Comparison of Non-human Primate versus Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Treatment of Myocardial Infarction. [PDF]
Non-human primates (NHPs) can serve as a human-like model to study cell therapy using induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs). However, whether the efficacy of NHP and human iPSC-CMs is mechanistically similar remains unknown.
Aguirre, Aitor+19 more
core +3 more sources
Antimicrobial resistance and mechanisms of epigenetic regulation
The rampant use of antibiotics in animal husbandry, farming and clinical disease treatment has led to a significant issue with pathogen resistance worldwide over the past decades. The classical mechanisms of resistance typically investigate antimicrobial
Xinrui Wang+5 more
doaj +1 more source
Topographic Deep Artificial Neural Networks (TDANNs) predict face selectivity topography in primate inferior temporal (IT) cortex [PDF]
Deep convolutional neural networks are biologically driven models that resemble the hierarchical structure of primate visual cortex and are the current best predictors of the neural responses measured along the ventral stream. However, the networks lack topographic properties that are present in the visual cortex, such as orientation maps in primary ...
arxiv +1 more source
Cross-species referential signalling events in domestic dogs (Canis familiaris) [PDF]
Referential gestures are used by a signaller to draw a recipient’s attention to a specific object, individual or event in the environment. These gestures have received much research attention in relation to human and non-human primates with great apes ...
O'Hara, SJ, Worsley, HK
core +2 more sources
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García+23 more
wiley +1 more source
Topographic organization of the human and non-human primate subthalamic nucleus [PDF]
Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is used to relieve motor symptoms of Parkinson’s disease. A tripartite system of STN subdivisions serving motoric, associative, and limbic functions was proposed, mainly based on tracing ...
Alfons Schnitzler+2 more
core +1 more source
Heterojunctions combining halide perovskites with low‐dimensional materials enhance optoelectronic devices by enabling precise charge control and improving efficiency, stability, and speed. These synergies advance flexible electronics, wearable sensors, and neuromorphic computing, mimicking biological vision for real‐time image analysis and intelligent
Yu‐Jin Du+11 more
wiley +1 more source
Comparing HD knockin pigs and mice reveals the pathological role of IL-17
Summary: Our previous work has established a knockin (KI) pig model of Huntington’s disease (HD) that can replicate the typical pathological features of HD, including selective striatal neuronal loss, reactive gliosis, and axonal degeneration.
Qingqing Jia+13 more
doaj
Occurrence of Ten Protozoan Enteric Pathogens in Three Non-Human Primate Populations
Non-human primate populations act as potential reservoirs for human pathogens, including viruses, bacteria and parasites, which can lead to zoonotic infections. Furthermore, intestinal microorganisms may be pathogenic organisms to both non-human primates
Estelle Menu+9 more
doaj +1 more source
Bayesian support for Evolution: detecting phylogenetic signal in a subset of the primate family [PDF]
The theory of evolution states that the diversity of species can be explained by descent with modification. Therefore, all living beings are related through a common ancestor. This evolutionary process must have left traces in our molecular composition.
arxiv +1 more source