Results 111 to 120 of about 61,302 (299)

Carnitine palmitoyltransferase 1 facilitates fatty acid oxidation in a non-cell-autonomous manner

Cell Reports
Summary: Mitochondrial fatty acid oxidation is facilitated by the combined activities of carnitine palmitoyltransferase 1 (Cpt1) and Cpt2, which generate and utilize acylcarnitines, respectively.
Joseph Choi, Danielle M. Smith, Susanna Scafidi, Ryan C. Riddle, Michael J. Wolfgang   +4 more
doaj   +1 more source

A Hydrogen‐Releasing Nanozyme Engineers a Mitochondrial ROS Amplifier for Self‐Sustaining Catalytic Immunotherapy

Advanced Science, EarlyView.
We developed a RhPd‐H nanozyme that integrates enhanced POD‐mimetic catalytic activity with thermally triggered H2 release. H2 shields and reprograms mitochondria to continuously leak endogenous ·O2−. This dual‐path ROS spatially and temporally disrupts redox homeostasis, inducing persistent oxidative stress for tumor suppression and antitumor immunity,
Mingfan Shi, Jingrui Cao, Tong Wu, Guang Yang, YaWen Yang, Shixin Zhang, Wenwen Su, Hongyu Chu, Yangyang Zhao, Shan Jiang, Qiong Wu, Dongxu Jiao, Fangfang Chen   +12 more
wiley   +1 more source

Oils and fats on food: is it possible to have a healthy diet? [PDF]

, 2017
Oils and fats are an important part of our diet as components of many food formulations. Thus, they are retailed for domestic or hostelry uses and broadly used by food industry for the elaboration of margarines, ice cream, canned food, pre-cooked ...
Garcés Mancheño, Rafael, Martínez-Force, Enrique, Salas, Joaquín J., Venegas Calerón, Mónica   +3 more
core   +2 more sources

Effects of food restriction on serum concentration of glucose, triacylglycerol, beta-hydroxy butyrate, non-esterified fatty acids and urea in pregnant ewes [PDF]

Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2011
Food restriction is a potential unwanted risk for a developing fetus in pregnant ewe. The objective of this study was to study the effects of food restriction on serum concentration of glucose, triacylglycerol, non-esterified fatty acids, beta ...
A Rezapour, M Taghinezhad, GH.R Assadnasab   +2 more
doaj  

Multimodal Multiorgan‐on‐a‐Chip Platform for Probing Liver‐Tumor Interactions and Advancing Prodrug Screening

Advanced Science, EarlyView.
This work introduces a multimodal multi‐OoC platform that overcomes current limitations in liver‐tumor interaction studies and prodrug screening. By integrating dynamic microfluidic circuits, electrochemical sensing, and mass analysis, this platform enables non‐invasive, longitudinal monitoring of drug metabolism and hepatotoxicity, offering a ...
Dan Wang, Yisong Huang, Weijian Zhao, Tian Chen, Siyu Bai, Denghui Guo, Mengying Wang, Yaoyao Zhao, Liang Zhao, Guangsheng Guo, Xiayan Wang   +10 more
wiley   +1 more source

Capsaicin as a Dietary Additive for Dairy Cows: A Meta-Analysis on Performance, Milk Composition, Digestibility, Rumen Fermentation, and Serum Metabolites

Animals
This study aimed to evaluate the effects of dietary supplementation with capsaicin (CAP) on productive performance, milk composition, nutrient digestibility, ruminal fermentation, and serum metabolites of dairy cows using a meta-analytical approach.
José Felipe Orzuna-Orzuna, Juan Eduardo Godina-Rodríguez, Jonathan Raúl Garay-Martínez, Alejandro Lara-Bueno   +3 more
doaj   +1 more source

Injectable Porous Microspheres Loaded With Biomimetic Preconditioned Bone Marrow Mesenchymal Stem Cell‐Derived Exosomes for Vascularized Bone Regeneration

Advanced Science, EarlyView.
Schematic illustration of injectable PDA‐modified GelMA microspheres loaded with BioPre‐Exos for vascularized bone regeneration. ABSTRACT Critical‐sized bone defects remain a highly challenging clinical problem due to insufficient intrinsic self‐healing capacity.
Lijun Li, Hao Zhang, Lingtong Sun, Yingfeng Su, Yang Xu, Jian Huang, Jingchao Wen, Jinjin Zhu, Jianjun Ma, Wenbin Xu   +9 more
wiley   +1 more source

The determinants of fasting and post-load non-esterified fatty acids in older adults: The cardiovascular health study. [PDF]

Metabol Open, 2023
Bene-Alhasan Y, Siscovick DS, Ix JH, Kizer JR, Tracy R, Djoussé L, Mukamal KJ.   +6 more
europepmc   +1 more source

Effect of floor type on the performance, physiological and behavioural responses of finishing beef steers [PDF]

, 2015
peer-reviewedBackground:The study objective was to investigate the effect of bare concrete slats (Control), two types of mats [(Easyfix mats (mat 1) and Irish Custom Extruder mats (mat 2)] fitted on top of concrete slats, and wood-chip to simulate deep ...
A O’Loughlin, AD Fisher, AD Fisher, AWMV Silva De, B Earley, B Earley, B Earley, B Earley, Barry McDonnell, Bernadette Earley, C Bergsten, C Bergsten, C Rouha-Muelleder, D Fraser, D Fraser, D Fraser, D Fraser, D Fraser, D Fraser, D Owens, DE Lowe, DJ Mellor, DM Broom, DM Broom, Edward G. O’Riordan, EFSA, EFSA, EFSA, EM Lynch, G Cozzi, GB Scott, H Irps, H Murata, H Schulze Westerath, I Veissier, J Hannan, J Hultgren, J Rushen, J Vanegas, JA Fregonesi, JH Britt, JNA Tilley, KE Schütz, KE Schütz, KL Graunke, KR Buckham Sporer, L Désiré, M Mazurek, MJ Hotzel, ML Jones, MRP Elmore, OM Radostits, PD Eckersall, PR Greenough, PV Kremer, S Gupta, TM Hill   +56 more
core   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

Advanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang, Tong Dou, Luokai Wang, Jingxian Yang, Wenrui Wang, Shuaitian Guo, Xiangyu Li, Xuefang Huang, Yunlei Xianyu, Dongsheng Wang   +9 more
wiley   +1 more source