Results 41 to 50 of about 221,219 (252)

Association between non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio and sarcopenia based on NHANES

Scientific Reports
The ratio of non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol, or NHHR, has garnered increased attention because of its connection to metabolic diseases.
Ma Yanming, Li Lingjiang, Wang Renji, Yu Xiaojun, Wang yinguang, Li Ruoyu, Hu Huimin, Wang Xiaodong, Hao Dingjun   +8 more
doaj   +1 more source

Elevated non-HDL-C to HDL-C ratio as a marker for NAFLD and liver fibrosis risk: a cross-sectional analysis

Frontiers in Endocrinology
BackgroundDyslipidemia is a known independent risk factor for Nonalcoholic fatty liver disease (NAFLD). However, the relationship between NAFLD and the serum non-high-density lipoprotein cholesterol (non-HDL-C) to high-density lipoprotein cholesterol ...
Yanyan Xuan, Yanyan Xuan, Yanyan Xuan, Minghui Zhu, Linzhi Xu, Shujiao Huangfu, Tongyu Li, Chunbo Liu, Dongdong Zhou   +8 more
doaj   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

Advanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo, Ming Xiao, Mengjun Huang, Dongzi Peng, Ruijiang Zeng, Ruilin Liu, Yuanqiao Zhao, Zhihan Ouyang, Yulong Hong, Zexian Ding, Zhuo Xing, Hao Su, Jinxiang Wang, Wenjun Mao, Xin Jin   +14 more
wiley   +1 more source

Are You Targeting Non–High-Density Lipoprotein Cholesterol?

Journal of the American College of Cardiology, 2009
Non–high-density lipoprotein cholesterol (HDL-C) was defined as the second lipid target of therapy in the 2001 National Cholesterol Education Program-Adult Treatment Panel III guidelines ([1][1]), yet is not yet widely used in clinical practice.
openaire   +1 more source

Pediatric Non–High-Density Lipoprotein Cholesterol, the Metabolic Syndrome, and Insulin Resistance [PDF]

The Journal of Pediatrics, 2011
The article by Li et al in this issue of The Journal presents interesting new data on the cross-sectional association of non-HDL-cholesterol (LDL- and VLDL-cholesterol) with the metabolic syndrome (MetS) in US youth (1) This finding that raises as many issues as it settles, but should guide future analyses into new directions.
Charles J, Glueck, John A, Morrison
openaire   +2 more sources

Utility of non-HDL-C in predicting proteinuria remission of idiopathic membranous nephropathy: a retrospective cohort study

Lipids in Health and Disease, 2021
Background Idiopathic membranous nephropathy (IMN) may have various clinical outcomes. Hyperlipidemia is quite common in IMN. However, the utility of the lipid profile in predicting outcomes remains unknown.
Lei Dong, Wang Wei, Min Han, Gang Xu
doaj   +1 more source

Non-high-density Lipoprotein Cholesterol for Secondary Prevention after Minor Stroke. [PDF]

J Atheroscler Thromb
Wang Y, Jiang Z, Wu S.
europepmc   +3 more sources

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Non-high-density lipoproteins cholesterol and cardiometabolic diseases

Ateroscleroz
   At the present stage, non-high-density lipoprotein cholesterol (non-HDL-C) is intensively studied as a predictor of mortality from cardiovascular diseases. An increase in non-HDL-C content is associated with insulin resistance, which is a pathogenetic factor in the development of atherogenic (mixed) dyslipidemia, which is typical for people with ...
A. P. Kashirina, G. I. Simonova
openaire   +1 more source