Changes of colour and non-enzymatic browning indexes of cloudy apple-berry juices upon storage
Anna Gliszczyńska‐Świgło +1 more
openalex +1 more source
A Natural Sweetener‐inducible Genetic Switch Controls Therapeutic Protein Expression in Mammals
This study develops a natural sweetener, the psicose‐inducible transgene expression (PURE) system based on an Agrobacterium tumefaciens–derived transcriptional repressor PsiR. The PURE system is highly specific to psicose, being insensitive to other sugars and structurally similar molecules.
Longliang Qiao +16 more
wiley +1 more source
Multifunctional kojic acid-tetrahydroisoquinoline hybrids: Synthesis, tyrosinase inhibition, and applications in the anti-browning of fresh-cut mushrooms. [PDF]
Lv M +7 more
europepmc +1 more source
GSK3β‐Regulated Lipolysis is Required for Histone Acetylation and Decidualization in Early Pregnancy
Uterine Gsk3b knockout impairs decidual cell terminal differentiation by causing lipid droplet accumulation. GSK3β phosphorylates RNF213 to promote its lysosomal degradation, thereby enhancing lipolysis. The released fatty acids undergo β‐oxidation to generate acetyl‐CoA, which modulates histone acetylation and regulates decidual cell terminal ...
Peiran Wang +14 more
wiley +1 more source
Integrative transcriptomics and metabolomics analyses reveals Maillard reaction and antioxidant capacity-mediated leaf Browning during the flue-curing process in Nicotiana tabacum L. [PDF]
Xu N +9 more
europepmc +1 more source
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang +12 more
wiley +1 more source
Nondestructive Detection of Polyphenol Oxidase Activity in Various Plum Cultivars Using Machine Learning and Vis/NIR Spectroscopy. [PDF]
Latifi-Amoghin M +4 more
europepmc +1 more source
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu +8 more
wiley +1 more source
Enhancing the Postharvest Stability of Hass Avocado Through Vacuum Impregnation with Antioxidants. [PDF]
Guzmán-Armenteros TM +4 more
europepmc +1 more source

