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Regulation of Insulin Clearance by Non-Esterified Fatty Acids [PDF]

open access: yesBiomedicines, 2022
Insulin stores lipid in adipocytes and prevents lipolysis and the release of non-esterified fatty acids (NEFA). Excessive release of NEFA during sustained energy supply and increase in abdominal adiposity trigger systemic insulin resistance, including in
Sonia M. Najjar   +8 more
doaj   +4 more sources

Non-esterified fatty acids in the ovary: friends or foes? [PDF]

open access: yesReproductive Biology and Endocrinology, 2020
A majority of common metabolic diseases can result in excessive lipolysis, leading to elevated levels of non-esterified fatty acids (NEFAs) in the body fluids.
Vijay Simha Baddela   +2 more
doaj   +2 more sources

Circulating Non-Esterified Fatty Acids as Biomarkers for Fat Content and Composition in Pigs [PDF]

open access: yesAnimals, 2021
Circulating non-esterified fatty acids (NEFA) can reflect the composition of dietary fat or adipose tissues depending on the fasting conditions. Therefore, circulating NEFA may be valuable as biomarkers for meat quality traits, such as intramuscular fat ...
Marc Tor   +8 more
doaj   +2 more sources

Non-esterified fatty acids and telomere length in older adults: The Cardiovascular Health Study [PDF]

open access: yesMetabolism Open, 2020
Background: Telomeres shorten as organisms age, placing limits on cell proliferation and serving as a marker of biological aging. Non-esterified fatty acids (NEFAs) are a key mediator of age-related metabolic abnormalities. We aimed to determine if NEFAs
Peter Ahiawodzi   +5 more
doaj   +2 more sources

The role of microbes in rumen lipolysis and biohydrogenation and their manipulation [PDF]

open access: yesAnimal, 2010
Despite the fact that the ruminant diet is rich in polyunsaturated fatty acids (PUFA), ruminant products – meat, milk and dairy – contain mainly saturated fatty acids (SFA) because of bacterial lipolysis and subsequent biohydrogenation of ingested PUFA ...
M. Lourenço   +2 more
doaj   +3 more sources

The acute effects of dietary carbohydrate reduction on postprandial responses of non-esterified fatty acids and triglycerides: a randomized trial [PDF]

open access: yesLipids in Health and Disease, 2018
Background Postprandial non-esterified fatty acid (NEFA) and triglyceride (TG) responses are increased in subjects with type 2 diabetes mellitus (T2DM) and may impair insulin action and increase risk of cardiovascular disease and death.
Amirsalar Samkani   +9 more
doaj   +2 more sources

Characteristics of the Fatty Acid Composition in Elderly Patients with Occupational Pathology from Organophosphate Exposure [PDF]

open access: yesDiagnostics
Background/Objectives: The delayed effects of organophosphate poisoning may manifest years after exposure, often masked by age-related diseases. The aim of this retrospective cohort study was to identify the biochemical “trace” that could remain in ...
Nikolay V. Goncharov   +9 more
doaj   +2 more sources

Esterified Oxylipins: Do They Matter?

open access: yesMetabolites, 2022
Oxylipins are oxygenated metabolites of fatty acids that share several similar biochemical characteristics and functions to fatty acids including transport and trafficking.
Carmen E. Annevelink   +2 more
doaj   +1 more source

Associations of Early Pregnancy Metabolite Profiles with Gestational Blood Pressure Development

open access: yesMetabolites, 2022
Blood pressure development plays a major role in both the etiology and prediction of gestational hypertensive disorders. Metabolomics might serve as a tool to identify underlying metabolic mechanisms in the etiology of hypertension in pregnancy and lead ...
Sophia M. Blaauwendraad   +5 more
doaj   +1 more source

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