Results 31 to 40 of about 729,139 (268)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Dynamic behavior of enzyme kinetics cooperative chemical reactions

AIP Advances
This article uses computational mathematics to investigate the dynamics of cooperative occurrences in chemical reactions inside living organisms. We study the dynamics of complex systems using mathematical models based on ordinary differential equations,
Akhtar Jan, Rehan Ali Shah, Hijaz Ahmad, Hazrat Bilal, Bandar Almohsen   +4 more
doaj   +1 more source

A Regional Perspective of Socio-Ecological Predictors for Fruit and Nut Tree Varietal Diversity Maintained by Farmer Communities in Central Asia

World
The five independent countries of Central Asia, namely Kazakhstan, Kyrgyzstan, Tajikistan, Turkmenistan, and Uzbekistan, contain one of the richest areas in the world for the specific and intraspecific diversity of temperate fruit and nut tree species ...
Muhabbat Turdieva, Agnès Bernis-Fonteneau, Maira Esenalieva, Abdihalil Kayimov, Ashirmuhammed Saparmyradov, Khursandi Safaraliev, Kairkul Shalpykov, Paolo Colangelo, Devra I. Jarvis   +8 more
doaj   +1 more source

A Neural Pattern Generator that Exhibits Arousal-Dependant Human Gait Transitions [PDF]

, 1993
A neural pattern generator based upon a non-linear cooperative-competitive feedback neural network is presented. It can generate the two standard human gaits: the walk and the run.
Cohen, Michael A., Grossberg, Stephen, Pribe, Christopher A.   +2 more
core   +1 more source

Cooperative Carbon Dioxide Adsorption in Alcoholamine- and Alkoxyalkylamine-Functionalized Metal-Organic Frameworks. [PDF]

, 2020
A series of structurally diverse alcoholamine- and alkoxyalkylamine-functionalized variants of the metal-organic framework Mg2 (dobpdc) are shown to adsorb CO2 selectively via cooperative chain-forming mechanisms.
Forse, Alexander C, Kim, Eugene J, Lee, Jung-Hoon, Long, Jeffrey R, Mao, Victor Y, McGuirk, C Michael, Milner, Phillip J, Neaton, Jeffrey B, Porter-Zasada, Leo B, Reimer, Jeffrey A, Siegelman, Rebecca L   +10 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The provision of quality in a bilateral search market [PDF]

We accomplish two goals. First, we provide a non-cooperative foundation for the use of the Nash bargaining solution in search markets. This finding should help to close the rift between the search and the matching-and-bargaining literature.
Clara Ponsat?Author-Email: Clara.ponsati@uab.es, J?sef S?ovics   +1 more
core   +3 more sources

A dynamic confrontational game model of uav’s data link in the complicated electromagnetic environment

Scientific Reports
To select the optimal confrontational strategy for an unmanned aerial vehicle’s (UAV) data link in the complicated electromagnetic environment of the battlefield, based on the non-cooperative game theory, this paper builds a dynamic confrontational game ...
Peiwei Gao, Yongfeng Zhi
doaj   +1 more source

A Game Lane Changing Model Considering Driver’s Risk Level in Ramp Merging Scenario

World Electric Vehicle Journal, 2023
A ramp merging decision as an important part of the lane change model plays a crucial role in the efficiency and safety of the entire merging process. However, due to the inevitability of on-ramp merging, the limitations of the road environment, and the ...
Guo Yang, Shihuan Liu, Ming Ye, Chengcheng Tang, Yi Fan, Yonggang Liu   +5 more
doaj   +1 more source