Results 81 to 90 of about 317,061 (307)
The psychology of gestures and gesture-like movements in non-human primates [PDF]
, 2014 Research into gestural communication of nonhuman primates is often inspired by an interest in the evolutionary roots of human language. The focus on intentionally used behaviors is central to this approach that aims at investigating the cognitive ...
Liebal, Katja
core +1 more source
Learnable Diffusion Framework for Mouse V1 Neural Decoding
Advanced Science, EarlyView.We introduce Sensorium‐Viz, a diffusion‐based framework for reconstructing high‐fidelity visual stimuli from mouse primary visual cortex activity. By integrating a novel spatial embedding module with a Diffusion Transformer (DiT) and a synthetic‐response augmentation strategy, our model outperforms state‐of‐the‐art fMRI‐based baselines, enabling robust
Kaiwen Deng +2 more
wiley +1 more source
Forelimb movements evoked by optogenetic stimulation of the macaque motor cortex
Nature Communications, 2020 Non-human primates are useful models for understanding the human brain but application of optogenetics to non-human primates is challenging. The authors used optogenetic intracortical microstimulation in the primary motor cortex of macaques to elicit ...
Hidenori Watanabe +7 more
doaj +1 more source
Lymphoid‐Tissue‐on‐Chip Recapitulates Human Antibody Responses In Vitro
Advanced Science, EarlyView.The presented lymphoid‐tissue‐on‐chip system allows culture of primary human tonsil cells at organotypic high density under perfusion for up to 4 weeks, emulates immune response to soluble vaccines and vaccination via peripheral antigen‐presenting cells and represents a useful tool to assess cellular interactions during homeostasis, immune responses ...
Claudia Teufel +15 more
wiley +1 more source
Transferrin Disassociates TCR from CD3 Signaling Apparatus to Promote Metastasis
ResearchImmune recognition and activation by the peptide-laden major histocompatibility complex–T cell receptor (TCR)–CD3 complex is essential for anti-tumor immunity. Tumors may escape immune surveillance by dissembling the complex.
Ruomei Cheng +12 more
doaj +1 more source
Memorias do Instituto Oswaldo Cruz, 2006 A multiplex polymerase chain reaction (PCR) assay was performed on 167 thermophilic campylobacters isolated from non-human primates. Samples were first identified by phenotypic methods resulting in 64 Campylobacter jejuni and 103 C. coli strains.
Mônica de Castro Britto Vilardo +4 more
doaj +1 more source
Neurobiology of Disease, 2020 In order to model various aspects of Huntington's disease (HD) pathology, in particular protein spread, we administered adeno-associated virus (AAV) expressing green fluorescent protein (GFP) or GFP coupled to HTT-Exon1 (19Q or 103Q) to the central ...
Alexander Maxan +14 more
doaj +1 more source
Can the Archaeology of Manual Specialization Tell Us Anything About Language Evolution? A Survey of the State of Play [PDF]
, 2009 In this review and position paper we explore the neural substrates for manual specialization and their possible connection with language and speech. We focus on two contrasting hypotheses of the origins of language and manual specialization: the language-
Steele, J, Uomini, N
core
Advanced Science, EarlyView.The inhibitory immune checkpoints HLA‐G and CD47 are expressed on certain tumor types and inhibit immune cells in the tumor microenvironment. DSP216 binds specifically to cancer cells expressing both HLA‐G and CD47, and blocks their inhibitory signaling.
Lisa J. Jacob +12 more
wiley +1 more source
Animal models of the non-motor features of Parkinson's disease
Neurobiology of Disease, 2012 The non-motor symptoms (NMS) of Parkinson's disease (PD) occur in roughly 90% of patients, have a profound negative impact on their quality of life, and often go undiagnosed.
Kimberly McDowell +1 more
doaj +1 more source