Potential structural role of non-coding and coding RNAs in the organization of the cytoskeleton at the vegetal cortex of Xenopusoocytes [PDF]
openalex +1 more source
An RNA condensate model for the origin of life [PDF]
The RNA World hypothesis predicts that self-replicating RNAs evolved before DNA genomes and coded proteins. Despite widespread support for the RNA World, self-replicating RNAs have yet to be identified in a natural context, leaving a key 'missing link' for this explanation of the origin of life.
arxiv
EFFICIENT ANNOTATION OF NON-CODING RNA STRUCTURES INCLUDING PSEUDOKNOTS VIA AUTOMATED FILTERS [PDF]
Chunmei Liu+4 more
openalex +1 more source
Nucleotide Sequences of 5' and 3' Non-coding Regions of Pepper Mild Mottle Virus Strain S RNA
M.J. Avila-Rincon+4 more
openalex +1 more source
Automated parallel isolation of multiple species of non-coding RNAs by the reciprocal circulating chromatography method [PDF]
Kenjyo Miyauchi+2 more
openalex +1 more source
Comprehensive benchmarking of large language models for RNA secondary structure prediction [PDF]
Inspired by the success of large language models (LLM) for DNA and proteins, several LLM for RNA have been developed recently. RNA-LLM uses large datasets of RNA sequences to learn, in a self-supervised way, how to represent each RNA base with a semantically rich numerical vector.
arxiv
The human PINK1 locus is regulated in vivo by a non-coding natural antisense RNA during modulation of mitochondrial function [PDF]
Camilla Schéele+8 more
openalex +1 more source
Viral myocarditis (VM) is a clinically common inflammatory disease. Accumulating literature has indicated that M2 macrophages protect mice from Coxsackievirus B3 (CVB3)-induced VM.
Yingying Zhang+8 more
doaj
RiboFlow: Conditional De Novo RNA Sequence-Structure Co-Design via Synergistic Flow Matching [PDF]
Ribonucleic acid (RNA) binds to molecules to achieve specific biological functions. While generative models are advancing biomolecule design, existing methods for designing RNA that target specific ligands face limitations in capturing RNA's conformational flexibility, ensuring structural validity, and overcoming data scarcity.
arxiv