Results 71 to 80 of about 1,318,082 (335)
Frontiers in ImmunologyRecent advancements in genetic engineering have made it possible to modify Natural Killer (NK) cells to enhance their ability to fight against various cancers, including solid tumors.
Chinmayee Priyadarsini Dash +9 more
doaj +1 more source
BMC Genomics, 2017 Background Structured non-coding RNAs play many different roles in the cells, but the annotation of these RNAs is lacking even within the human genome.
Yuki Kato +2 more
doaj +1 more source
Significance of NotchScore and JAG1 in predicting prognosis and immune response of low-grade glioma
Frontiers in Immunology, 2023 IntroductionLow-grade glioma (LGG) is a prevalent malignant tumor in the intracranial region. Despite the advancements in treatment methods for this malignancy over the past decade, significant challenges still persist in the form of drug resistance and ...
Bo Shi +22 more
doaj +1 more source
Into the Wild: GWAS Exploration of Non-coding RNAs [PDF]
, 2018 Genome-wide association studies (GWAS) have proven a fundamental tool to identify common variants associated to complex traits, thus contributing to unveil the genetic components of human disease.
Giral, Hector +2 more
core +1 more source
Non-Coding RNA m6A Modification in Cancer: Mechanisms and Therapeutic Targets
Frontiers in Cell and Developmental Biology, 2021 Recently, N6-methyl-adenosine (m6A) ribonucleic acid (RNA) modification, a critical and common internal RNA modification in higher eukaryotes, has generated considerable research interests.
Da-Hong Chen +3 more
semanticscholar +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Recent advances in the functional explorations of nuclear microRNAs
Frontiers in Immunology, 2023 Approximately 22 nucleotide-long non-coding small RNAs (ncRNAs) play crucial roles in physiological and pathological activities, including microRNAs (miRNAs).
Xiaozhu Hu +11 more
doaj +1 more source
Non-coding RNA as lung disease biomarkers. [PDF]
, 2015 Biomarkers are quantifiable indicators of disease. These surrogates should be specific, sensitive, predictive, robust and easily accessible. A major class of RNA described as non-coding RNA fulfils many of these criteria, and recent studies have ...
Greene, Catherine M +2 more
core +1 more source
A-to-I RNA Editing: Current Knowledge Sources and Computational Approaches with Special Emphasis on Non-Coding RNA Molecules [PDF]
, 2015 RNA editing is a dynamic mechanism for gene regulation attained through the alteration of the sequence of primary RNA transcripts. A-to-I (Adenosine-to-Inosine) RNA editing, which is catalyzed by members of the Adenosine Deaminase Acting on RNA (ADAR ...
Alfredo Ferro +2 more
core +2 more sources
Novel insights into m6A modification of coding and non-coding RNAs in tumor biology: From molecular mechanisms to therapeutic significance [PDF]
, 2022 Jinlin Jia +8 more
openalex +1 more source