Results 71 to 80 of about 39,020 (125)

RNAFlow: RNA Structure & Sequence Design via Inverse Folding-Based Flow Matching [PDF]

arXiv
The growing significance of RNA engineering in diverse biological applications has spurred interest in developing AI methods for structure-based RNA design. While diffusion models have excelled in protein design, adapting them for RNA presents new challenges due to RNA's conformational flexibility and the computational cost of fine-tuning large ...
arxiv  

CoFold: thermodynamic RNA structure prediction with a kinetic twist [PDF]

arXiv, 2012
Existing state-of-the-art methods that take a single RNA sequence and predict the corresponding RNA secondary-structure are thermodynamic methods. These predict the most stable RNA structure, but do not consider the process of structure formation. We have by now ample experimental and theoretical evidence, however, that sequences in vivo fold while ...
arxiv  

Computational identification of non-coding RNAs in Saccharomyces cerevisiae by comparative genomics [PDF]

, 2003
John P. McCutcheon
openalex   +1 more source

Increased serum extrachromosomal circular DNA SORBS1circle level is associated with insulin resistance in patients with newly diagnosed type 2 diabetes mellitus

Cellular & Molecular Biology Letters
Background Extrachromosomal circular DNAs (eccDNAs) exist in human blood and somatic cells, and are essential for oncogene plasticity and drug resistance. However, the presence and impact of eccDNAs in type 2 diabetes mellitus (T2DM) remains inadequately
Xiang Kong, Shu-jun Wan, Tian-bing Chen, Lan Jiang, Yu-jie Xing, Ya-ping Bai, Qiang Hua, Xin-ming Yao, Yong-li Zhao, Hong-mei Zhang, De-guo Wang, Qing Su, Kun Lv   +12 more
doaj   +1 more source

Faster genome annotation of non-coding RNA families without loss of accuracy [PDF]

, 2004
Zasha Weinberg, Walter L. Ruzzo
openalex   +1 more source

Glutathiones’ life in multi-cancers: especially their potential micropetides in liver hepatocellular carcinoma

Discover Oncology
Background Glutathione plays critical roles in detoxifying xenobiotics, cell signaling, cell death and the antioxidant defence in an emerging body of evidence, the most abundant intracellular low molecular weight thiol in tissues.
Didi Ma, Zhenguo Wu, Mengying Zhang, Jian Mao, Wenqin Xu, Lan Jiang, Zuzhen Wang   +6 more
doaj   +1 more source

Co-occurrence of three different plasmids in an extensively drug-resistant hypervirulent Klebsiella pneumoniae isolate causing urinary tract infection

Journal of Global Antimicrobial Resistance, 2020
Objectives: A single carbapenem-resistant, hypervirulent Klebsiella pneumoniae strain has attracted major public concern. The aim of the present study was to better understand the antimicrobial resistance and genetic characteristics of Klebsiella ...
Xiaokui Zhu, Chuanyu Sun, Hongyin Chen, Xiaodie Zhan, Chenxin Liu, Xin Liu, Changwu Yue, Hong Song, Hongling Lu, Xu Jia   +9 more
doaj  

NONCODE: an integrated knowledge database of non-coding RNAs [PDF]

, 2004
Changpeng Liu
openalex   +1 more source

Non-coding RNAs in Ciona intestinalis [PDF]

, 2005
Kristin Missal, Dominic Rose, Peter F. Stadler   +2 more
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Identification of cyanobacterial non-coding RNAs by comparative genome analysis. [PDF]

, 2005
Ilka M. Axmann, Philip Kensche, Jörg Vogel, Stefan Kohl, Hanspeter Herzel, Wolfgang R. Hess   +5 more
openalex   +1 more source