Results 61 to 70 of about 188,969 (307)

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Investigation of depression-like phenotypes and their behavioral correlates in cynomolgus monkeys (Macaca fascicularis)

BMC Zoology
Background The global burden of depression is heavy, with unclear pathogenesis, relying on animal models for researching neural mechanisms and treatments.
Wei Li, Li Huang, Shi-Gang Liu, Jun Tang
doaj   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Dilated cardiomyopathy in spider monkey (Ateles chamek, Humboldt, 1812)

Brazilian Journal of Veterinary Medicine, 2019
Non-human primates are routinely studied and managed in zoos, conservation breeding centers, and research centers, but there is currently limited information regarding diseases that can affect these animals.
Mário dos Santos Filho, Heloisa Helena de Campos Coutinho Chaves, Bárbara Souza Neil Magalhães, Andressa Kagohara, Fernando Troccoli, Alessandro Galhões, Daniel de Almeida Balthazar, Jonimar Pereira Paiva   +7 more
doaj   +1 more source

Mapping meningeal vasculature in non-human primates

Veins and Lymphatics, 2022
Background. The blood-brain barrier has been the focus of most prior work examining intracranial vasculature in the context of various brain diseases.1 Recently, meningeal vasculature has become more widely recognized as a key contributor to brain ...
Christopher Janson, Kyle Hauser, Scott Muller, Jeffrey H. Kordower, Liudmila Romanova   +4 more
doaj   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

Aspects éthiques et cadres juridiques de la recherche en neurosciences comportementales chez les primates non-humains

Revue de Primatologie
Neuroscience research involving animal models is at the heart of major scientific questions. It provides considerable fundamental knowledge about biological mechanisms at the molecular, cellular and integrated levels, and enables the development of ...
Valentine Morel-Latour, Sabrina Ravel, Manon Dirheimer, Jérôme Sallet   +3 more
doaj   +1 more source

Competence of non-human primates to transmit Leishmania infantum to the invertebrate vector Lutzomyia longipalpis.

PLoS Neglected Tropical Diseases, 2019
Leishmaniasis is a zoonotic disease of worldwide relevance. Visceral leishmaniasis is endemic in Brazil, where it is caused by Leishmania infantum with Lutzomyia longipalpis being the most important invertebrate vector. Non-human primates are susceptible
Ayisa Rodrigues de Oliveira, Guilherme Rafael Gomide Pinheiro, Herlandes P Tinoco, Maria Elvira Loyola, Carlyle Mendes Coelho, Edelberto Santos Dias, Érika Michalsky Monteiro, Fabiana de Oliveira Lara E Silva, Angela Tinoco Pessanha, Andreza Geisiane Maia Souza, Nathália Cristina Lima Pereira, Nelder F Gontijo, Ricardo T Fujiwara, Tatiane Alves da Paixão, Renato Lima Santos   +14 more
doaj   +1 more source

Theories about evolutionary origins of human hepatitis B virus in primates and humans

Brazilian Journal of Infectious Diseases, 2014
Introduction: The human hepatitis B virus causes acute and chronic hepatitis and is considered one of the most serious human health issues by the World Health Organization, causing thousands of deaths per year.
Breno Frederico de Carvalho Dominguez Souza, Jan Felix Drexler, Renato Santos de Lima, Mila de Oliveira Hughes Veiga do Rosário, Eduardo Martins Netto   +4 more
doaj   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source