Results 41 to 50 of about 188,969 (307)

Linguistic capacity of non-human animals

, 2015
This paper was funded by European Union's Seventh Framework Programme for research, technological development and demonstration. Grant Number: 283871Linguists interested in language evolution tend to focus on combinatorial features and rightly point out ...
Zuberbühler, Klaus, Klaus Zuberbühler, Zuberbuehler, Klaus   +2 more
core   +1 more source

Non-human primate pluripotent stem cells for the preclinical testing of regenerative therapies

Neural Regeneration Research, 2022
Non-human primates play a key role in the preclinical validation of pluripotent stem cell-based cell replacement therapies. Pluripotent stem cells used as advanced therapy medical products boost the possibility to regenerate tissues and organs affected ...
Ignacio Rodriguez-Polo, Rüdiger Behr
doaj   +1 more source

Abstract knowledge in the broken-string problem : evidence from nonhuman primates and pre-schoolers [PDF]

, 2014
There was funding from the Royal Commission for the Exhibition of 1851.There is still large controversy about whether abstract knowledge of physical problems is uniquely human.
Josep Call, Josep Call (109947), Elisabetta Visalberghi (209841), Albiach Serrano, A., Seed, A. ; https://orcid.org/, Visalberghi, E., Sabbatini, Gloria, Visalberghi, Elisabetta, Seed, Amanda Madeleine, Anna Albiach-Serrano (637673), Seed, A., Mayer, C., Amanda Seed, Albiach-Serrano, Anna, Amanda Seed (637675), Call, Josep, Call, J., Gloria Sabbatini, Albiach-Serrano, A. ; https://orcid.org/, Gloria Sabbatini (637674), Carolina Mayer (5660809), Elisabetta Visalberghi, Sabbatini, G., Carolina Mayer, Call, J. ; https://orcid.org/, Anna Albiach-Serrano, Mayer, Carolina Patricia   +26 more
core   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Molecular identification of hemoplasmas in free ranging non–human primates in Thailand

Asian Pacific Journal of Tropical Medicine, 2019
Objective: To survey hemoplasmas infection in free ranging non-human primates from 8 provinces in Thailand. Methods: DNA from ethylenediaminetetraacetic acid blood of 262 free ranging non-human primates were identified as hemoplasmas using PCR and ...
Parut Suksai, Supakarn Kaewchot, Piya Sereerak, Sirinan Boonnan, Bongkotchamat Phimsin, Taksina Jaruwattananon, Kacharin Raschasin, Mutchamon Kaewparuehaschai, Sorraya Siriphet, Benjaporn Bhusri   +9 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Forward and reverse genomic screens enhance the understanding of phenotypic variation in a large Chinese rhesus macaque cohort

Nature Communications
Combining genotype and phenotype data promises to greatly increase the value of macaque as biomedical models for human disease. Here we launch the Macaque Biobank project by deeply sequencing 919 captive Chinese rhesus macaques (CRM) while assessing 52 ...
Bao-Lin Zhang, Yongxuan Chen, Yali Zhang, Yicheng Qiao, Yang Wu, Yi Zhang, Yizheng Lu, Xinran You, Yanling Li, Hong-Di Huang, Qiong Wang, Yijiang Li, Yun Wang, Wenxian Xiao, Hexian Duan, Ming-Hao Qiu, Nan-Hui Chen, Xiaomei Yu, Min-Min Yang, Longbao Lv, David N. Cooper, Ping Zheng, Yong-Gang Yao, Ning Liu, Jian-Hong Wang, Dong-Dong Wu   +25 more
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Quality management for the international transportation of non-human primates [PDF]

Veterinaria Italiana, 2008
Safe and humane transportation of live animals requires dedicated, informed personnel who carefully plan and attend to the details of appropriate animal care and handling throughout the shipping process. Specifically, although transportation of non-human
David B. Elmore
doaj  

The role of mosquitoes in malaria parasite transmission from non-human primates to humans.

Frontiers in Physiology, 2012
Malaria is caused by Plasmodium parasites which are transmitted by anopheline mosquitoes. Until recently, human malaria was considered to be caused by human-specific Plasmodia spp.
Niels O. Verhulst, Renate C. Smallegange, Renate C. Smallegange, Willem eTakken   +3 more
doaj   +1 more source