Results 81 to 90 of about 963,524 (371)

RNAcentral: a hub of information for non-coding RNA sequences

Nucleic Acids Res., 2018
RNAcentral is a comprehensive database of non-coding RNA (ncRNA) sequences, collating information on ncRNA sequences of all types from a broad range of organisms.
B. Sweeney, Anton I. Petrov, Boris Burkov, R. Finn, A. Bateman, M. Szymanski, W. Karłowski, J. Gorodkin, S. Seemann, J. Cannone, Robin Gutell, P. Fey, S. Basu, Simon Kay, G. Cochrane, Kostantinos Billis, D. Emmert, Steven J. Marygold, R. Huntley, R. Lovering, A. Frankish, Patricia P. Chan, T. Lowe, E. Bruford, Ruth L. Seal, J. Vandesompele, P. Volders, M. Paraskevopoulou, Lina Ma, Zhang Zhang, S. Griffiths-Jones, J. Bujnicki, Pietro Boccaletto, J. Blake, C. Bult, Runsheng Chen, Yi Zhao, V. Wood, Kim M Rutherford, Elena Rivas, J. Cole, S. Laulederkind, M. Shimoyama, M. Gillespie, M. Orlic-Milacic, Ioanna Kalvari, Eric P. Nawrocki, S. Engel, J. Cherry, Silva Team, T. Berardini, A. Hatzigeorgiou, D. Karagkouni, K. Howe, Paul Davis, M. Dinger, Shunmin He, M. Yoshihama, N. Kenmochi, P. Stadler, K. Williams   +60 more
semanticscholar   +1 more source

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Epigenetic regulation in myocardial infarction: Non-coding RNAs and exosomal non-coding RNAs

Frontiers in Cardiovascular Medicine, 2022
Myocardial infarction (MI) is one of the leading causes of deaths globally. The early diagnosis of MI lowers the rate of subsequent complications and maximizes the benefits of cardiovascular interventions. Many efforts have been made to explore new therapeutic targets for MI, and the therapeutic potential of non-coding RNAs (ncRNAs) is one good example.
Sara Fadaei, Fatemeh Zarepour, Fatemeh Zarepour, Mehrnoosh Parvaresh, Alireza Motamedzadeh, Seyed Saeed Tamehri Zadeh, Amirhossein Sheida, Amirhossein Sheida, Mohammad Shabani, Mohammad Shabani, Michael R. Hamblin, Mehdi Rezaee, Maryam Zarei, Hamed Mirzaei   +13 more
openaire   +3 more sources

The synergistic immunotherapeutic impact of engineered CAR-T cells with PD-1 blockade in lymphomas and solid tumors: a systematic review

Frontiers in Immunology
Currently, therapies such as chimeric antigen receptor-T Cell (CAR-T) and immune checkpoint inhibitors like programmed cell death protein-1 (PD-1) blockers are showing promising results for numerous cancer patients.
Bibhu Prasad Satapathy, Pooja Sheoran, Rohit Yadav, Dewan Chettri, Dhruba Sonowal, Chinmayee Priyadarsini Dash, Prachi Dhaka, Vivek Uttam, Ritu Yadav, Manju Jain, Aklank Jain   +10 more
doaj   +1 more source

Unlocking the potential of tumor‐derived DNA in urine for cancer detection: methodological challenges and opportunities

Molecular Oncology, EarlyView.
Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever, Renske D. M. Steenbergen   +1 more
wiley   +1 more source

Non‐coding RNAs in cardiac hypertrophy [PDF]

The Journal of Physiology, 2017
AbstractHeart failure is one of the largest contributors to disease burden and healthcare outflow in the Western world. Despite significant progress in the treatment of heart failure, disease prognosis remains very poor, with the only curative therapy still being heart transplantation.
Lara Ottaviani, Paula A. da Costa Martins, Paula A. da Costa Martins   +2 more
openaire   +3 more sources

Predicting RNA-small molecule binding sites by 3D structure [PDF]

arXiv, 2023
The prediction of RNA-small molecule binding sites is crucial for the discovery of effective drugs. Various computational methods have been developed to address this challenge, using information about the structure and sequence of RNA. In this study, we introduce CplxCavity, a combination of a new algorithm and a machine learning model specifically ...
arxiv  

Antitumor activity of genetically engineered NK-cells in non-hematological solid tumor: a comprehensive review

Frontiers in Immunology
Recent advancements in genetic engineering have made it possible to modify Natural Killer (NK) cells to enhance their ability to fight against various cancers, including solid tumors.
Chinmayee Priyadarsini Dash, Dhruba Sonowal, Prachi Dhaka, Rohit Yadav, Dewan Chettri, Bibhu Prasad Satapathy, Pooja Sheoran, Vivek Uttam, Manju Jain, Aklank Jain   +9 more
doaj   +1 more source

LncRNADisease: a database for long-non-coding RNA-associated diseases

Nucleic Acids Res., 2012
In this article, we describe a long-non-coding RNA (lncRNA) and disease association database (LncRNADisease), which is publicly accessible at http://cmbi.bjmu.edu.cn/lncrnadisease.
Geng Chen, Ziyun Wang, Dongqing Wang, Chengxiang Qiu, Mingxi Liu, Xing Chen, Qipeng Zhang, Guiying Yan, Qinghua Cui   +8 more
semanticscholar   +1 more source

A guide to naming human non‐coding RNA genes

EMBO Journal, 2020
Research on non‐coding RNA (ncRNA) is a rapidly expanding field. Providing an official gene symbol and name to ncRNA genes brings order to otherwise potential chaos as it allows unambiguous communication about each gene.
Ruth L. Seal, Ling-Ling Chen, S. Griffiths-Jones, T. Lowe, M. Mathews, Dawn O’Reilly, A. Pierce, P. Stadler, I. Ulitsky, S. Wolin, E. Bruford   +10 more
semanticscholar   +1 more source