Results 91 to 100 of about 4,445,152 (279)

An African Art Re-Discovered: New Revelations on Sword Manufacture in Dahomey

Heritage
Antique swords from the pre-colonial West African kingdom of Dahomey are aesthetically unique, but they also have many design features inspired by swords from Europe, the Islamic world and elsewhere.
Ron Lawrence Anderson, Filomena Salvemini, Maxim Avdeev, Vladimir Luzin   +3 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Transcriptome Analysis Showed a Differential Signature between Invasive and Non-invasive Corticotrophinomas

Frontiers in Endocrinology, 2017
ACTH-dependent hypercortisolism caused by a pituitary adenoma [Cushing’s disease (CD)] is the most common cause of endogenous Cushing’s syndrome. CD is often associated with several morbidities, including hypertension, diabetes, osteoporosis/bone ...
Leonardo Jose Tadeu de Araújo, Leonardo Jose Tadeu de Araújo, Antonio Marcondes Lerario, Antonio Marcondes Lerario, Margaret de Castro, Clarissa Silva Martins, Marcello Delano Bronstein, Marcello Delano Bronstein, Marcio Carlos Machado, Marcio Carlos Machado, Marcio Carlos Machado, Ericka Barbosa Trarbach, Maria Candida Barisson Villares Fragoso, Maria Candida Barisson Villares Fragoso   +13 more
doaj   +1 more source

Comparator choice in cariology trials limits conclusions on the comparative effectiveness of caries interventions [PDF]

, 2017
Comparator choice has been found one major factor impacting on the overall evidence supporting clinical interventions. We performed social network analysis on trials on the prevention/management of caries/carious lesions, hypothesizing that certain ...
Göstemeyer, Gerd, Innes, Nicola, Lamont, Thomas, Levey, Colin, Schwendicke, Falk   +4 more
core   +3 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Gene expression profiling in bladder cancer identifies potential therapeutic targets [PDF]

, 2017
Despite advances in management, bladder cancer remains a major cause of cancer related complications. Characterisation of gene expression patterns in bladder cancer allows the identification of pathways involved in its pathogenesis, and may stimulate the
Aachi, Vijay, Ansari, Jawaher, Arrand, J, Barton, D, Collins, S, Elmetwali, Taha, Greensmith, Richard MD, Hussain, S, James, ND, Jithesh, Puthen V, Lloyd, B, Palmer, D, Sacco, J, Sibson, R, Syn, WK   +14 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Trends in Vibrational Spectroscopy: NIRS and Raman Techniques for Health and Food Safety Control

Sensors
There is an increasing need to establish reliable safety controls in the food industry and to protect public health. Consequently, there are numerous efforts to develop sensitive, robust, and selective analytical strategies.
Candela Melendreras, Jesús Montero, José M. Costa-Fernández, Ana Soldado, Francisco Ferrero, Francisco Fernández Linera, Marta Valledor, Juan Carlos Campo   +7 more
doaj   +1 more source

Non invasive methods for genetic analysis applied to ecological and behavioral studies in Latino-America

Revista Brasileira de Zootecnia, 2007
Documenting the presence and abundance of the neotropical mammals is the first step for understanding their population ecology, behavior and genetic dynamics in designing conservation plans.
Susana González, José Mauricio Barbanti Duarte   +1 more
doaj   +1 more source

Breath Tests for the Non-invasive Diagnosis of Small Intestinal Bacterial Overgrowth: A Systematic Review With Meta-analysis

Journal of Neurogastroenterology and Motility, 2019
Background/Aims Small intestinal bacterial overgrowth (SIBO) diagnosis is usually based on non-invasive breath tests (BTs), namely lactulose BT (LBT) and glucose BT (GBT).
G. Losurdo, G. Leandro, E. Ierardi, F. Perri, M. Barone, M. Principi, A. Leo   +6 more
semanticscholar   +1 more source