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Non-Infectious Uveitis: Optimising the Therapeutic Response
Drugs, 2015Non-infectious uveitis mainly affects the working-age population and can contribute to significant social and economic burden. It comprises a heterogeneous group of conditions with varied aetiology. Precise and early diagnosis, excluding masquerade syndromes, is the key to early therapeutic intervention.
Archana, Airody +3 more
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Optimising drug therapy for non-infectious uveitis
International Ophthalmology, 2018Uveitis encompasses a wide variety of sight-threatening diseases characterized by intraocular inflammation. It is often classified as infectious and non-infectious uveitis. Unlike infectious uveitis, a distinct infectious agent cannot be identified in non-infectious uveitis and disease origin is usually autoimmune, drug related, or idiopathic.Non ...
Mohammad Ali Shahab +2 more
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JAK-STAT signaling pathway in non-infectious uveitis
Biochemical Pharmacology, 2022Non-infectious uveitis (NIU) refers to various intraocular inflammatory disorders responsible for severe visual loss. Cytokines participate in the regulation of ocular homeostasis and NIU pathological processes. Cytokine receptors transmit signals by activating Janus kinase (JAK) and signal transducer and activator of transcription (STAT) proteins ...
Yuhan, Su +3 more
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Intravitreal dexamethasone implants for non‐infectious uveitis
Clinical & Experimental Ophthalmology, 2019AbstractImportanceInflammatory‐mediated cystoid macular oedema (CMO) is the most common inflammatory‐mediated threat to vision in non‐infectious uveitis (NIU). Corticosteroid therapy is the cornerstone to the management of CMO in NIU. Sustained‐release dexamethasone (DEX) implant devices provide localized therapy.BackgroundThe authors present a series ...
Matthew McCartney +2 more
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Therapies in Development for Non-Infectious Uveitis
Current Molecular Medicine, 2015Uveitis represents a spectrum of diseases characterized by ocular inflammation that leads to significant visual loss if left untreated. Adequate, long-term control of inflammation with minimal systemic and local adverse effects is the preferred strategy for treating patients with uveitis.
M A, Sadiq +7 more
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Intravitreal immunotherapy in non-infectious uveitis: an update
Expert Review of Clinical Pharmacology, 2023In the past several years, there have been numerous advances in pharmacotherapeutics for the management of uveitis and other ocular inflammatory diseases, including newer therapeutic agents and ocular drug delivery systems. One of the most attractive modes of drug delivery is the intravitreal route since it has proven to be safe and efficacious and ...
Nitin Kumar, Menia +2 more
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Uveitis in Sarcoidosis – Clinical Features and Comparison with Other Non-infectious Uveitis
Ocular Immunology and Inflammation, 2022Comparison of sarcoid uveitis with other non-infectious uveitis treatment and visual outcomes.Retrospective study of 287 eyes with sarcoid uveitis and 1517 eyes with other non-infectious uveitis (15,029 eye-years follow-up).Sarcoid uveitis patients presented at age 43.1 ± 0.8 years, and 66.2% were female.
Rachael L. Niederer +3 more
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Infectious and non infectious triggers in non‐infectious uveitis
Acta Ophthalmologica, 2010Abstract Purpose The induction of autoimmune uveitis is difficult to explain with respect to the immune privileged status of the eye. The intact BRB can only be passed by already activated leukocytes, which should normally be ignorant to the sequestered intraocular antigens.
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Smoking complicates the course of non-infectious uveitis
Graefe's Archive for Clinical and Experimental Ophthalmology, 2011Data concerning the association of smoking and uveitis are limited. The aim of this study was to evaluate the effect of tobacco smoking on uveitis activity and complications of noninfections uveitis and the need for immunosuppressive therapy.We conducted an observational cross-sectional study in 350 patients with noninfectious uveitis.
Roesel, Martin +4 more
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Intravitreal immunotherapy in non-infectious uveitis
Expert Review of Clinical Pharmacology, 2023Introduction: In the past several years, there have been numerous advances in pharmacotherapeutics for the management of uveitis and other ocular inflammatory diseases, including newer therapeutic agents and ocular drug delivery systems. One of the most attractive modes of drug delivery is the intravitreal route since it has proven to be safe and ...
Menia, Nitin Kumar +2 more
openaire +1 more source