Results 201 to 210 of about 120,353 (299)

Nanostructured drug delivery systems for posterior segment eye diseases: Strategies to defy ocular barriers

open access: yesBMEMat, EarlyView.
Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen   +7 more
wiley   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

open access: yesBMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi   +11 more
wiley   +1 more source

Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy

open access: yesBMEMat, EarlyView.
This review systematically summarizes cutting‐edge advances in glycolysis‐rewiring nanomedicines, emphasizing their mechanisms in reversing immunosuppression and reinvigorating antitumor immune responses. Challenges in clinical translation and future directions for designing multifunctional metabolic‐immune modulators are also critically discussed ...
Zilin Ma   +9 more
wiley   +1 more source

IL-6 Blockade Promotes Tolerance of Heart but Not Lung Allografts in Non-Human Primate Simultaneous Organ and Bone Marrow Transplantation Protocols [PDF]

open access: bronze
S.M. Landino   +9 more
openalex   +1 more source

The flexible, the stereotyped and the in‐between: putting together the combinatory tool use origins hypothesis

open access: yesBiological Reviews, EarlyView.
ABSTRACT Tool use research has long made the distinction between tool using that is considered learned and flexible, and that which appears to be instinctive and stereotyped. However, animals with an inherited tool use specialisation can exhibit flexibility, while tool use that is spontaneously innovated can be limited in its expression and facilitated
Jennifer A. D. Colbourne   +1 more
wiley   +1 more source

Beyond mammals: the evolution of chewing and other forms of oropharyngeal food processing in vertebrates

open access: yesBiological Reviews, EarlyView.
ABSTRACT Oropharyngeal food processing exhibits a remarkable diversity among vertebrates, reflecting the evolution of specialised ‘processing centres’ associated with the mandibular, hyoid, and branchial arches. Although studies have detailed various food‐processing strategies and mechanisms across vertebrates, a coherent and comprehensive terminology ...
Daniel Schwarz   +6 more
wiley   +1 more source

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