Results 81 to 90 of about 970,725 (346)
Non-coding RNA: what is functional and what is junk?
Frontiers in Genetics, 2015 The genomes of large multicellular eukaryotes are mostly comprised of non-protein coding DNA. Although there has been much agreement that a small fraction of these genomes has important biological functions, there has been much debate as to whether the ...
Alexander F. Palazzo, Eliza S. Lee
semanticscholar +1 more source
A guide to naming human non‐coding RNA genes
EMBO Journal, 2020 Research on non‐coding RNA (ncRNA) is a rapidly expanding field. Providing an official gene symbol and name to ncRNA genes brings order to otherwise potential chaos as it allows unambiguous communication about each gene.
Ruth L. Seal +10 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane +16 more
wiley +1 more source
B lymphocytes transdifferentiate into immunosuppressive erythroblast-like cells
Frontiers in Immunology, 2023 Recent studies have demonstrated that a particular group of nucleated cells that exhibit erythroid markers (TER119 in mice and CD235a in humans) possess the ability to suppress the immune system and promote tumor growth.
Zhe Yang +13 more
doaj +1 more source
LncRNADisease: a database for long-non-coding RNA-associated diseases
Nucleic Acids Res., 2012 In this article, we describe a long-non-coding RNA (lncRNA) and disease association database (LncRNADisease), which is publicly accessible at http://cmbi.bjmu.edu.cn/lncrnadisease.
Geng Chen +8 more
semanticscholar +1 more source
Non-Coding RNA m6A Modification in Cancer: Mechanisms and Therapeutic Targets
Frontiers in Cell and Developmental Biology, 2021 Recently, N6-methyl-adenosine (m6A) ribonucleic acid (RNA) modification, a critical and common internal RNA modification in higher eukaryotes, has generated considerable research interests.
Da-Hong Chen +3 more
semanticscholar +1 more source
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
Molecular Oncology, EarlyView.We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi +26 more
wiley +1 more source
Shaping the Genome with Non-Coding RNAs [PDF]
Current Genomics, 2011 The human genome must be tightly packaged in order to fit inside the nucleus of a cell. Genome organization is functional rather than random, which allows for the proper execution of gene expression programs and other biological processes. Recently, three-dimensional chromatin organization has emerged as an important transcriptional control mechanism ...
Josée Dostie +2 more
openaire +4 more sources
tRNA-Derived Small RNA: A Novel Regulatory Small Non-Coding RNA
Genes, 2018 Deep analysis of next-generation sequencing data unveils numerous small non-coding RNAs with distinct functions. Recently, fragments derived from tRNA, named as tRNA-derived small RNA (tsRNA), have attracted broad attention. There are mainly two types of
Siqi Li, Zhengping Xu, J. Sheng
semanticscholar +1 more source
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
Molecular Cancer, 2020 Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients.
A. Bhat +20 more
semanticscholar +1 more source