Results 81 to 90 of about 237,923 (376)

Primates in peril: the significance of Brazil, Madagascar, Indonesia and the Democratic Republic of the Congo for global primate conservation [PDF]

, 2018
Primates occur in 90 countries, but four—Brazil, Madagascar, Indonesia, and the Democratic Republic of the Congo (DRC)—harbor 65% of the world’s primate species (439) and 60% of these primates are Vulnerable, Endangered, or Critically Endangered (IUCN ...
Bicca-Marques, J, Boonratana, R, Cheyne, SM, Dobrovolski, R, Estrada, A, Fuentes, A, Garber, P, Gouveia, S, Jerusalinsky, L, Johnson, S, Kierulf, MCM, Maisels, F, Mittermeier, R, Nekaris, KAI, Nijman, V, Oliveira, L, Raharivololona, B, Ratsimbazafy, J, Rodrigues de Melo, F, Roos, C, Rylands, AB, Schwitzer, C, Setiawan, A, Supriatna, J, Talebi, M, Wedana, M, Wich, SA, Williamson, EA   +27 more
core   +2 more sources

Enhanced Epithelial Cell Uptake of Glycol Chitosan‐Coated PLGA Nanoparticles for Oral Drug Delivery

Advanced Therapeutics, EarlyView.
Here, glycol chitosan (GC)‐coated PLGA NPs are developed to enhance oral drug delivery by enabling dual‐pathway endocytosis via clathrin‐ and caveolae‐mediated mechanisms. Alginate layering coating on GC‐PLGA further improves oral insulin delivery, achieving sustained glucose reduction in diabetic mice.
Huiwen Pang, Wenxuan Yu, Youzhi Wu, Xuqiang Nie, Guojun Huang, Zhi Ping Xu, Chen Chen, Felicity Y. Han   +7 more
wiley   +1 more source

Nonhuman Primate IFITM Proteins Are Potent Inhibitors of HIV and SIV. [PDF]

PLoS ONE, 2016
Interferon-induced transmembrane (IFITM) proteins are potent antiviral factors shown to restrict the infection of many enveloped viruses, including HIV. Here we report cloning and characterization of a panel of nonhuman primate IFITMs.
Jordan Wilkins, Yi-Min Zheng, Jingyou Yu, Chen Liang, Shan-Lu Liu   +4 more
doaj   +1 more source

Face Recognition: Primates in the Wild [PDF]

arXiv, 2018
We present a new method of primate face recognition, and evaluate this method on several endangered primates, including golden monkeys, lemurs, and chimpanzees. The three datasets contain a total of 11,637 images of 280 individual primates from 14 species. Primate face recognition performance is evaluated using two existing state-of-the-art open-source
arxiv  

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Human and Non-Human Primate Intestinal FcRn Expression and Immunoglobulin G Transcytosis [PDF]

, 2013
PURPOSE: To evaluate transcytosis of immunoglobulin G (IgG) by the neonatal Fc receptor (FcRn) in adult primate intestine to determine whether this is a means for oral delivery of monoclonal antibodies (mAbs).
Amanda L. Kauffman, Benjamin Harman, Connie Kliwinski, Edwin Ragwan, Gordon D. Powers, Haimanti Dorai, Jill Giles-Komar, John R. Mabus, Pamela J. Hornby, Philip R. Cooper, Susan H. Tam, Suzanne Thompson, Zhengyin Yan   +12 more
core   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

Advanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu, Guisheng Chen, Rui Hu, Peiwen Liu, Jintao Lou, Wenji Zhao, Zuhong He, Suhua Sha, Yiqing Zheng   +8 more
wiley   +1 more source

Time is TikToking: User perceptions of primate videos on one of the fastest growing social media platforms [PDF]

, 2022
Introduction: With billions of social media users, platforms have a powerful influence on user perceptions of and behaviour toward wild animals. TikTok is known for its large and young user base
CARSTENS, MILENA
core  

Increased expression of mesencephalic astrocyte-derived neurotrophic factor (MANF) contributes to synapse loss in Alzheimer’s disease

Molecular Neurodegeneration
Background The activation of endoplasmic reticulum (ER) stress is an early pathological hallmark of Alzheimer’s disease (AD) brain, but how ER stress contributes to the onset and development of AD remains poorly characterized.
Yiran Zhang, Xiusheng Chen, Laiqiang Chen, Mingting Shao, Wenzhen Zhu, Tingting Xing, Tingting Guo, Qingqing Jia, Huiming Yang, Peng Yin, Xiao-Xin Yan, Jiandong Yu, Shihua Li, Xiao-Jiang Li, Su Yang   +14 more
doaj   +1 more source

Introducing a Central African Primate Vocalisation Dataset for Automated Species Classification [PDF]

arXiv, 2021
Automated classification of animal vocalisations is a potentially powerful wildlife monitoring tool. Training robust classifiers requires sizable annotated datasets, which are not easily recorded in the wild. To circumvent this problem, we recorded four primate species under semi-natural conditions in a wildlife sanctuary in Cameroon with the objective
arxiv