Results 51 to 60 of about 237,923 (376)

Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. [PDF]

open access: yes, 2018
Non-human primates (NHPs) can serve as a human-like model to study cell therapy using induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs). However, whether the efficacy of NHP and human iPSC-CMs is mechanistically similar remains unknown.
Aguirre, Aitor   +19 more
core   +3 more sources

Antimicrobial resistance and mechanisms of epigenetic regulation

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
The rampant use of antibiotics in animal husbandry, farming and clinical disease treatment has led to a significant issue with pathogen resistance worldwide over the past decades. The classical mechanisms of resistance typically investigate antimicrobial
Xinrui Wang   +5 more
doaj   +1 more source

Topographic Deep Artificial Neural Networks (TDANNs) predict face selectivity topography in primate inferior temporal (IT) cortex [PDF]

open access: yes, 2019
Deep convolutional neural networks are biologically driven models that resemble the hierarchical structure of primate visual cortex and are the current best predictors of the neural responses measured along the ventral stream. However, the networks lack topographic properties that are present in the visual cortex, such as orientation maps in primary ...
arxiv   +1 more source

Cross-species referential signalling events in domestic dogs (Canis familiaris) [PDF]

open access: yes, 2018
Referential gestures are used by a signaller to draw a recipient’s attention to a specific object, individual or event in the environment. These gestures have received much research attention in relation to human and non-human primates with great apes ...
O'Hara, SJ, Worsley, HK
core   +2 more sources

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

open access: yesAdvanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García   +23 more
wiley   +1 more source

Topographic organization of the human and non-human primate subthalamic nucleus [PDF]

open access: yes, 2015
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is used to relieve motor symptoms of Parkinson’s disease. A tripartite system of STN subdivisions serving motoric, associative, and limbic functions was proposed, mainly based on tracing ...
Alfons Schnitzler   +2 more
core   +1 more source

Integration of Perovskite/Low‐Dimensional Material Heterostructures for Optoelectronics and Artificial Visual Systems

open access: yesAdvanced Functional Materials, EarlyView.
Heterojunctions combining halide perovskites with low‐dimensional materials enhance optoelectronic devices by enabling precise charge control and improving efficiency, stability, and speed. These synergies advance flexible electronics, wearable sensors, and neuromorphic computing, mimicking biological vision for real‐time image analysis and intelligent
Yu‐Jin Du   +11 more
wiley   +1 more source

Comparing HD knockin pigs and mice reveals the pathological role of IL-17

open access: yesCell Reports, 2023
Summary: Our previous work has established a knockin (KI) pig model of Huntington’s disease (HD) that can replicate the typical pathological features of HD, including selective striatal neuronal loss, reactive gliosis, and axonal degeneration.
Qingqing Jia   +13 more
doaj  

Occurrence of Ten Protozoan Enteric Pathogens in Three Non-Human Primate Populations

open access: yesPathogens, 2021
Non-human primate populations act as potential reservoirs for human pathogens, including viruses, bacteria and parasites, which can lead to zoonotic infections. Furthermore, intestinal microorganisms may be pathogenic organisms to both non-human primates
Estelle Menu   +9 more
doaj   +1 more source

Bayesian support for Evolution: detecting phylogenetic signal in a subset of the primate family [PDF]

open access: yes, 2017
The theory of evolution states that the diversity of species can be explained by descent with modification. Therefore, all living beings are related through a common ancestor. This evolutionary process must have left traces in our molecular composition.
arxiv   +1 more source

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