Results 221 to 230 of about 10,122,524 (287)

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Oral Microbiota and Clinical Outcomes in Allogenic Hematopoietic Stem Cell Transplantation: A Systematic Review. [PDF]

Microorganisms
da Silva JL, Soares Ferreira Junior A, Alvarez DAN, Souza LDS, Machado LD, Cantrell S, Chao NJA, de Oliveira GLV.   +7 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Observing ideologies. A systems-theoretical approach. [PDF]

Front Sociol
Klement K.
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Awaited paradigm shift in marine N₂ fixing ecology. [PDF]

Natl Sci Rev
Inomura K.
europepmc   +1 more source

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Acute myeloid leukemia and gut microbiome: bidirectional effects and opportunities for intervention. [PDF]

Ann Hematol
Arora K, Chowdhary R, Shenoy A, Kapadia C, Paras F, Vora N, Arora A, Chowdhary R, Arora A, Goyal M, Matt-Amaral L.   +10 more
europepmc   +1 more source

Unraveling the Intestinal Microbiota Conundrum in Allogeneic Hematopoietic Stem Cell Transplantation: Fingerprints, Clinical Implications and Future Directions. [PDF]

J Clin Med
Soares Ferreira Júnior A, Rodrigues da Silva BF, Luiz da Silva J, Trovão da Silva M, Feliciano JVP, Colturato I, Barros GMN, Scheinberg P, Chao NJA, de Oliveira GLV.   +9 more
europepmc   +1 more source

AWhen screams go unheard: covert violence, women victims, and social denial. [PDF]

BMC Womens Health
Saedi Z, Norouzi Aliabad F, Taheri E, Azmoude E.   +3 more
europepmc   +1 more source