Results 81 to 90 of about 2,756,582 (315)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Ancestral origins and invasion pathways in a globally invasive bird correlate with climate and influences from bird trade [PDF]

open access: yes, 2015
Invasive species present a major threat to global biodiversity. Understanding genetic patterns and evolutionary processes that reinforce successful establishment is para- mount for elucidating mechanisms underlying biological invasions.
Tollington, S   +15 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Trends in Vibrational Spectroscopy: NIRS and Raman Techniques for Health and Food Safety Control

open access: yesSensors
There is an increasing need to establish reliable safety controls in the food industry and to protect public health. Consequently, there are numerous efforts to develop sensitive, robust, and selective analytical strategies.
Candela Melendreras   +7 more
doaj   +1 more source

Transcriptome Analysis Showed a Differential Signature between Invasive and Non-invasive Corticotrophinomas

open access: yesFrontiers in Endocrinology, 2017
ACTH-dependent hypercortisolism caused by a pituitary adenoma [Cushing’s disease (CD)] is the most common cause of endogenous Cushing’s syndrome. CD is often associated with several morbidities, including hypertension, diabetes, osteoporosis/bone ...
Leonardo Jose Tadeu de Araújo   +13 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Non-invasive imaging of subsurface paint layers with optical coherence tomography

open access: yes, 2007
Optical coherence tomography (OCT) systems are fast scanning infrared Michelson interferometers designed for the non-invasive examination of the interiors of the eye and subsurface structures of biological tissues.
Saunders, D   +5 more
core  

Conservation, Society and Invasive Species [PDF]

open access: yes, 2011
Invasive species pose a major environmental threat, and are frequently the subject of biodiversity conservation programmes. As stakeholder and public concerns surrounding invasive species have become increasingly recognised and better articulated ...
Ford-Thompson, Adriana E S   +1 more
core  

Development of a non-invasive CO2 breath sensor with IoT integration [PDF]

open access: yes
Breath analysis offers a non-invasive, rapid, and cost effective method for diagnosing respiratory diseases and monitoring various health conditions. However, non-invasive breath analysis techniques often suffer from lower sensitivity and specificity ...
Shamsudin, Nur Hazahsha   +5 more
core   +1 more source

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