Results 21 to 30 of about 24,187 (251)

A Review of the Various Roles and Participation Levels of B-Cells in Non-Infectious Uveitis

Frontiers in Immunology, 2021
Non-infectious uveitis is an inflammatory disorder of the eye that accounts for severe visual loss without evident infectious agents. While T cells are supposed to dominate the induction of inflammation in non-infectious uveitis, the role of B cells in ...
Lei Zhu, Binyao Chen, Wenru Su
doaj   +1 more source

Non-infectious pediatric uveitis

Bulgarian Review of Ophthalmology, 2020
Because of the varied spectrum of clinical presentation and difficulty in management, pediatric uveitis remains a challenge to the ophthalmologist. Variations in clinical presentation, difficulties in the eye examination, extended burden of the inflammation over quality of life, limited treatment modalities, risk of amblyopia are among the main ...
M. Markova, Al. Oscar
openaire   +2 more sources

Guidance on Noncorticosteroid Systemic Immunomodulatory Therapy in Noninfectious Uveitis : Fundamentals Of Care for UveitiS (FOCUS) Initiative [PDF]

, 2018
Supplemental material available at www.aaojournal.org. Supported by AbbVie, Inc., and the Fundamentals of Care for Uveitis Initiative National Faculty.
Accorinti, Massimo, Acharya, Nisha, Adan, Alfredo, Agrawal, Rupesh, Akkoc, Nurullah, Al Ghamdi, Saed, Al Ghamdi, Turki, Al Saati, Anood, Al-Dhibi, Hassan A., Al-Shamarani, Mohamed, Alsabaani, Nasser, Bachta, Artur, Barisani-Asenbauer, Talin, Beare, Nicholas, Belfort, Rubens, Blanco, Ricardo, Brézin, Antoine P., Carreño, Ester, Chandran, Vinod, Chee, Soon Phaik, Chiquet, Christophe, Chng, Hiok Hee, Cimbalas, Andrius, Cimino, Luca, Cordero-Coma, Miguel, Cristobal, Couto, Cuevas, Miguel, Davis, Janet L., de Boer, Joke, de la Torre, Alejandra, De Schryver, Ilse, Derzko-Dzulynsky, Larissa, Diaz-Valle, David, Dick, Andrew D., Eurico da Fonseca, João, Facsko, Andrea, Figueira, Luis, Fundamentals of Care for Uveitis International Consensus Group, Kuffova, Lucia, Merino, Claudia Eugenia Duran, Murphy, Conor, Nascimento, Heloisa, Porto, Fernanda Belga Ottoni, Ramanan, Athimalaipet V., Rosenbaum, James T., Salah, Sawsen, Salek, Sherveen, Siak, Jay, Sonoda, Koh Hei, Steeples, Laura, Yee, Anita Chan Sook   +50 more
core   +4 more sources

Electroretinogram abnormalities in non‐infectious uveitis often persist [PDF]

Acta Ophthalmologica, 2020
AbstractPurposeIn uveitis, a prolonged implicit time of the cone b‐wave is a characteristic electroretinogram (ERG) abnormality. We investigated whether this can improve or deteriorate over time and which clinical factors are associated with change.MethodsProspective cohort study. Patients with a non‐infectious uveitis were included.
Anna H. Brouwer, Gerard C. de Wit, Ninette H. ten Dam, Ralph Wijnhoven, Maria M. van Genderen, Joke H. de Boer   +5 more
openaire   +3 more sources

Adhesion Molecule Targeted Therapy for Non-Infectious Uveitis [PDF]

International Journal of Molecular Sciences, 2022
Non-infectious uveitis (NIU) is an inflammatory eye disease initiated via CD4+ T-cell activation and transmigration, resulting in focal retinal tissue damage and visual acuity disturbance. Cell adhesion molecules (CAMs) are activated during the inflammatory process to facilitate the leukocyte recruitment cascade.
Chen, YH, Lightman, S, Eskandarpour, M, Calder, VL   +3 more
openaire   +3 more sources

Uveitis and nail psoriasis in a patient without articular involvement: a case report

BMC Ophthalmology, 2022
Background This study aimed to report a case of bilateral anterior non-granulomatous chronic non-infectious uveitis associated with isolated nail psoriasis without articular involvement.
Juan Sebastián Pineda-Sierra, Luisa Fernanda Peña-Pulgar, Carlos Cifuentes-González, William Rojas-Carabali, Alejandra de-la-Torre   +4 more
doaj   +1 more source

Clinical patterns and characteristics of uveitis in a secondary hospital in southern China [PDF]

International Journal of Ophthalmology, 2015
AIM: To investigate the characteristics of uveitis in a secondary hospital in southern China. METHODS: We reviewed all records of patients with uveitis at Hengli Hospital from January 2008 to December 2011.
Yang Zheng, Li-Xin Zhang, Qian-Li Meng, Min Zhang, Ying Cui, Qing-Yang Liu, Zhong-Ling Luo, Li-Ping Du   +7 more
doaj   +1 more source

Metagenomic deep sequencing of aqueous fluid detects intraocular lymphomas. [PDF]

, 2017
IntroductionCurrently, the detection of pathogens or mutations associated with intraocular lymphomas heavily relies on prespecified, directed PCRs. With metagenomic deep sequencing (MDS), an unbiased high-throughput sequencing approach, all pathogens as ...
Acharya, Nisha, Bloomer, Michele, DeRisi, Joseph L, Doan, Thuy, Gonzales, John, Shantha, Jessica G, Wilson, Michael R   +6 more
core   +1 more source

Emerging Treatments for Non-infectious Uveitis [PDF]

US Ophthalmic Review, 2018
The primary goals of treatment in patients with non-infectious uveitis (NIU) are to control ocular inflammation and prevent sight-threatening complications such as macular edema and glaucoma. Systemic corticosteroids are the mainstay of treatment in NIU of the posterior segment (NIU-PS); however, long-term use is associated with treatment-limiting ...
Pauline Merrill, Carlos Pavesio, Alay S Banker   +2 more
openaire   +1 more source

No association of CTLA-4 polymorphisms with susceptibility to Behcet disease [PDF]

, 2009
Background: Cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) is a key negative regulator of T lymphocytes and has been shown to be associated with a number of autoimmune diseases. The present study was performed to assess the association between CTLA-
Du, L., Hou, S., Kijlstra, A., Yang, P., Zhou, H.   +4 more
core   +5 more sources