Results 51 to 60 of about 11,194,247 (285)
Improved solution to the non-domination level update problem [PDF]
Non-domination level update problem is to sort the non-dominated fronts after insertion or deletion of a solution. Generally the solution to this problem requires to perform the complete non-dominated sorting which is too expensive in terms of number of ...
S. Mishra, S. Mondal, S. Saha
semanticscholar +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Self-determination as non-domination [PDF]
This article conceptualizes self-determination as non-domination, and distinguishes this from the more standard concept of self-determination as noninterference. Principles of non-domination imply relationships between self-determining units and the joint regulation of such relationships.
openaire +4 more sources
Freedom as Non-domination and Democratic Inclusion
According to neo-republicans, democracy is morally justified because it is among the prerequisites for freedom as non-domination. The claim that democracy secures freedom as non-domination needs to explain why democratic procedures contribute to non ...
L. Beckman, J. Rosenberg
semanticscholar +1 more source
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
The equitable non-split domination number of graphs
Finding a group of dominant servers is a necessary step towards optimising service provisioning to all clients in the complex world of server-client networks. This crucial decision rests on the non-split dominance number in the graph architecture.
Samuel Jebisha Esther +2 more
doaj +1 more source
Non-Domination, Workplace Republicanism, and the Justification of Worker Voice and Control
Recent years have seen two distinct responses emerge within republican political theory to the problem of managerial domination in the workplace. The first, as found within the ‘neorepublican’ theories of Philip Pettit and Frank Lovett, argues that, in ...
K. Breen
semanticscholar +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

