Results 1 to 10 of about 317,078 (143)

Optimization of Milk Substitutes for the Artificial Rearing of Chinese Tree Shrews (Tupaia belangeri chinensis)

open access: yesAnimals, 2022
The Chinese tree shrew (Tupaia belangeri chinensis) has the potential to replace the use of non-human primates in biomedical research. To increase the availability of this species, we have undertaken the ambitious task of establishing inbred lines of the
Jia-Qi Chen   +7 more
doaj   +1 more source

Antioxidant Activity and Anti-Apoptotic Effect of the Small Molecule Procyanidin B1 in Early Mouse Embryonic Development Produced by Somatic Cell Nuclear Transfer

open access: yesMolecules, 2021
As an antioxidant, procyanidin B1(PB1) can improve the development of somatic cell nuclear transfer (SCNT) embryos; PB1 reduces the level of oxidative stress (OS) during the in vitro development of SCNT embryos by decreasing the level of reactive oxygen ...
Wei Gao   +6 more
doaj   +1 more source

Specific inhibition of the NLRP3 inflammasome suppresses immune overactivation and alleviates COVID-19 like pathology in mice

open access: yesEBioMedicine, 2022
Summary: Background: The Coronavirus Disease 2019 (COVID-19) pandemic has been a great threat to global public health since 2020. Although the advance on vaccine development has been largely achieved, a strategy to alleviate immune overactivation in ...
Jianxiong Zeng   +11 more
doaj   +1 more source

Bioactive Peptides and Proteins from Centipede Venoms

open access: yesMolecules, 2022
Venoms are a complex cocktail of biologically active molecules, including peptides, proteins, polyamide, and enzymes widely produced by venomous organisms.
Yalan Han   +3 more
doaj   +1 more source

Extrapolating from Laboratory Behavioral Research on Nonhuman Primates Is Unjustified [PDF]

open access: yes, 2020
Conducting research on animals is supposed to be valuable because it provides information on how human mechanisms work. But for the use of animal models to be ethically justified, it must be epistemically justified.
Crutchfield, Parker
core   +1 more source

Of apples and oranges? The evolution of “monogamy” in non-human primates [PDF]

open access: yes, 2020
Behavioral ecologists, evolutionary biologists, and anthropologists have been long fascinated by the existence of “monogamy” in the animal kingdom.
Di Fore, Anthony   +2 more
core   +2 more sources

Anticarin β Inhibits Human Glioma Progression by Suppressing Cancer Stemness via STAT3

open access: yesFrontiers in Oncology, 2021
Glioma is the most common form of malignant brain cancer. It is very difficult to cure malignant glioma because of the presence of glioma stem cells, which are a barrier to cure, have high tumorigenesis, associated with drug resistance, and responsible ...
Min Zhang   +5 more
doaj   +1 more source

Bioactive Peptides and Proteins from Wasp Venoms

open access: yesBiomolecules, 2022
Wasps, members of the order Hymenoptera, use their venom for predation and defense. Accordingly, their venoms contain various constituents acting on the circulatory, immune and nervous systems.
Lei Luo, Peter Muiruri Kamau, Ren Lai
doaj   +1 more source

Construction and investigation of a circRNA-associated ceRNA regulatory network in Tetralogy of Fallot

open access: yesBMC Cardiovascular Disorders, 2021
Background As the most frequent type of cyanotic congenital heart disease (CHD), tetralogy of Fallot (TOF) has a relatively poor prognosis without corrective surgery.
Haifei Yu, Xinrui Wang, Hua Cao
doaj   +1 more source

Comparative metabolomics in primates reveals the effects of diet and gene regulatory variation on metabolic divergence. [PDF]

open access: yes, 2014
Human diets differ from those of non-human primates. Among few obvious differences, humans consume more meat than most non-human primates and regularly cook their food.
Blekhman, Ran   +5 more
core   +2 more sources

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