Results 11 to 20 of about 237,923 (376)

Face processing limitation to own species in primates: a comparative study in brown capuchins, Tonkean macaques and humans [PDF]

Behav. Processes 73 (07/2006) 107-113, 2006
Most primates live in social groups which survival and stability depend on individuals' abilities to create strong social relationships with other group members. The existence of those groups requires to identify individuals and to assign to each of them
Bahrick, Bentin, Bruce, Campbell, Campbell, Carey, Dasser, de Haan, Diamond, Dufour, Fujita, Fujita, Goren, Gosset, Humphrey, Kay, Kelly, Kendrick, Kendrick, Kendrick, Kendrick, Kim, Kuwahata, Leder, Lutz, Maurer, Meissner, Myowa-Yamakoshi, Nelson, Nelson, Nemanic, Niedenthal, Odile Petit, Olivier Pascalis, Overman, Parr, Parr, Parr, Parr, Pascalis, Pascalis, Pascalis, Pascalis, Pascalis, Pascalis, Perrett, Phelps, Porter, Ridley, Sangrigoli, Simons, Tanaka, Thierry, Tomonaga, Tomonaga, Valentine, Valerie Dufour, van Hoof, Wright, Yin, Zola   +60 more
core   +5 more sources

Characterization of the Fecal Microbiome from Non-Human Wild Primates Reveals Species Specific Microbial Communities [PDF]

PLoS ONE, 2010
BACKGROUND: Host-associated microbes comprise an integral part of animal digestive systems and these interactions have a long evolutionary history. It has been hypothesized that the gastrointestinal microbiome of humans and other non-human primates may ...
A Engelbrektson, B Wood, BA Szekely, Brenda A. Wilson, Bryan A. White, C Dale, C Hickman, Carl J. Yeoman, G Uenishi, GA Botta, GC Baker, HJ Flint, J Lambert, JC Brownlie, JC Frey, JF Rawls, JG Fleagle, JK Nicholson, JL Fish, JL Round, K Holmstrøm, Karen E. Nelson, KE Griswold, KE Jaffe, KR Clarke, KR Clarke, L Dethlefsen, LC Aiello, LV Hooper, M Li, M Schultze, Maksim Sipos, Manolito Torralba, MD Wasserman, MJ McFall-Ngai, N Youssef, NA Moran, NA Moran, PB Eckburg, PD Schloss, PD Schloss, PJ Turnbaugh, PJ Turnbaugh, PJ Turnbaugh, PL Oh, PS Ungar, Q Wang, RE Ley, RE Ley, Rebecca M. Stumpf, Roy Martin Roop II, S Kisidayová, SK Mazmanian, Steven R. Leigh, Suleyman Yildirim, TL Goldberg, Tony L. Goldberg, TZ DeSantis, V Kunin, X Bo   +59 more
core   +12 more sources

Intravenous AAV9 administration results in safe and widespread distribution of transgene in the brain of mini-pig

Frontiers in Cell and Developmental Biology, 2023
Animal models are important for understanding the pathogenesis of human diseases and for developing and testing new drugs. Pigs have been widely used in the research on the cardiovascular, skin barrier, gastrointestinal, and central nervous systems as ...
Yingqi Lin, Caijuan Li, Wei Wang, Jiawei Li, Chunhui Huang, Xiao Zheng, Zhaoming Liu, Xichen Song, Yizhi Chen, Jiale Gao, Jianhao Wu, Jiaxi Wu, Zhuchi Tu, Liangxue Lai, Xiao-Jiang Li, Shihua Li, Sen Yan   +16 more
doaj   +1 more source

Generation of inactivated IL2RG and RAG1 monkeys with severe combined immunodeficiency using base editing

Signal Transduction and Targeted Therapy, 2023
Severe combined immunodeficiency (SCID) encompasses a range of inherited disorders that lead to a profound deterioration of the immune system. Among the pivotal genes associated with SCID, RAG1 and IL2RG play crucial roles.
Xiao Zheng, Chunhui Huang, Yingqi Lin, Bofeng Han, Yizhi Chen, Caijuan Li, Jiawei Li, Yongyan Ding, Xichen Song, Wei Wang, Weien Liang, Jianhao Wu, Jiaxi Wu, Jiale Gao, Chengxi Wei, Xudong Zhang, Zhuchi Tu, Sen Yan   +17 more
doaj   +1 more source

Dynamic Regulation of DNA Methylation and Brain Functions

Biology, 2023
DNA cytosine methylation is a principal epigenetic mechanism underlying transcription during development and aging. Growing evidence suggests that DNA methylation plays a critical role in brain function, including neurogenesis, neuronal differentiation ...
Jiaxiang Xie, Leijie Xie, Huixian Wei, Xiao-Jiang Li, Li Lin   +4 more
doaj   +1 more source

Insights into White Matter Defect in Huntington’s Disease

Cells, 2022
Huntington’s disease (HD) is an autosomal-dominant inherited progressive neurodegenerative disorder. It is caused by a CAG repeat expansion in the Huntingtin gene that is translated to an expanded polyglutamine (PolyQ) repeat in huntingtin protein. HD is
Yize Sun, Huichun Tong, Tianqi Yang, Li Liu, Xiao-Jiang Li, Shihua Li   +5 more
doaj   +1 more source

A new non-human primate model of desiccating stress-induced dry eye disease

Scientific Reports, 2022
Dry eye disease (DED), a multifactorial ocular surface disease, is estimated to affect up to 34% of individuals over 50 years old. Although numerous animal models, including rodents and rabbits, have been developed to mimic the pathophysiologic ...
Li Gong, Yilin Guan, WonKyung Cho, Baowen Li, Lingzhen Pan, Zhenyan Yang, Mingling Wu, Zunyuan Yang, Sunil K. Chauhan, Wen Zeng   +9 more
doaj   +1 more source

Genetically modified large animal models for investigating neurodegenerative diseases

Cell & Bioscience, 2021
Neurodegenerative diseases represent a large group of neurological disorders including Alzheimer’s disease, amyotrophic lateral sclerosis, Parkinson’s disease, and Huntington’s disease.
Weili Yang, Xiusheng Chen, Shihua Li, Xiao-Jiang Li   +3 more
doaj   +1 more source

A Specific Mini‐Intrabody Mediates Lysosome Degradation of Mutant Huntingtin

Advanced Science, 2023
Accumulation of misfolded proteins leads to many neurodegenerative diseases that can be treated by lowering or removing mutant proteins. Huntington's disease (HD) is characterized by the intracellular accumulation of mutant huntingtin (mHTT) that can be ...
Caijuan Li, Yingqi Lin, Yizhi Chen, Xichen Song, Xiao Zheng, Jiawei Li, Jun He, Xiusheng Chen, Chunhui Huang, Wei Wang, Jianhao Wu, Jiaxi Wu, Jiale Gao, Zhuchi Tu, Xiao‐Jiang Li, Sen Yan, Shihua Li   +16 more
doaj   +1 more source

Pathological insights from amyotrophic lateral sclerosis animal models: comparisons, limitations, and challenges

Translational Neurodegeneration, 2023
In order to dissect amyotrophic lateral sclerosis (ALS), a multigenic, multifactorial, and progressive neurodegenerative disease with heterogeneous clinical presentations, researchers have generated numerous animal models to mimic the genetic defects ...
Longhong Zhu, Shihua Li, Xiao-Jiang Li, Peng Yin   +3 more
doaj   +1 more source