Results 91 to 100 of about 6,758 (218)

Cationic‐Hydrophilic Di‐Block Copolymers: Surface‐Shielded Vectors for Gene Delivery

Journal of Polymer Science, Volume 63, Issue 6, Page 1419-1432, 15 March 2025.
This study develops synthetic polycationic di‐block carriers for nucleic acid (NA) delivery in gene therapy. Consisting of a cationic block and a hydrophilic block, these carriers efficiently form complexes with NAs and shield them with a protective bioinert layer, enhancing stability during circulation in the bloodstream while reducing undesirable ...
Eliška Hrdá, Ladislav Androvič, Marcela Filipová, Michal Pechar, Richard Laga   +4 more
wiley   +1 more source

A Multiple‐Model‐Informed Drug‐Development Approach for Optimal Regimen Selection of an Oncolytic Virus in Combination With Pembrolizumab

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 572-582, March 2025.
ABSTRACT The antitumor efficacy of an intratumoral injection of a genetically engineered oncolytic vaccinia virus carrying human IL‐7 and murine IL‐12 genes (hIL‐7/mIL‐12‐VV) was demonstrated in CT26.WT‐bearing mice. In the CT26.WT‐bearing mouse model, the efficacy of the combination of hIL‐7/mIL‐12‐VV plus the anti‐programmed cell death protein (PD)‐1
Akihiro Yamada, Mary P. Choules, Frances A. Brightman, Shigeru Takeshita, Shinsuke Nakao, Nobuaki Amino, Takeshi Nakayama, Masato Takeuchi, Kanji Komatsu, Fernando Ortega, Hitesh Mistry, David Orrell, Christophe Chassagnole, Peter L. Bonate   +13 more
wiley   +1 more source

Physics‐Informed Neural Networks for Battery Degradation Prediction Under Random Walk Operations

Quality and Reliability Engineering International, EarlyView.
ABSTRACT This study addresses the challenge of predicting the state of health (SoH) and capacity degradation in Battery Energy Storage Systems (BESS) under highly variable conditions induced by frequent control adjustments. In environments where random walk behavior prevails due to stochastic control commands, conventional estimation methods often ...
Alaa Selim, Huadong Mo, Hemanshu Pota, Daoyi Dong   +3 more
wiley   +1 more source

Design of non-linear MPC for energy-efficient train operations

, 2020
LAUREA MAGISTRALELa strategia dell’eco-drive è una tecnica diffusa nei sistemi di trasporto per diminuire il consumo di energia. Tecniche di eco-drive sono applicate anche in sistemi ferroviari per migliorare l'efficienza energetica.
Cinelli, Matteo
core  

Enhancing Reference Tracking in Induction Motor Drives: A Hybrid Model Predictive Control and Artificial Neural Network Approach

International Journal of Robust and Nonlinear Control, EarlyView.
ABSTRACT Induction motors (IMs) are widely used in industry for their robustness and cost‐effectiveness, yet their nonlinear and multivariable dynamics pose significant challenges for high‐performance speed control. Model Predictive Control (MPC) is a well‐established solution but suffers from limitations related to model accuracy and parameter ...
Asier del Rio, Oscar Barambones, Eneko Artetxe, Jokin Uralde, Isidro Calvo   +4 more
wiley   +1 more source

Control System for the Navigation of the Agricultural Robots: A Review

Journal of Field Robotics, EarlyView.
ABSTRACT Control systems for the navigation of autonomous agricultural robots—particularly those operating in uneven terrain and in the presence of static or dynamic obstacles—have advanced considerably in recent years. As conventional machinery evolves toward increasingly automated systems, the design of reliable navigation controllers has become ...
Edna Carolina Moriones Polanía, Hugo Rafacho Fernandes, Daniel Albiero, Angel Pontin Garcia   +3 more
wiley   +1 more source

From Waste to Value: A Data‐Driven Framework for Sustainable Raw Materials Substitution in the Ceramic Industry

Sustainable Development, EarlyView.
ABSTRACT With increasing geopolitical risks, environmental pressures, and regulatory demands, the sustainable sourcing of raw materials has become a global priority for achieving the United Nations Sustainable Development Goals (SDGs), particularly SDG 9 (Industry, Innovation and Infrastructure), SDG 12 (Responsible Consumption and Production), and SDG
Francesco Parisi, Luciana Randazzo, Davide Settembre Blundo, Isabella Ganci, Silvestro Antonio Ruffolo, Mauro Francesco La Russa   +5 more
wiley   +1 more source

MPC for Transportation and Injection of CO2 [PDF]

Denne masteroppgaven implementerer en industriell MPC og en dynamisk sanntidsmodell for transport og injeksjon av flytende CO2 for karbonlagrings-formål.
Ruud, Trygve
core  

Biomaterial‐Integrated Electroporation for Therapeutic Delivery: From Gene Editing to Tumor Ablation and Immune Modulation

Small, EarlyView.
Biomaterial‐integrated electroporation establishes a programmable therapeutic interface that coordinates electric‐field modulation, transient or irreversible membrane permeabilization, cargo stabilization, and immune remodeling. This Review highlights how nanocarriers, hydrogels, and bioelectronic interfaces expand electroporation from conventional ...
Binbin Ji, Zhuozhuo Wu, Yuyue Jiang, Xiaoyu Liu, Jingfeng Li, Fengkuo Xu, Chaojie Li, Qungang Shan, Ziyin Wang, Junhao Wang, Wei Huang, Yaping Zhuang, Wenguo Cui, Zhongmin Wang   +13 more
wiley   +1 more source

Creep Performance of Stainless Steel 316 Brackets: Insights From Conventional and Advanced Modeling Approaches

steel research international, EarlyView.
Creep behavior of SS 316 brackets is examined through experiments, conventional creep laws, and advanced constitutive modeling. Long‐term deformation, stress redistribution, and life prediction are compared under service‐relevant loads. The study highlights the limits of classical models and demonstrates improved accuracy using advanced approaches for ...
Mohsin Sattar, Jan Hosek, Maaz Akhtar, Uliana Finaeva, Muhammad Muzamil, Naser A. Alsaleh, Asad A. Zaidi, Barun Haldar   +7 more
wiley   +1 more source