Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Bioaccumulation of Metals in Some Fish Species from the Romanian Danube River: A Review
The Danube is the second-largest river in Europe and has been subject to pollution in the past. Additionally, in the last few years, the rapid pace of industrialization and urbanization has led to the inevitable pollution of this aquatic ecosystem by ...
Anca Nicoleta Cordeli (Săvescu) +5 more
doaj +1 more source
Metals play a significant role in biological processes, and metal-based drugs nowadays have been commonly used for therapeutic and diagnostic purposes. However, due to severe side effects with metallodrugs and acquired drug resistance, more metallodrugs ...
Wang, H +7 more
core +1 more source
Prospecting the protein design landscape
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Endomembrane Reorganization Induced by Heavy Metals
Plant cells maintain plasmatic concentrations of essential heavy metal ions, such as iron, zinc, and copper, within the optimal functional range. To do so, several molecular mechanisms have to be committed to maintain concentrations of non-essential ...
Monica De Caroli +4 more
doaj +1 more source
The role of Caselio (plant fertilizer) exposure on digestive gland histology and heavy metals accumulation in the freshwater snail, Lanistes carinatus [PDF]
The adverse effects of Caselio, the plant fertilizer (PMR) on the freshwater snail, Lanistes carinatus were studied. Snails were collected from Bahr Shebeen canal, Menoufia Province, Egypt.
Sherin K. Sheir
doaj +1 more source
Essential and Non-Essential Work of Fracture of PI/SiO2 Hybrid Thin Films
Essential work of fracture (EWF) analysis is used to study the effect of the silica doping level on fracture toughness of polyimide/silica (PI/SiO2) hybrid films.
Lu JJ +2 more
core +1 more source
Determination of the Levels of selected essential and non-essential metals in the unprocessed and processed Tomatoes from commercial market of Jimma City [PDF]
Tomato is one of the most important edible nutritional vegetable and accumulates essential and non-essential metals. Tomatoes have, undoubtedly, assumed the status of a food with functional properties, considering the epidemiological evidence of reducing
Ephrem Tilahun +2 more
core

