Results 51 to 60 of about 530,767 (267)
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Highlights Bifunctional atomic catalyst for dual environmental-energetic applications. Unprecedented catalytic performance: simultaneously 99% flowing-phase styrene degradation and 98% FECO at 1000 mA cm−2.
Xiai Zhang +9 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Effective spin physics in two-dimensional cavity QED arrays
We investigate a strongly correlated system of light and matter in two-dimensional cavity arrays. We formulate a multimode Tavis–Cummings (TC) Hamiltonian for two-level atoms coupled to cavity modes and driven by an external laser field which reduces to ...
Jiří Minář +3 more
doaj +1 more source
Quantum gravity states, entanglement graphs and second-quantized tensor networks
In recent years, the import of quantum information techniques in quantum gravity opened new perspectives in the study of the microscopic structure of spacetime.
Eugenia Colafranceschi, Daniele Oriti
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Higher-order and fractional discrete time crystals in clean long-range interacting systems
Discrete time crystals are typically characterized by a period doubled response with respect to an external drive. Here, the authors predict the emergence of rich dynamical phases with higher-order and fractional periods in clean spin-1/2 chains with ...
Andrea Pizzi +2 more
doaj +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Dynamical creation and detection of entangled many-body states in a chiral atom chain
Open quantum systems with chiral interactions can be realized by coupling atoms to guided radiation modes in photonic waveguides or optical fibers. In their steady state these systems can feature intricate many-body phases such as entangled dark states ...
Giuseppe Buonaiuto +3 more
doaj +1 more source
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source

