Results 81 to 90 of about 135,492 (229)

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

open access: yesFEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The dynamics of biomedical research organization in Brazil: the anatomy of a recent experience at the Oswaldo Cruz Foundation - DOI: 10.3395/reciis.v3i2.255en

open access: yesRECIIS, 2009
Biomedical research has undergone changes in the last four decades which have affected the design of new scientific approaches, the study of diseases associated with pathogenic microorganisms and the development of new products and industrial production ...
Márcia de Oliveira Teixeira   +2 more
doaj  

Nauplius Optimization for Autonomous Hydrodynamics

open access: yesIEEE Access
Autonomous underwater vehicle (AUV) swarms offer significant potential for environmental monitoring, subsea exploration, and infrastructure inspection, but effective coordination remains a major challenge in dynamic aquatic environments.
Shyalan Ramesh, Scott Mann, Alex Stumpf
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Large non-cooperative games : foundations and tools [PDF]

open access: yes
Following Schmeidler (1973) and Mas-Colell (1984), economists have typically\ud used aggregative games with a continuum of players to model strategic environments\ud with a large number of participants. In these games a player's payoff\ud depends on her own strategy and on an average of the strategies of everyone in\ud the game.
openaire  

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Role and task allocation framework for wheeled soccer robot collaboration with latent knowledge estimation

open access: yesDiscover Robotics
This paper presents a novel framework for modeling role and task allocation in cooperative wheeled soccer robot systems by leveraging latent knowledge extracted from past collaborative interactions.
Mohammad Salah Uddin
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

A Game Theory-Based Approach Considering Car-Following Behavior for Modeling Merging Behavior at Expressway On-Ramp Sections

open access: yesIEEE Access
Merging at expressway on-ramp sections is a typical mandatory lane-changing maneuver that often causes traffic conflicts and bottlenecks. Although game-theoretic models have been widely applied to describe merging interactions, many existing studies pay ...
Chunyi Wei, Toshiyuki Yamamoto
doaj   +1 more source

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