Results 51 to 60 of about 317,061 (307)
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Quality management for the international transportation of non-human primates [PDF]
Veterinaria Italiana, 2008 Safe and humane transportation of live animals requires dedicated, informed personnel who carefully plan and attend to the details of appropriate animal care and handling throughout the shipping process. Specifically, although transportation of non-human
David B. Elmore
doaj
Differentiation of Trichuris species using a morphometric approach [PDF]
, 2019 Trichuris trichiura is a nematode considered as the whipworm present in humans and primates. The systematics of the genus Trichuris is complex. Morphological studies of Trichuris isolated from primates and humans conclude that the species infecting these
Callejón Fernández, Rocío +6 more
core +1 more source
FEBS Open Bio, EarlyView.ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand +2 more
wiley +1 more source
The role of mosquitoes in malaria parasite transmission from non-human primates to humans.
Frontiers in Physiology, 2012 Malaria is caused by Plasmodium parasites which are transmitted by anopheline mosquitoes. Until recently, human malaria was considered to be caused by human-specific Plasmodia spp.
Niels O. Verhulst +3 more
doaj +1 more source
Rapid radiation of treponema pallidum pertenue in wild non-human primates [PDF]
, 2016 Bacteria of the species Treponema pallidum are causative agents of venereal syphilis (Treponema pallidum pallidum), Bejel (T. p. endemicum), and yaws (T. p. pertenue) in humans.
Aki Tanouchi (3461903) +11 more
core +3 more sources
Non-human primates and Leishmania immunity
Cytokine: X, 2020 In the context of infectious diseases, non-human primates (NHP) provide the best animal models of human diseases due to the close phylogenetic relationship and the similar physiology and anatomical systems. Herein, we summarized the contribution of NHP models for understanding the immunity to leishmaniases, which are a group of diseases caused by ...
Sonia André +4 more
openaire +2 more sources
Von Economo Neuron Loss in Frontotemporal Dementia: A Meta‐Analysis of Neuropathological Studies
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Von Economo neurons (VENs) have been reported to be vulnerable to neurodegeneration in frontotemporal dementia (FTD), particularly the behavioral variant (bvFTD), but these findings have not been systematically assessed across independent brain banks.
Daniel Talmasov +2 more
wiley +1 more source
Arthritis Care &Research, EarlyView.Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel +6 more
wiley +1 more source
MicroorganismsThe venoms of Theraphosidae spiders have evolved into diverse natural pharmacopeias through selective pressures. Cryptococcus neoformans is a global health threat that frequently causes life-threatening meningitis and fungemia, particularly in ...
Brenda B. Michira +10 more
doaj +1 more source