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Colloids and Surfaces B: Biointerfaces, 2017
The physical characteristics of viruses needs to be understood in order to manipulate the interaction of viruses with host cells, as well as to create specific molecular recognition techniques to detect, purify, and remove viruses. Viruses are generally believed to be positively charged at physiological pH, but there are few other defining ...
C. Heldt +3 more
semanticscholar +3 more sources
The physical characteristics of viruses needs to be understood in order to manipulate the interaction of viruses with host cells, as well as to create specific molecular recognition techniques to detect, purify, and remove viruses. Viruses are generally believed to be positively charged at physiological pH, but there are few other defining ...
C. Heldt +3 more
semanticscholar +3 more sources
Journal of Molecular Biology, 2016
In the absence of lipid envelopes and associated fusion proteins, non-enveloped viruses employ membrane lytic peptides to breach the limiting membranes of host cells. Although several of these lytic peptides have been identified and characterized, their manner of deployment and interaction with host membranes remains unclear in most cases. We are using
Saumya Bajaj +4 more
semanticscholar +3 more sources
In the absence of lipid envelopes and associated fusion proteins, non-enveloped viruses employ membrane lytic peptides to breach the limiting membranes of host cells. Although several of these lytic peptides have been identified and characterized, their manner of deployment and interaction with host membranes remains unclear in most cases. We are using
Saumya Bajaj +4 more
semanticscholar +3 more sources
Adsorption of a non-enveloped mammalian virus to functionalized nanofibers
Colloids and Surfaces B: Biointerfaces, 2014In the pursuit of finding superior methods to remove pathogens from drinking water, this study examines the adsorption of a non-enveloped, mammalian virus to highly charged nanofibers. N-[(2-Hydroxyl-3-trimethylammonium) propyl] chitosan (HTCC) nanofibers were synthesized by the addition of a quaternary amine to chitosan.
Xue, Mi, Caryn L, Heldt
openaire +2 more sources
Journal of Bioscience and Bioengineering, 2018
UV-C treatment has been shown to be a powerful way to inactivate non-enveloped viruses in water samples. However, little is known about how the viruses were inactivated by UV-C radiation.
Tsuyoshi Tanaka +4 more
semanticscholar +1 more source
UV-C treatment has been shown to be a powerful way to inactivate non-enveloped viruses in water samples. However, little is known about how the viruses were inactivated by UV-C radiation.
Tsuyoshi Tanaka +4 more
semanticscholar +1 more source
Current Protein & Peptide Science, 2008
Host cell entry by influenza and other enveloped viruses is well characterized, however, the manner in which non-enveloped viruses deliver their genome across host cell membranes in the absence of membrane fusion remains unresolved. The discovery of short, membrane altering, amphipathic or hydrophobic sequences in several non-enveloped virus capsid ...
Manidipa Banerjee, John E. Johnson
semanticscholar +3 more sources
Host cell entry by influenza and other enveloped viruses is well characterized, however, the manner in which non-enveloped viruses deliver their genome across host cell membranes in the absence of membrane fusion remains unresolved. The discovery of short, membrane altering, amphipathic or hydrophobic sequences in several non-enveloped virus capsid ...
Manidipa Banerjee, John E. Johnson
semanticscholar +3 more sources
Journal of Photochemistry and Photobiology B: Biology, 1995
The non-enveloped picornaviruses, which are particularly resistant to physicochemical inactivation, include the aetiological agents of poliomyelitis, hepatitis A and E and infectious common cold (rhinovirus). In this work we used human rhinovirus type 5 (RV-5) cultivated in VERO cells to study the photoinactivating effects of several phthalocyanines ...
S. Gaspard +2 more
semanticscholar +3 more sources
The non-enveloped picornaviruses, which are particularly resistant to physicochemical inactivation, include the aetiological agents of poliomyelitis, hepatitis A and E and infectious common cold (rhinovirus). In this work we used human rhinovirus type 5 (RV-5) cultivated in VERO cells to study the photoinactivating effects of several phthalocyanines ...
S. Gaspard +2 more
semanticscholar +3 more sources
Science of the Total Environment
The coagulation process has a high potential as a treatment method that can handle pathogenic viruses including emerging enveloped viruses in drinking water treatment process which can lower infection risk through drinking water consumption.
Siriwara Maneein +4 more
semanticscholar +1 more source
The coagulation process has a high potential as a treatment method that can handle pathogenic viruses including emerging enveloped viruses in drinking water treatment process which can lower infection risk through drinking water consumption.
Siriwara Maneein +4 more
semanticscholar +1 more source
Hepatitis E virus: a non-enveloped member of the 'alpha-like' RNA virus supergroup?
Seminars in Virology, 1993Abstract At least two different forms of fecal-orally transmitted viral hepatitis have been identified and characterized at the molecular level. The first agent characterized was a picornavirus known as the hepatitis A virus (HAV). A second fecal-orally transmitted agent, the hepatitis E virus (HEV), is epidemiologically distinct, due in part to the ...
Michael A. Purdy +4 more
openaire +1 more source
, 2021
Meeting the increasing demand for vaccines throughout the world is key to decrease the spread of infectious diseases. The switch to a fully continuous vaccine manufacturing process would increase productivity and the supply of crucial vaccines. To aid in
Dylan G Turpeinen +8 more
semanticscholar +1 more source
Meeting the increasing demand for vaccines throughout the world is key to decrease the spread of infectious diseases. The switch to a fully continuous vaccine manufacturing process would increase productivity and the supply of crucial vaccines. To aid in
Dylan G Turpeinen +8 more
semanticscholar +1 more source
Purification of a non-enveloped virus using sequential aqueous two-phase extraction
Journal of Chromatography AVirus-based vaccines and therapies require a purification method that is both cost-effective and easily scalable. An aqueous two-phase system (ATPS) consisting of polyethylene glycol (PEG) and citrate salt has been proven to deliver high virus recoveries along with high impurity removal.
Natalie M. Nold +10 more
openaire +3 more sources