Results 121 to 130 of about 14,021,594 (346)

A blood-based biomarker panel (NIS4) for non-invasive diagnosis of non-alcoholic steatohepatitis and liver fibrosis: a prospective derivation and global validation study.

The Lancet Gastroenterology and Hepatology, 2020
BACKGROUND Non-invasive tests that can identify patients with non-alcoholic steatohepatitis (NASH) at higher risk of disease progression are lacking. We report the development and validation of a blood-based diagnostic test to non-invasively rule in and ...
S. Harrison, V. Ratziu, J. Boursier, S. Francque, P. Bedossa, Z. Majd, G. Cordonnier, F. B. Sudrik, R. Darteil, R. Liebe, Jérémy Magnanensi, Yacine Hajji, J. Brozek, A. Roudot, B. Staels, D. Hum, S. Megnien, S. Hosmane, Noémie Dam, P. Chaumat, Rémy Hanf, Q. Anstee, A. Sanyal   +22 more
semanticscholar   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Long-term effects on cardiac function and symptoms in patients with myocarditis following COVID-19 vaccination: the ECHOVID-19 Long-term Study

Open Heart
Background The long-term effects of myocarditis following COVID-19 vaccination on cardiac function and symptoms remain unclear.Purpose To assess the long-term effects of myocarditis following COVID-19 vaccination on cardiac function, inflammatory ...
Manan Pareek, Tor Biering-Sørensen, Anders Hviid, Filip Soeskov Davidovski, Kristoffer Grundtvig Skaarup, Mohammad Nizar Ramadan, Caroline Espersen, Ali Hikmat Al-Rubai, Ayat Khoraizat, Niklas Dyrby Johansen, Mats Christian Højbjerg Lassen, Tyra Grove   +11 more
doaj   +1 more source

Easl Clinical Practice Guidelines (Cpgs) On Non-Invasive Tests For Evaluation Of Liver Disease Severity And Prognosis- 2020 Update.

Journal of Hepatology, 2021
A. Berzigotti, J. Boursier, L. Castéra, N. Cazzagon, M. Friedrich-Rust, S. Petta, M. Thiele, E. Tsochatzis   +7 more
semanticscholar   +1 more source

Human Saliva: Non-Invasive Fluid for Detecting Novel Coronavirus (2019-nCoV)

International Journal of Environmental Research and Public Health, 2020
The breakthrough of novel coronavirus (2019-nCoV) in Wuhan, a city of China, has damaged the status of health and quality of life. In the sequel of this epidemic or contagious disease, the patient experiences fever, chest paint, chills, a rapid heartbeat,
Z. Khurshid, Faris Yahya I Asiri, H. Al Wadaani   +2 more
semanticscholar   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Non-invasive thermometer based on proximity superconductor for ultra-sensitive calorimetry

, 2018
We present radio-frequency thermometry based on a tunnel junction between a superconductor and proximitized normal metal. It allows operation in a wide range of biasing conditions.
Karimi, Bayan, Pekola, Jukka P.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Semantic reconstruction of continuous language from non-invasive brain recordings

bioRxiv, 2022
Jerry Tang, Amanda LeBel, Shailee Jain, Alexander G. Huth   +3 more
semanticscholar   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source