Results 301 to 310 of about 1,318,082 (335)

Physical Adsorption‐Driven Assembly of Au‐Locked Nucleic Acid (LNA) Probes on MoS2 Nanosheets for SERS‐Based Detection of microRNAs (miRNAs)

Advanced Materials Interfaces, EarlyView.
The Au‐LNA Raman probe, composed of gold nanoparticles (AuNPs), thiol functional group, and Cy3 modified LNAs, synthesized after hybridization of LNA and miR‐210‐3p target, is integrated into the MoS2@Au composite. The integration of the nanocomposite is formed by physical adsorption of Au‐LNA nanohybrid with MoS2. Characterization confirms morphology,
Faith Mokobi Zablon, Md. Arifur Rahman Khan, Tetyana Ignatova, Kristen Dellinger, Shyam Aravamudhan   +4 more
wiley   +1 more source

Comprehensive identification of proteins interacting with long non-coding RNA TUG1 in R-loop regulation. [PDF]

J Biochem
Xie J, Suzuki MM, Iijima K, Shinjo K, Nishimura T, Watanabe S, Nakagawa R, Ito T, Kondo Y.   +8 more
europepmc   +1 more source

Damage Microenvironment Guided Responsive Smart Hydrogel Design for Self‐Regenerative Repair in Chronic Wound Healing

Advanced Materials Interfaces, EarlyView.
Chronic wounds remain a major therapeutic challenge, with VEGF applications hindered by rapid degradation and systemic side effects. Here, a dual‐responsive chitosan–gelatin hydrogel is reported, functionalized with dopamine, glutathione, and MMP‐sensitive motifs, enabling spatiotemporally controlled VEGF release and enhanced biocompatibility, thereby ...
Zhenghui Xiong, Guangzheng Han, Kai Zheng, Yin Gong, Yida Chen, Zili Ge   +5 more
wiley   +1 more source

Mapping the non-coding RNA landscape in ataxia telangiectasia: a scoping review of ATM dependent miRNA and lncRNA dysregulation. [PDF]

Mol Biol Rep
Iqbal MJ, Ameen U, Tanveer H, Israr L, Ricci A, Morganti G, Khan MJ, Menotta M.   +7 more
europepmc   +1 more source

Biogenic Next‐Gen CPL Emitters: Strategies with Proteins, Polysaccharides, and Nucleotides

Advanced Optical Materials, EarlyView.
Biogenic molecules such as proteins, peptides, saccharides, and DNA can act as natural scaffolds for generating circularly polarized luminescence (CPL). This review highlights recent strategies exploiting these inherently chiral frameworks to achieve light emission with controllable handedness under unpolarized excitation, bridging biological ...
Ricardo Chavez‐Jimenez, Gustavo González‐Gaitano, Julio Fernandez‐Cestau, Mattia Nieddu, Juan Pablo Fuenzalida‐Werner   +4 more
wiley   +1 more source

Precision Diagnostics in Sports‐Related Traumatic Brain Injury: Pathophysiology, Biomarker Development and Emerging Technologies

Advanced Sensor Research, EarlyView.
Sports‐related traumatic brain injuries (TBIs) remain underdiagnosed, within amateur athletic cohorts. This review critically synthesises recent advancements in AI‐assisted neuroimaging, blood‐based biomarker profiling, wearable biosensing platforms for early detection, injury stratification, and longitudinal surveillance of TBIs.
Daniel Nicol, Mohamed T. Patel, Debarati Bhowmik, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

The Impact of Non-Coding RNA on Inflammation and Airway Remodeling in Asthma Related to Obesity: State-of-the-Art and Therapeutic Perspectives. [PDF]

J Clin Med
Kachel M, Langwiński W, Szczepankiewicz A.   +2 more
europepmc   +1 more source

Therapeutic Antibodies for Mosquito‐Borne Orthoflavivirus Infections: Discovery, Engineering Approaches, and Advances in mRNA‐Based Delivery Systems

Advanced Therapeutics, EarlyView.
This review explores how antibody engineering and display technologies are driving therapeutic advances against mosquito‐borne orthoflaviviruses such as Zika, dengue, and yellow fever viruses. It highlights diverse neutralizing targets on the envelope protein, including the conserved fusion loop, and discusses how Fc engineering, rational antigen ...
Ana Clara Barbosa Antonelli, Lucas Silva Rodrigues, Maria Clara Moura Pinheiro, Sylvia Barbosa Pinhate, Marcelo de Macedo Brígido, Andréa Queiroz Maranhão   +5 more
wiley   +1 more source

Long non-coding RNA <i>MALAT1</i>: A crucial factor in fibrotic diseases. [PDF]

Mol Ther Nucleic Acids
Ran L, Pan W, Feng J, Tang L.
europepmc   +1 more source

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source