Results 41 to 50 of about 11,450,544 (300)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The concept of vulnerability and its relation to equality in the context of human rights: cases from climate change, anti-discrimination and asylum

Frontiers in Sociology
The article analyzes the concept of vulnerability and its relation to the principles of equality and non-discrimination based on a theoretical discussion and the analysis of the concept in three case studies in different human rights areas.
Monika Mayrhofer, Margit Ammer, Katrin Wladasch   +2 more
doaj   +1 more source

Protection of fundamental rights in the context of surrogacy: A review of the recent case law of the European court of human rights [PDF]

Zbornik Radova Pravnog Fakulteta u Nišu
Surrogate motherhood is one of the most ethically sensitive phenomena today. Different views on the nature, purpose and consequences of surrogate motherhood lead to different approaches regarding political and legal regulation of surrogacy at the state ...
Radovanović Marina
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Events leading to Sexual Orientation addition to University of Utah Non-Discrimination Policy

, 2022
Text document Summary of events leading to Sexual Orientation being added to the Non-Discrimination Policy at the University of UtahConverted from .docx to .pdf for ...
Connell O\u27Donovan
core  

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Multiple discrimination in law [PDF]

, 2011
The paper forms part of the project 'GenderRace - The Use of Racial Anti-Discrimination Laws: Gender and Citizenship in a Multicultural Context', funded by the EU Seventh Framework Programme, Grant Agreement - SSH7-CT-2007-217237Acknowledgement: The ...
Howard, Erica, National Commission for the Promotion of Equality (NCPE), Think Equal, Symposium on Multiple Discrimination   +2 more
core  

THE CHALLENGE OF OVERCOMING INSTITUTIONAL BARRIERS TO END RACIAL DISCRIMINATION IN THE WORKPLACE

Sur: International Journal on Human Rights, 2018
Colombia is one of the countries with the most anti-discrimination laws in Latin America. In this rare legislative cocktail, there are very specific laws, such as the anti-discrimination law that criminalises discrimination, as well as more general laws,
Maryluz Barragán González
doaj  

Queering and diversifying gender in equality work at European higher education institutions

Gender, 2019
Against the background of recent changes to EU legislation to meet the demands and needs of LGBTIQ* communities, the authors seek to situate a queered and diversified understanding of gender firmly at the centre of the gender equality discourse in higher
Lisa Mense, Stephanie Sera, Sarah Vader
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source