Results 41 to 50 of about 801,210 (251)
Architected Lattices with a Topological Transition
Advanced Engineering Materials, EarlyView., 2023 This article develops topological metamaterials showing multidirectional two‐step deformation under compression by embedding contact‐enabled topological mechanisms into lattice structures. Experiments on 3D‐printed 2D and 3D lattices and finite element simulations are conducted to demonstrate the working principle of the topological metamaterials.
Shivam Agarwal, Lihua Jin
wiley +1 more source
Topological aspects of the space of metric measure spaces [PDF]
arXiv, 2023 Gromov introduced two distance functions, the box distance and the observable distance, on the space of isomorphism classes of metric measure spaces and developed the convergence theory of metric measure spaces. We investigate several topological properties on the space equipped with these distance functions toward a deep understanding of convergence ...
arxiv
Advanced Engineering Materials, EarlyView., 2023 A novel method for tracking structural changes in gels using widely accessible microcomputed tomography is presented and validated for various hydro‐, alco‐, and aerogels. The core idea of the method is to track positions of micrometer‐sized tracer particles entrapped in the gel and relate them to the density of the gel network.
Anja Hajnal +3 more
wiley +1 more source
Convergence in the space of compact labeled metric spaces [PDF]
arXiv, 2022 A labeled metric space is intuitively speaking a metric space together with a special set of points to be understood as the geometric boundary of the space. We study basic properties of a recently introduced labeled Gromov-Hausdorff distance, an extension of the classical Gromov-Hausdorff distance, which measures how close two labeled metric spaces are.
arxiv
FEBS Letters, EarlyView.LHCPs are transported to the thylakoid membrane via the (cp)SRP pathway. This process involves a transit complex of (cp)SRP43, (cp)SRP54 and LHCP, which interacts with (cp)FtsY and Alb3 at the membrane. GTP hydrolysis by (cp)SRP54 and (cp)FtsY triggers complex dissociation.
Victor Zegarra +7 more
wiley +1 more source
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
Wasserstein distance and metric trees [PDF]
arXiv, 2021 We study the Wasserstein (or earthmover) metric on the space $P(X)$ of probability measures on a metric space $X$. We show that, if a finite metric space $X$ embeds stochastically with distortion $D$ in a family of finite metric trees, then $P(X)$ embeds bi-Lipschitz into $\ell^1$ with distortion $D$.
arxiv
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
A Unified Framework for Generalizing the Gromov-Hausdorff Metric [PDF]
Probab. Surveys 20: 837-896 (2023), 2018 In this paper, an approach for generalizing the Gromov-Hausdorff metric is presented, which applies to metric spaces equipped with some additional structure. A special case is the Gromov-Hausdorff-Prokhorov metric between measured metric spaces. This abstract framework unifies several existing Gromov-Hausdorff-type metrics for metric spaces equipped ...
arxiv +1 more source
Molecular Oncology, EarlyView.This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini +10 more
wiley +1 more source