Results 61 to 70 of about 793,373 (260)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

CORPORATE GOVERNANCE REFORMS AND FINANCIAL PERFORMANCE: Evidence from Pakistan’s Non-Financial Sector

open access: yesPakistan Journal of Applied Economics
The main purpose of this study is to assess the impact of changes in corporate governance practices, introduced by the Companies Act 2017 (which replaced the Companies Ordinance, 1984), on the financial performance of non-financial sector companies in ...
Imtiaz ARIF, Ehsan MOIN, Jahanzaib ALVI
doaj  

The Moderating Role of Product Market Non-Financial Performance in the Relationship between ESG Activities and Financial Performance in Listed Companies in the Tehran Stock Exchange [PDF]

open access: yesپژوهش‌های تجربی حسابداری
During the past decade, the increase of stakeholders' awareness, in the context of the operational effects of companies on the environment and society, and the key role of management methods in the field of sustainable performance development by ...
Zahra Zoalfaghari   +2 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

MODEL MEDIASI HUBUNGAN ANTARA ENTERPRISE RESOURCES PLANNING SYSTEM, SUPPLY CHAIN MANAGEMENT DAN KINERJA PERUSAHAAN

open access: yesJurnal Riset Akuntansi Terpadu, 2019
The purpose of this study is to provide empirical evidence the mediating effect of supply chain management (SCM) on the relationship between enterprise resources planning (ERP) and firm performance.
Muhammad Nawawi, Taufik Akbar
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

open access: yesFEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin   +12 more
wiley   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Government policy, financial inclusion and performance of SMEs in South Eastern Nigeria

open access: yesInternational Entrepreneurship Review, 2020
Objective: This study seeks to determine the contribution of government policy and Financial Inclusion (FI) to the financial and non-financial performance of SMEs in South Eastern Nigeria.
Kenneth Chukwujioke Agbim
doaj  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

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