Results 41 to 50 of about 10,930,855 (302)

The concept of vulnerability and its relation to equality in the context of human rights: cases from climate change, anti-discrimination and asylum

open access: yesFrontiers in Sociology
The article analyzes the concept of vulnerability and its relation to the principles of equality and non-discrimination based on a theoretical discussion and the analysis of the concept in three case studies in different human rights areas.
Monika Mayrhofer   +2 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Events leading to Sexual Orientation addition to University of Utah Non-Discrimination Policy

open access: yes, 2022
Text document Summary of events leading to Sexual Orientation being added to the Non-Discrimination Policy at the University of UtahConverted from .docx to .pdf for ...
Connell O\u27Donovan
core  

Protection of fundamental rights in the context of surrogacy: A review of the recent case law of the European court of human rights [PDF]

open access: yesZbornik Radova Pravnog Fakulteta u Nišu
Surrogate motherhood is one of the most ethically sensitive phenomena today. Different views on the nature, purpose and consequences of surrogate motherhood lead to different approaches regarding political and legal regulation of surrogacy at the state ...
Radovanović Marina
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Multiple discrimination in law [PDF]

open access: yes, 2011
The paper forms part of the project 'GenderRace - The Use of Racial Anti-Discrimination Laws: Gender and Citizenship in a Multicultural Context', funded by the EU Seventh Framework Programme, Grant Agreement - SSH7-CT-2007-217237Acknowledgement: The ...
Howard, Erica   +2 more
core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

THE CHALLENGE OF OVERCOMING INSTITUTIONAL BARRIERS TO END RACIAL DISCRIMINATION IN THE WORKPLACE

open access: yesSur: International Journal on Human Rights, 2018
Colombia is one of the countries with the most anti-discrimination laws in Latin America. In this rare legislative cocktail, there are very specific laws, such as the anti-discrimination law that criminalises discrimination, as well as more general laws,
Maryluz Barragán González
doaj  

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Conclusion

open access: yes, 2022
This book explores non-discrimination in Turkey by dividing the principle into issue areas. It provides a detailed analysis of many areas within the principle of non-discrimination.
Gözde Yılmaz, Yilmaz,G.
core   +1 more source

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