a key 'missing link' for this explanation of the origin of life.
arxiv  

Nucleotide Sequences of 5' and 3' Non-coding Regions of Pepper Mild Mottle Virus Strain S RNA

, 1989
M.J. Avila-Rincon, Maxime Ferrero, E. Alonso, Isabel Garcı́a, J. R. Díaz-Ruíz   +4 more
openalex   +1 more source

The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function [PDF]

, 2007
Camilla Schéele, Nataša Petrović, Mohammad Ali Faghihi, Timo Lassmann, Katarina Fredriksson, Olav Rooyackers, Claes Wahlestedt, Liam Good, James A. Timmons   +8 more
openalex   +1 more source

Comparative single‐cell transcriptomic profiling of patient‐derived renal carcinoma cells in cellular and animal models of kidney cancer

FEBS Open Bio, EarlyView.
We generated and characterized clear cell renal cell carcinoma models using the patient‐derived RCC243 cell line—including cell culture, orthotopic, and metastatic tumors—via single‐cell RNA‐sequencing for comparisons between models and patient tumor datasets.
Richard Huang, Lynn Kee, Alexander Gont, Jalna Meens, Fraser G. Ferens, Meredith S. Irwin, Laurie Ailles, Scott A. Yuzwa, Claire M. Robinson, Michael Ohh   +9 more
wiley   +1 more source

Bunyavirus Nucleoprotein, N, and a Non-structural Protein, NSS, Are Coded by Overlapping Reading Frames in the S RNA

, 1983
Frederick J. Fuller, Ajit S. Bhown, D. H. L. Bishop   +2 more
openalex   +1 more source

Multiple alignment and structure prediction of non-coding RNA sequences [PDF]

, 2007
Stinus Lindgreen, Paul P. Gardner, Anders Krogh   +2 more
openalex   +1 more source

The functions and unique features of long intergenic non-coding RNA

Nature reviews. Molecular cell biology, 2017
J. Ransohoff, Yuning Wei, P. Khavari
semanticscholar   +1 more source

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source