Results 71 to 80 of about 442,954 (307)

Risk Factors of Non-Communicable Diseases in a Frontier, Outermost, and Least Developed (3T) Archipelagic Region of Indonesia: a Community Study [PDF]

, 2021
Tiara Putri Leksono, Auliana R. P. Hidayat, Fitrawan Silvano, Lutfan Lazuardi   +3 more
openalex   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Exposure to abuse and changes in cardiometabolic risk profiles over 3 years in young South African women

BMC Public Health
Background South African women experience high rates of abuse and cardiometabolic diseases, but research on their relationship is less investigated. This study examined the associations of exposure to abuse in childhood and adulthood with cardiometabolic
Kim Anh Nguyen, Andre Pascal Kengne, Unati Nqebelele, Nasheeta Peer   +3 more
doaj   +1 more source

Vaccines against non-communicable diseases

Current Opinion in Immunology, 2010
Chronic non-communicable diseases (NCDs) are increasingly recognized as the major cause of morbidity and mortality worldwide. Effective, affordable and broadly accessible medicines for their treatment are much sought after. Therapeutic B-cell vaccines aim at inducing neutralizing auto-reactive antibodies against important mediators of such diseases ...
Röhn, T, Bachmann, M
openaire   +2 more sources

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Predicting firefighting operation time in urban areas using machine learning: identifying key determinants for improved emergency response

Discover Applied Sciences
Background Urban fires pose significant risks, resulting in substantial financial and human losses. Effective management of firefighting operations is crucial, where response times play a vital role in minimizing casualties and damages.
Ali Sahebi, Hojjat Sayyadi, Bahram Havasy, Yousef Veisani   +3 more
doaj   +1 more source

Quality of life among the patients with non-communicable diseases [PDF]

, 2020
Sharath Vishwaraj, Sharanabasappa Algoodkar   +1 more
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Effort–reward imbalance and non-communicable diseases as predictors of sleep quality among Iranian employees

Discover Social Science and Health
Introduction Sleep quality is a key health indicator influenced by various psychosocial and physiological factors. This study aimed to investigate the effects of effort–reward imbalance, and non-communicable diseases (NCDs) on sleep quality among ...
Neda Mohammadi, Mitra Salehi, Mehdi Osooli, Edris Kakemam, Zahra Hosseinkhani   +4 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source