Results 71 to 80 of about 194,812 (251)
Factors for Rituximab Refractoriness in AQP4‐IgG+ NMOSD: A Cohort Study
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Neuromyelitis optica spectrum disorder (NMOSD) is a severe autoimmune condition of the central nervous system (CNS), often associated with aquaporin‐4 antibodies (AQP4‐IgG). Rituximab, a CD20+ B‐cell depleting monoclonal antibody, is widely used as first‐line therapy.
Mariano Marrodan +8 more
wiley +1 more source
Fecal Microbiota Transplantation Modulates Th17/Treg Balance via JAK/STAT Pathway in ARDS Rats
Advanced Biology, EarlyView.Fecal microbiota transplantation (FMT) alleviates lung and intestinal injury in lipopolysaccharide (LPS)‐induced acute respiratory distress syndrome (ARDS) in rats. This study demonstrates that FMT restores the balance between Th17 and Treg cells, inhibits the JAK/STAT pathway, and modulates cytokine levels, reducing inflammation and lung damage. These
Dongwei Zhang +8 more
wiley +1 more source
Advanced Biology, EarlyView.The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran +5 more
wiley +1 more source
Advanced Biology, EarlyView.A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso +5 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng +7 more
wiley +1 more source
Hydrogel‐Based Capacitive Sensor Model for Ammonium Monitoring in Aquaculture
Advanced Engineering Materials, EarlyView.Traditional techniques for monitoring aquaculture water quality, particularly ammonium levels, harm fish. This work presents a novel capacitive sensor with an ionic hydrogel transducer to monitor ammonium concentration in real time based on the ammonium‐induced hydrogel dissociation and osmotic pressure. Monitoring aquaculture water quality, especially
Mohammad Mirzaee +3 more
wiley +1 more source
Advanced Engineering Materials, Volume 27, Issue 6, March 2025.ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur +5 more
wiley +1 more source
Advanced Engineering Materials, EarlyView.Temporal power modulation increases weld depth in high‐power laser beam welding of dissimilar round bars by nearly 20% compared to same average continuously welded welding power. The mechanism of action also applies to sheet welding and depends on the inertia of keyhole depth for the modulated laser beam power.
Jan Grajczak +7 more
wiley +1 more source
Simulation of Inhomogeneous Refractive Index Fields Induced by Hot Tailored Forming Components
Advanced Engineering Materials, EarlyView.This article presents a simulation model for simulating inhomogeneous refractive index fields (IRIF) in hot‐forged components, accounting for thermal influences and complex geometries. Through this simulation, a priori knowledge about the propagation of the IRIF can be obtained, allowing for the positioning of the component or an optical measurement ...
Pascal Kern +3 more
wiley +1 more source
Impact of Iron Contamination on Liquid Properties and Microstructural Evolution in AlSi20
Advanced Engineering Materials, EarlyView.Recycled aluminum is much more energy conservative and sustainable than primary aluminum. However, the iron contamination in secondary aluminum is vastly responsible for the degradation of the material properties. Herein, it is aimed to evaluate the influence of iron contamination in hypereutectic Al–Si alloy through thermodynamic as well as ...
Layla Shams Tisha +2 more
wiley +1 more source