Results 61 to 70 of about 16,594,316 (254)

Distribution of TT virus (TTV), TTV-like minivirus, and related viruses in humans and nonhuman primates [PDF]

, 2003
TT virus (TTV) and TTV-like minivirus (TLMV) are small DNA viruses with single-stranded, closed circular, antisense genomes infecting man. Despite their extreme sequence heterogeneity (>50%), a highly conserved region in the untranslated region (UTR ...
Thom, K, Lewis, J.C.M, Lewis, J C M, Morrison, C, Simmonds, P   +4 more
core   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Investigation of depression-like phenotypes and their behavioral correlates in cynomolgus monkeys (Macaca fascicularis)

BMC Zoology
Background The global burden of depression is heavy, with unclear pathogenesis, relying on animal models for researching neural mechanisms and treatments.
Wei Li, Li Huang, Shi-Gang Liu, Jun Tang
doaj   +1 more source

Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV

Advanced Science, EarlyView.
Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes, Gabriela Silva, Mafalda Aleixo, Marta Gomes, Daniel Simão, Stephan J. Holtkamp, Diana D. Lobo, Pradeep Harish, Rosalind Jenkins, Lekh N. Dahal, Rui J. Nobre, Luís de Pereira de Almeida, Mark Trautwein, Paula M. Alves, Catarina Brito   +14 more
wiley   +1 more source

A Tachyplesin Antimicrobial Peptide from Theraphosidae Spiders with Potent Antifungal Activity Against Cryptococcus neoformans

Microorganisms
The venoms of Theraphosidae spiders have evolved into diverse natural pharmacopeias through selective pressures. Cryptococcus neoformans is a global health threat that frequently causes life-threatening meningitis and fungemia, particularly in ...
Brenda B. Michira, Yi Wang, James Mwangi, Kexin Wang, Demeke Asmamaw, Dawit Adisu Tadese, Jinai Gao, Mehwish Khalid, Qiu-Min Lu, Ren Lai, Juan Li   +10 more
doaj   +1 more source

Dilated cardiomyopathy in spider monkey (Ateles chamek, Humboldt, 1812)

Brazilian Journal of Veterinary Medicine, 2019
Non-human primates are routinely studied and managed in zoos, conservation breeding centers, and research centers, but there is currently limited information regarding diseases that can affect these animals.
Mário dos Santos Filho, Heloisa Helena de Campos Coutinho Chaves, Bárbara Souza Neil Magalhães, Andressa Kagohara, Fernando Troccoli, Alessandro Galhões, Daniel de Almeida Balthazar, Jonimar Pereira Paiva   +7 more
doaj   +1 more source

Diversity and development of positional behavior in non-human primates [PDF]

, 2012
In long-term evolution, wildlife in general and primates in particular have formed specific patterns of behavior to adapt to a diverse variety of habitat environments.
GUO, Song-Tao, LI, Bao-Guo, ZHANG, Pei, ZHANG, Jing, QI, Xiao-Guang, WEI, Wei, ZHANG, Kan   +6 more
core   +1 more source

The monkey puzzle: a systematic review of studies of stress, social hierarchies, and heart disease in monkeys. [PDF]

, 2012
BACKGROUND: It is often suggested that psychosocial factors, such as stress, or one's social position, may play an important role in producing social gradients in human disease. Evidence in favour of this model of health inequalities has relied, in part,
Petticrew, Mark, Mark Petticrew (49243), Mark Petticrew, Petticrew Mark, Mark Petticrew, Davey Smith, George, George Davey Smith, Davey Smith George, Smith, George Davey, George Davey Smith (82619)   +9 more
core   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source

Aspects éthiques et cadres juridiques de la recherche en neurosciences comportementales chez les primates non-humains

Revue de Primatologie
Neuroscience research involving animal models is at the heart of major scientific questions. It provides considerable fundamental knowledge about biological mechanisms at the molecular, cellular and integrated levels, and enables the development of ...
Valentine Morel-Latour, Sabrina Ravel, Manon Dirheimer, Jérôme Sallet   +3 more
doaj   +1 more source